Murcko scaffold

Ring system with 4 rings and 23 atoms

38 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 23
Chemicals: 38
With full pages: 5

Scaffold SMILES

O=C1Cc2cc(S(=O)(=O)Nc3ccccc3)cc3c2N1CCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C1Cc2cc(S(=O)(=O)Nc3ccccc3)cc3c2N1CCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 38 of 38 chemicals

N-(3-Methoxyphenyl)-2-oxo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 896375-27-2C₁₈H₁₈N₂O₄S

N-(2-Ethylphenyl)-2-oxo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 896375-41-0C₁₉H₂₀N₂O₃S

N-(2-Methoxyphenyl)-2-oxo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 887880-20-8C₁₈H₁₈N₂O₄S

$N-(4-Methoxy-2-nitrophenyl)-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-triene-6-sulfonamide chemical structure, C18H17N3O6S, CAS 886893-24-9$

N-(4-Methoxy-2-nitrophenyl)-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-triene-6-sulfonamide

CAS 886893-24-9C₁₈H₁₇N₃O₆S

$N-[4-(Dimethylamino)phenyl]-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-triene-6-sulfonamide chemical structure, C19H21N3O3S, CAS 896376-43-5$

N-[4-(Dimethylamino)phenyl]-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-triene-6-sulfonamide

CAS 896376-43-5C₁₉H₂₁N₃O₃S

$N-(5-Chloro-2-methoxyphenyl)-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-triene-6-sulfonamide chemical structure, C18H17ClN2O4S, CAS 896376-01-5$

N-(5-Chloro-2-methoxyphenyl)-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-triene-6-sulfonamide

CAS 896376-01-5C₁₈H₁₇ClN₂O₄S

N-(5-Chloro-2-methylphenyl)-2-oxo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 896376-21-9C₁₈H₁₇ClN₂O₃S

N-(5-Chloro-2-methoxyphenyl)-1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898455-17-9C₁₉H₁₉ClN₂O₄S

N-(4-Bromophenyl)-1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898427-20-8C₁₈H₁₇BrN₂O₃S

$Methyl 2-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-triene-6-sulfonamido}benzoate chemical structure, C20H20N2O5S, CAS 898455-01-1$

Methyl 2-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-triene-6-sulfonamido}benzoate

CAS 898455-01-1C₂₀H₂₀N₂O₅S

$N-[4-Fluoro-3-(trifluoromethyl)phenyl]-3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-triene-6-sulfonamide chemical structure, C19H16F4N2O3S, CAS 903361-97-7$

N-[4-Fluoro-3-(trifluoromethyl)phenyl]-3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-triene-6-sulfonamide

CAS 903361-97-7C₁₉H₁₆F₄N₂O₃S

N-(2-Fluorophenyl)-1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898427-23-1C₁₈H₁₇FN₂O₃S

N-(2,4-Difluorophenyl)-1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898455-05-5C₁₈H₁₆F₂N₂O₃S

$N-(2,5-Difluorophenyl)-3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-triene-6-sulfonamide chemical structure, C18H16F2N2O3S, CAS 898427-24-2$

N-(2,5-Difluorophenyl)-3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-triene-6-sulfonamide

CAS 898427-24-2C₁₈H₁₆F₂N₂O₃S

N-(4-Fluorophenyl)-1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898411-58-0C₁₈H₁₇FN₂O₃S

N-(3-Fluorophenyl)-1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898455-07-7C₁₈H₁₇FN₂O₃S

N-(3-Fluoro-4-methylphenyl)-1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898427-25-3C₁₉H₁₉FN₂O₃S

N-(3-Chloro-4-methoxyphenyl)-1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898427-26-4C₁₉H₁₉ClN₂O₄S

N-(2,4-Dichlorophenyl)-1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898411-62-6C₁₈H₁₆Cl₂N₂O₃S

N-(2,3-Dichlorophenyl)-1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898455-11-3C₁₈H₁₆Cl₂N₂O₃S

$Methyl 4-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-triene-6-sulfonamido}benzoate chemical structure, C20H20N2O5S, CAS 898427-28-6$

Methyl 4-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-triene-6-sulfonamido}benzoate

CAS 898427-28-6C₂₀H₂₀N₂O₅S

N-(4-Bromo-3-methylphenyl)-1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898427-30-0C₁₉H₁₉BrN₂O₃S

N-(3-Chloro-2-methylphenyl)-1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898455-15-7C₁₉H₁₉ClN₂O₃S

$N-(2-Chlorophenyl)-3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-triene-6-sulfonamide chemical structure, C18H17ClN2O3S, CAS 898427-32-2$

N-(2-Chlorophenyl)-3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-triene-6-sulfonamide

CAS 898427-32-2C₁₈H₁₇ClN₂O₃S

Ring system with 4 rings and 23 atoms

Chemicals with this scaffold

Related scaffolds