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Murcko scaffold

N-(1,3-Thiazol-2-yl)naphthalene-2-carboxamide scaffold

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
10
With full pages
3
Scaffold SMILES

O=C(Nc1nccs1)c1ccc2ccccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(1,3-Thiazol-2-yl)naphthalene-2-carboxamide page
Murcko scaffold O=C(Nc1nccs1)c1ccc2ccccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

3-Hydroxy-N-(1,3-thiazol-2-yl)naphthalene-2-carboxamide chemical structure, C14H10N2O2S, CAS 24445-28-1
3-Hydroxy-N-(1,3-thiazol-2-yl)naphthalene-2-carboxamide
CAS 24445-28-1C14H10N2O2S
3-Methoxy-N-(1,3-thiazol-2-yl)naphthalene-2-carboxamide chemical structure, C15H12N2O2S, CAS 313226-58-3
3-Methoxy-N-(1,3-thiazol-2-yl)naphthalene-2-carboxamide
CAS 313226-58-3C15H12N2O2S
N-(1,3-Thiazol-2-yl)naphthalene-2-carboxamide chemical structure, C14H10N2OS, CAS 332886-54-1
N-(1,3-Thiazol-2-yl)naphthalene-2-carboxamide
CAS 332886-54-1C14H10N2OS
N-(4-tert-Butyl-1,3-thiazol-2-yl)naphthalene-2-carboxamide chemical structure, C18H18N2OS, CAS 325988-16-7
N-(4-tert-Butyl-1,3-thiazol-2-yl)naphthalene-2-carboxamide
CAS 325988-16-7C18H18N2OS
N-(5-Acetyl-4-methylthiazol-2-yl)-3-methoxy-2-naphthamide chemical structure, C18H16N2O3S, CAS 324538-58-1
N-(5-Acetyl-4-methylthiazol-2-yl)-3-methoxy-2-naphthamide
CAS 324538-58-1C18H16N2O3S
Ethyl 2-(3-methoxy-2-naphthamido)-4-methylthiazole-5-carboxylate chemical structure, C19H18N2O4S, CAS 312914-27-5
Ethyl 2-(3-methoxy-2-naphthamido)-4-methylthiazole-5-carboxylate
CAS 312914-27-5C19H18N2O4S
N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)naphthalene-2-carboxamide chemical structure, C17H14N2O2S, CAS 391222-34-7
N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)naphthalene-2-carboxamide
CAS 391222-34-7C17H14N2O2S
Ethyl 3,4-dimethyl-2-(naphthalene-2-carbonylimino)-1,3-thiazole-5-carboxylate chemical structure, C19H18N2O3S, CAS 476628-23-6
Ethyl 3,4-dimethyl-2-(naphthalene-2-carbonylimino)-1,3-thiazole-5-carboxylate
CAS 476628-23-6C19H18N2O3S
Ethyl 2-(naphthalene-2-carbonylamino)-1,3-thiazole-4-carboxylate chemical structure, C17H14N2O3S, CAS 247056-86-6
Ethyl 2-(naphthalene-2-carbonylamino)-1,3-thiazole-4-carboxylate
CAS 247056-86-6C17H14N2O3S
Ethyl 2-(3-methoxynaphthalene-2-carbonyl)imino-3,4-dimethyl-1,3-thiazole-5-carboxylate chemical structure, C20H20N2O4S, CAS 476643-60-4
Ethyl 2-(3-methoxynaphthalene-2-carbonyl)imino-3,4-dimethyl-1,3-thiazole-5-carboxylate
CAS 476643-60-4C20H20N2O4S