Murcko scaffold
1H-Pyrazolo[3,4-c]pyridine scaffold
391 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 391
- With full pages
- 35
Scaffold SMILES
c1cc2c[nH]nc2cn1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold c1cc2c[nH]nc2cn1](/scaffold/KNYHISBJRQVMAZ-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 391 chemicals
5-Chloro-1H-pyrazolo(3,4-c)pyridine
CAS 76006-08-1C6H4ClN3
![3,5-Dichloro-1H-pyrazolo[3,4-c]pyridine chemical structure, C6H3Cl2N3, CAS 245325-29-5](/s/OSKGXLAQVINJHQ-UHFFFAOYSA-N.svg)
3,5-Dichloro-1H-pyrazolo[3,4-c]pyridine
CAS 245325-29-5C6H3Cl2N3
3-Chloro-1H-pyrazolo(3,4-c)pyridine
CAS 76006-14-9C6H4ClN3
![1H-Pyrazolo[3,4-c]pyridine chemical structure, C6H5N3, CAS 271-47-6](/s/KNYHISBJRQVMAZ-UHFFFAOYSA-N.svg)
1H-Pyrazolo[3,4-c]pyridine
CAS 271-47-6C6H5N3
![1H-Pyrazolo[3,4-c]pyridin-3-amine chemical structure, C6H6N4, CAS 76006-17-2](/s/LGZRIKTZAOPKET-UHFFFAOYSA-N.svg)
1H-Pyrazolo[3,4-c]pyridin-3-amine
CAS 76006-17-2C6H6N4
![1H-Pyrazolo[3,4-C]pyridin-7-amine chemical structure, C6H6N4, CAS 518038-78-3](/s/SGFRUQZYZBPQCJ-UHFFFAOYSA-N.svg)
1H-Pyrazolo[3,4-C]pyridin-7-amine
CAS 518038-78-3C6H6N4
![1H-Pyrazolo[3,4-C]pyridin-1-amine chemical structure, C6H6N4, CAS 55271-15-3](/s/AEJBZZALMHIMSW-UHFFFAOYSA-N.svg)
1H-Pyrazolo[3,4-C]pyridin-1-amine
CAS 55271-15-3C6H6N4
![Ethyl 1,3-dimethyl-1H-pyrazolo[3,4-c]pyridine-5-carboxylate chemical structure, C11H13N3O2, CAS 72374-19-7](/s/KDWAORPTPXMZNQ-UHFFFAOYSA-N.svg)
Ethyl 1,3-dimethyl-1H-pyrazolo[3,4-c]pyridine-5-carboxylate
CAS 72374-19-7C11H13N3O2
![Ethanone, 1-(5-methyl-1H-pyrazolo[3,4-c]pyridin-1-yl)- chemical structure, C9H9N3O, CAS 76006-01-4](/s/BLJPFSGJXUXHEY-UHFFFAOYSA-N.svg)
Ethanone, 1-(5-methyl-1H-pyrazolo[3,4-c]pyridin-1-yl)-
CAS 76006-01-4C9H9N3O
![1-(5-Methoxy-1H-pyrazolo[3,4-c]pyridin-1-yl)ethanone chemical structure, C9H9N3O2, CAS 76006-02-5](/s/PAMSYYQRIZGVRS-UHFFFAOYSA-N.svg)
1-(5-Methoxy-1H-pyrazolo[3,4-c]pyridin-1-yl)ethanone
CAS 76006-02-5C9H9N3O2
1-(5-Chloro-pyrazolo(3,4-c)pyridin-1-yl)-ethanone
CAS 76006-04-7C8H6ClN3O
![1-(7-Methoxy-1H-pyrazolo[3,4-c]pyridin-1-yl)ethan-1-one chemical structure, C9H9N3O2, CAS 76006-19-4](/s/JRIVZMPHOYYQPF-UHFFFAOYSA-N.svg)
1-(7-Methoxy-1H-pyrazolo[3,4-c]pyridin-1-yl)ethan-1-one
CAS 76006-19-4C9H9N3O2
![1-{7-Methoxy-2H-pyrazolo[3,4-c]pyridin-2-yl}ethan-1-one chemical structure, C9H9N3O2, CAS 76006-05-8](/s/DHAOZAOSPZQQEE-UHFFFAOYSA-N.svg)
1-{7-Methoxy-2H-pyrazolo[3,4-c]pyridin-2-yl}ethan-1-one
CAS 76006-05-8C9H9N3O2
![5-Methyl-1H-pyrazolo[3,4-c]pyridine chemical structure, C7H7N3, CAS 76006-06-9](/s/NGMNOLUZNGMBAI-UHFFFAOYSA-N.svg)
5-Methyl-1H-pyrazolo[3,4-c]pyridine
CAS 76006-06-9C7H7N3
![5-Methoxy-1H-pyrazolo[3,4-c]pyridine chemical structure, C7H7N3O, CAS 76006-07-0](/s/YLHHBXAFEMTGOY-UHFFFAOYSA-N.svg)
5-Methoxy-1H-pyrazolo[3,4-c]pyridine
CAS 76006-07-0C7H7N3O
7-Methoxy-1H-pyrazolo(3,4-c)pyridine
CAS 76006-10-5C7H7N3O
![7-Chloro-1H-pyrazolo[3,4-c]pyridine chemical structure, C6H4ClN3, CAS 76006-11-6](/s/LGYXPMDWRGMZCV-UHFFFAOYSA-N.svg)
7-Chloro-1H-pyrazolo[3,4-c]pyridine
CAS 76006-11-6C6H4ClN3
3-Bromo-1H-pyrazolo(3,4-c)pyridine
CAS 76006-13-8C6H4BrN3
![3-Bromo-5-chloro-1H-pyrazolo[3,4-C]pyridine chemical structure, C6H3BrClN3, CAS 245325-30-8](/s/OIWHFIVQONMGEC-UHFFFAOYSA-N.svg)
3-Bromo-5-chloro-1H-pyrazolo[3,4-C]pyridine
CAS 245325-30-8C6H3BrClN3
![5-Chloro-1H-pyrazolo[3,4-c]pyridin-3-amine chemical structure, C6H5ClN4, CAS 245325-32-0](/s/YTVCEQKHPBTCQI-UHFFFAOYSA-N.svg)
5-Chloro-1H-pyrazolo[3,4-c]pyridin-3-amine
CAS 245325-32-0C6H5ClN4
![1H-Pyrazolo[3,4-c]pyridine-3-carbonitrile chemical structure, C7H4N4, CAS 245325-34-2](/s/VEZNENZOHDDKQD-UHFFFAOYSA-N.svg)
1H-Pyrazolo[3,4-c]pyridine-3-carbonitrile
CAS 245325-34-2C7H4N4
![5-Chloro-1H-pyrazolo[3,4-c]pyridine-3-carbonitrile chemical structure, C7H3ClN4, CAS 245325-35-3](/s/RCSOKOQHMUZLTN-UHFFFAOYSA-N.svg)
5-Chloro-1H-pyrazolo[3,4-c]pyridine-3-carbonitrile
CAS 245325-35-3C7H3ClN4
![1H-Pyrazolo[3,4-c]pyridine-5-methanamine dihydrochloride chemical structure, C7H10Cl2N4, CAS 267875-15-0](/s/IXGAFVVVJDNZHC-UHFFFAOYSA-N.svg)
1H-Pyrazolo[3,4-c]pyridine-5-methanamine dihydrochloride
CAS 267875-15-0C7H10Cl2N4
![(1H-Pyrazolo[3,4-c]pyridin-5-yl)methanamine chemical structure, C7H8N4, CAS 744187-03-9](/s/PEGHUXZJXXDYAX-UHFFFAOYSA-N.svg)
(1H-Pyrazolo[3,4-c]pyridin-5-yl)methanamine
CAS 744187-03-9C7H8N4
- 1-[5-(Bromomethyl)pyrazolo[3,4-c]pyridin-1-yl]ethanone1434283-63-2C9H8BrN3O
- 3-Methyl-1H-pyrazolo[3,4-c]pyridine1072249-89-8C7H7N3
- tert-Butyl 3-methyl-1H-pyrazolo[3,4-c]pyridine-1-carboxylate1072249-90-1C12H15N3O2
- tert-Butyl 3-(bromomethyl)-1H-pyrazolo[3,4-C]pyridine-1-carboxylate1072249-79-6C12H14BrN3O2
- 5-Bromo-3-methyl-1H-pyrazolo[3,4-c]pyridine929617-30-1C7H6BrN3
- 1H-Pyrazolo[3,4-C]pyridine-5-carbonitrile633328-50-4C7H4N4
- 1-Acetylpyrazolo[3,4-c]pyridine52090-67-2C8H7N3O
- 3,7-Dichloro-1H-pyrazolo[3,4-c]pyridine957760-09-7C6H3Cl2N3
- 5-Bromo-1H-pyrazolo[3,4-c]pyridine929617-35-6C6H4BrN3
- 1 suppliers4-Chloro-1H-pyrazolo[3,4-c]pyridin-3-amine1189727-33-0C6H5ClN4
- 4-Bromo-1H-pyrazolo[3,4-C]pyridine1032943-43-3C6H4BrN3
- 4-Bromo-1H-pyrazolo(3,4-c)pyridin-3-amine870244-35-2C6H5BrN4
- 1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid932702-13-1C7H5N3O2
- 1 suppliersEthyl 1H-pyrazolo[3,4-C]pyridine-3-carboxylate1053656-33-9C9H9N3O2
- 3-Iodo-1H-pyrazolo[3,4-c]pyridine1082040-63-8C6H4IN3
- 7-Hydrazinyl-1H-pyrazolo[3,4-c]pyridine918485-11-7C6H7N5
- 1H-Pyrazolo(3,4-c)pyridin-5-amine1049672-75-4C6H6N4
- 3-Bromo-7-chloro-1H-pyrazolo[3,4-c]pyridine957760-22-4C6H3BrClN3
- 5-Bromo-7-chloro-1H-pyrazolo[3,4-c]pyridine1416374-15-6C6H3BrClN3
- 7-Methoxy-4-nitro-1H-pyrazolo[3,4-c]pyridine1416374-56-5C7H6N4O3
- 2-(4-Bromo-pyrazolo[3,4-c]pyridin-1-yl)-ethanol1032943-42-2C8H8BrN3O
- 4-Bromo-1-(2-methoxy-ethyl)-1H-pyrazolo[3,4-c]pyridine1033532-59-0C9H10BrN3O
- 4-Bromo-1-ethyl-1H-pyrazolo[3,4-c]pyridine1033532-57-8C8H8BrN3
- 4-Bromo-1-(2-methanesulfonyl-ethyl)-1H-pyrazolo[3,4-c]pyridine1033532-63-6C9H10BrN3O2S
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1ccc2[nH]ccc2c1](/scaffold/SIKJAQJRHWYJAI-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]ccc2c12,455 chemicals![Scaffold c1ccc2[nH]cnc2c1](/scaffold/HYZJCKYKOHLVJF-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]cnc2c11,206 chemicals![Scaffold c1ccc2[nH]ncc2c1](/scaffold/BAXOFTOLAUCFNW-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]ncc2c1795 chemicals
c1ccc2scnc2c1756 chemicals
c1ccc2occc2c1632 chemicals
c1ccc2c(c1)CCC2621 chemicals
c1ccc2c(c1)OCO2536 chemicals
c1ccc2sccc2c1529 chemicals
c1ccn2ccnc2c1525 chemicals
c1ccc2c(c1)CCN2440 chemicals![Scaffold O=c1[nH]c(=O)c2[nH]cnc2[nH]1](/scaffold/LRFVTYWOQMYALW-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]cnc2[nH]1411 chemicals
O=C1NC(=O)c2ccccc21352 chemicals