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Murcko scaffold

4H,5H,6H-Cyclopenta[b]thiophen-4-one scaffold

11 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
11
With full pages
5
Scaffold SMILES

O=C1CCc2sccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4H,5H,6H-Cyclopenta[b]thiophen-4-one page
Murcko scaffold O=C1CCc2sccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

5-((Dimethylamino)methyl)-5-methyl-5,6-dihydro-4H-cyclopenta(b)thiophen-4-one chemical structure, C11H15NOS, CAS 93480-76-3
5-((Dimethylamino)methyl)-5-methyl-5,6-dihydro-4H-cyclopenta(b)thiophen-4-one
CAS 93480-76-3C11H15NOS
4H,5H,6H-Cyclopenta[b]thiophen-4-one chemical structure, C7H6OS, CAS 5650-51-1
4H,5H,6H-Cyclopenta[b]thiophen-4-one
CAS 5650-51-1C7H6OS
2-Methyl-4H,5H,6H-cyclopenta[b]thiophen-4-one chemical structure, C8H8OS, CAS 67838-96-4
2-Methyl-4H,5H,6H-cyclopenta[b]thiophen-4-one
CAS 67838-96-4C8H8OS
2-Chloro-4H,5H,6H-cyclopenta(b)thiophen-4-one chemical structure, C7H5ClOS, CAS 69300-48-7
2-Chloro-4H,5H,6H-cyclopenta(b)thiophen-4-one
CAS 69300-48-7C7H5ClOS
Ethyl 5,5-Dimethyl-4-oxo-5,6-dihydro-4H-cyclopenta[b]thiophene-2-carboxylate chemical structure, C12H14O3S, CAS 1227210-44-7
Ethyl 5,5-Dimethyl-4-oxo-5,6-dihydro-4H-cyclopenta[b]thiophene-2-carboxylate
CAS 1227210-44-7C12H14O3S
4-Oxo-5,6-dihydro-4H-cyclopenta[b]thiophene-2-carboxylic Acid chemical structure, C8H6O3S, CAS 1227210-42-5
4-Oxo-5,6-dihydro-4H-cyclopenta[b]thiophene-2-carboxylic Acid
CAS 1227210-42-5C8H6O3S
5,5-Dimethyl-4-oxo-5,6-dihydro-4H-cyclopenta[b]thiophene-2-carboxylic Acid chemical structure, C10H10O3S, CAS 1227210-45-8
5,5-Dimethyl-4-oxo-5,6-dihydro-4H-cyclopenta[b]thiophene-2-carboxylic Acid
CAS 1227210-45-8C10H10O3S
5,6-Dihydro-4-oxo-4H-cyclopenta[b]thiophene-2-carboxylic acid ethyl ester chemical structure, C10H10O3S, CAS 1227210-43-6
5,6-Dihydro-4-oxo-4H-cyclopenta[b]thiophene-2-carboxylic acid ethyl ester
CAS 1227210-43-6C10H10O3S
3-Methyl-6-(nitromethyl)-5,6-dihydro-4H-cyclopenta[b]thiophen-4-one chemical structure, C9H9NO3S, CAS 1310427-71-4
3-Methyl-6-(nitromethyl)-5,6-dihydro-4H-cyclopenta[b]thiophen-4-one
CAS 1310427-71-4C9H9NO3S
2-Bromo-4H,5H,6H-cyclopenta[b]thiophen-4-one chemical structure, C7H5BrOS, CAS 1369353-77-4
2-Bromo-4H,5H,6H-cyclopenta[b]thiophen-4-one
CAS 1369353-77-4C7H5BrOS
Methyl 4-oxo-4H,5H,6H-cyclopenta[b]thiophene-2-carboxylate chemical structure, C9H8O3S, CAS 2091645-52-0
Methyl 4-oxo-4H,5H,6H-cyclopenta[b]thiophene-2-carboxylate
CAS 2091645-52-0C9H8O3S