CompoundList
Sign in
Murcko scaffold

2,3,5,7A-Tetrahydro-1H-pyrrolizine scaffold

131 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
131
With full pages
44
Scaffold SMILES

C1=CC2CCCN2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,3,5,7A-Tetrahydro-1H-pyrrolizine page
Murcko scaffold C1=CC2CCCN2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 131 chemicals

Heliotron chemical structure, C16H27NO5
Heliotron
C16H27NO5
Retronecine chemical structure, C8H13NO2, CAS 480-85-3
Retronecine
CAS 480-85-3C8H13NO2
Cyanustine chemical structure, C15H26ClNO4, CAS 17958-39-3
Cyanustine
CAS 17958-39-3C15H26ClNO4
Supinine N-oxide chemical structure, C15H25NO5, CAS 24351-90-4
Supinine N-oxide
CAS 24351-90-4C15H25NO5
(1-Hydroxy-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl)methyl 2-hydroxy-2-(1-hydroxyethyl)-3-methylbutanoate--hydrogen chloride (1/1) chemical structure, C15H26ClNO5, CAS 26131-12-4
(1-Hydroxy-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl)methyl 2-hydroxy-2-(1-hydroxyethyl)-3-methylbutanoate--hydrogen chloride (1/1)
CAS 26131-12-4C15H26ClNO5
Heliotrine, 7-acetate chemical structure, C18H29NO6, CAS 26607-98-7
Heliotrine, 7-acetate
CAS 26607-98-7C18H29NO6
Echinatine, N-oxide chemical structure, C15H25NO6, CAS 20267-93-0
Echinatine, N-oxide
CAS 20267-93-0C15H25NO6
Heliotridine, 7,9-di-n-valerate chemical structure, C18H29NO4, CAS 59532-52-4
Heliotridine, 7,9-di-n-valerate
CAS 59532-52-4C18H29NO4
Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, (2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl)methyl ester, hydrochloride, (7aS-(7(2R*,3S*),7aR*))- chemical structure, C15H26ClNO4, CAS 106455-44-1
Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, (2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl)methyl ester, hydrochloride, (7aS-(7(2R*,3S*),7aR*))-
CAS 106455-44-1C15H26ClNO4
Retronecine hydrochloride chemical structure, C8H14ClNO2, CAS 875-22-9
Retronecine hydrochloride
CAS 875-22-9C8H14ClNO2
Indicine chemical structure, C15H25NO5, CAS 480-82-0
Indicine
CAS 480-82-0C15H25NO5
(+)-Lycopsamine chemical structure, C15H25NO5, CAS 10285-07-1
(+)-Lycopsamine
CAS 10285-07-1C15H25NO5
Supinine chemical structure, C15H25NO4, CAS 551-58-6
Supinine
CAS 551-58-6C15H25NO4
(+)-Intermedine chemical structure, C15H25NO5, CAS 10285-06-0
(+)-Intermedine
CAS 10285-06-0C15H25NO5
[7-(2-Methylbut-2-enoyloxy)-4-oxido-5,6,7,8-tetrahydro-3H-pyrrolizin-4-ium-1-yl]methyl 2,3-dihydroxy-2-(1-methoxyethyl)-3-methylbutanoate chemical structure, C21H33NO8
[7-(2-Methylbut-2-enoyloxy)-4-oxido-5,6,7,8-tetrahydro-3H-pyrrolizin-4-ium-1-yl]methyl 2,3-dihydroxy-2-(1-methoxyethyl)-3-methylbutanoate
C21H33NO8
7-Acetyllycopsamine chemical structure, C17H27NO6, CAS 73544-48-6
7-Acetyllycopsamine
CAS 73544-48-6C17H27NO6
Uplandicine chemical structure, C17H27NO7, CAS 74202-10-1
Uplandicine
CAS 74202-10-1C17H27NO7
Pentanoic acid, 2-hydroxy-2-(1-hydroxyethyl)-3-methyl-, (2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl)methyl ester chemical structure, C16H27NO4, CAS 84306-92-3
Pentanoic acid, 2-hydroxy-2-(1-hydroxyethyl)-3-methyl-, (2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl)methyl ester
CAS 84306-92-3C16H27NO4
(7aS)-2,3,5,7a-Tetrahydro-1H-pyrrolizine-7-methanol chemical structure, C8H13NO, CAS 551-59-7
(7aS)-2,3,5,7a-Tetrahydro-1H-pyrrolizine-7-methanol
CAS 551-59-7C8H13NO
Retronecine 7,9-isovalerate diester chemical structure, C18H29NO4, CAS 14933-88-1
Retronecine 7,9-isovalerate diester
CAS 14933-88-1C18H29NO4
Retronecine, bis(3-methylcrotonate) (ester) chemical structure, C18H25NO4, CAS 25471-37-8
Retronecine, bis(3-methylcrotonate) (ester)
CAS 25471-37-8C18H25NO4
Uluganine chemical structure, C20H33NO7, CAS 55437-97-3
Uluganine
CAS 55437-97-3C20H33NO7
7-Acetylrinderine chemical structure, C17H27NO6, CAS 56317-18-1
7-Acetylrinderine
CAS 56317-18-1C17H27NO6
5,6,7,8-Tetrahydro-3H-pyrrolizin-1-ylmethanol chemical structure, C8H13NO, CAS 23185-51-5
5,6,7,8-Tetrahydro-3H-pyrrolizin-1-ylmethanol
CAS 23185-51-5C8H13NO