Murcko scaffold
Ring system with 2 rings and 12 atoms
32 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 12
- Chemicals
- 32
- With full pages
- 6
Scaffold SMILES
c1ccc(Sc2ccco2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 32 of 32 chemicals
![N-[4-(5-Nitrofuran-2-yl)sulfanylphenyl]acetamide chemical structure, C12H10N2O4S, CAS 6277-55-0](/s/NPAJZEQRHDGSIE-UHFFFAOYSA-N.svg)
N-[4-(5-Nitrofuran-2-yl)sulfanylphenyl]acetamide
CAS 6277-55-0C12H10N2O4S
![2-Nitro-5-[(4-nitrophenyl)sulfanyl]furan chemical structure, C10H6N2O5S, CAS 6277-16-3](/s/PIEVMGDPUYKMOP-UHFFFAOYSA-N.svg)
2-Nitro-5-[(4-nitrophenyl)sulfanyl]furan
CAS 6277-16-3C10H6N2O5S
![5-[(4-Methylphenyl)thio]-2-furaldehyde chemical structure, C12H10O2S, CAS 56656-92-9](/s/RQCQYRQPIGDHKV-UHFFFAOYSA-N.svg)
5-[(4-Methylphenyl)thio]-2-furaldehyde
CAS 56656-92-9C12H10O2S
5-(Phenylsulfanyl)-2-furaldehyde
CAS 39689-03-7C11H8O2S
RefChem:382136
CAS 56656-64-5C14H8N2OS
![4-Bromo-5-[(4-chlorophenyl)thio]-2-furaldehyde chemical structure, C11H6BrClO2S, CAS 425681-51-2](/s/YIZIACLVSUPZNV-UHFFFAOYSA-N.svg)
4-Bromo-5-[(4-chlorophenyl)thio]-2-furaldehyde
CAS 425681-51-2C11H6BrClO2S
![4-Bromo-5-[(4-methylphenyl)thio]-2-furaldehyde chemical structure, C12H9BrO2S, CAS 597545-05-6](/s/DISPPBMPQGHDDM-UHFFFAOYSA-N.svg)
4-Bromo-5-[(4-methylphenyl)thio]-2-furaldehyde
CAS 597545-05-6C12H9BrO2S
![3-Bromo-2-(4-chlorophenyl)sulfanyl-5-[(E)-2-nitroethenyl]furan chemical structure, C12H7BrClNO3S, CAS 444676-16-8](/s/DAKRRRQYLCSODL-AATRIKPKSA-N.svg)
3-Bromo-2-(4-chlorophenyl)sulfanyl-5-[(E)-2-nitroethenyl]furan
CAS 444676-16-8C12H7BrClNO3S
5-(Phenylthio)furan-2-carboxylic acid
CAS 61942-18-5C11H8O3S
![5-[(4-Chlorophenyl)sulfanyl]-2-furaldehyde chemical structure, C11H7ClO2S, CAS 39689-04-8](/s/HVUPEZXYRPDLNI-UHFFFAOYSA-N.svg)
5-[(4-Chlorophenyl)sulfanyl]-2-furaldehyde
CAS 39689-04-8C11H7ClO2S
![N-[(E)-[5-(4-Methylphenyl)sulfanylfuran-2-yl]methylideneamino]acetamide chemical structure, C14H14N2O2S, CAS 301202-98-2](/s/CKRRKMZEQGTJKB-OQLLNIDSSA-N.svg)
N-[(E)-[5-(4-Methylphenyl)sulfanylfuran-2-yl]methylideneamino]acetamide
CAS 301202-98-2C14H14N2O2S
![5-[(4-Bromophenyl)sulfanyl]-2-furaldehyde chemical structure, C11H7BrO2S, CAS 56656-94-1](/s/OPRPLUWSLMRQRM-UHFFFAOYSA-N.svg)
5-[(4-Bromophenyl)sulfanyl]-2-furaldehyde
CAS 56656-94-1C11H7BrO2S
![2-[(4-Bromophenyl)thio]furan chemical structure, C10H7BrOS, CAS 53906-94-8](/s/LQQWNXYSHVVAAT-UHFFFAOYSA-N.svg)
2-[(4-Bromophenyl)thio]furan
CAS 53906-94-8C10H7BrOS
![({5-[(4-Methylphenyl)sulfanyl]furan-2-yl}methylidene)propanedinitrile chemical structure, C15H10N2OS, CAS 56656-65-6](/s/QURIVBZCIDVFLD-UHFFFAOYSA-N.svg)
({5-[(4-Methylphenyl)sulfanyl]furan-2-yl}methylidene)propanedinitrile
CAS 56656-65-6C15H10N2OS
![5-[(4-Methoxyphenyl)thio]-2-furancarboxaldehyde chemical structure, C12H10O3S, CAS 56656-93-0](/s/RUIBKLCHSXVKDX-UHFFFAOYSA-N.svg)
5-[(4-Methoxyphenyl)thio]-2-furancarboxaldehyde
CAS 56656-93-0C12H10O3S
5-((4-Chlorophenyl)sulfanyl)furan-2-carboxylic acid
CAS 61942-22-1C11H7ClO3S
![[2-(Phenylsulfanyl)furan-3-yl]methanol chemical structure, C11H10O2S, CAS 89861-09-6](/s/JLPFWJSPBKXFST-UHFFFAOYSA-N.svg)
[2-(Phenylsulfanyl)furan-3-yl]methanol
CAS 89861-09-6C11H10O2S
![tert-Butyl(dimethyl){[2-(phenylsulfanyl)furan-3-yl]methoxy}silane chemical structure, C17H24O2SSi, CAS 89861-10-9](/s/SELMUCDYMDFNCJ-UHFFFAOYSA-N.svg)
tert-Butyl(dimethyl){[2-(phenylsulfanyl)furan-3-yl]methoxy}silane
CAS 89861-10-9C17H24O2SSi
![2-[2-(Phenylsulfanyl)furan-3-yl]ethan-1-ol chemical structure, C12H12O2S, CAS 89861-16-5](/s/XZZXDXIINLTMRC-UHFFFAOYSA-N.svg)
2-[2-(Phenylsulfanyl)furan-3-yl]ethan-1-ol
CAS 89861-16-5C12H12O2S
![Trimethyl{2-[2-(phenylsulfanyl)-5-(trimethylsilyl)furan-3-yl]ethoxy}silane chemical structure, C18H28O2SSi2, CAS 89861-17-6](/s/NJCXIKZTMYQPIS-UHFFFAOYSA-N.svg)
Trimethyl{2-[2-(phenylsulfanyl)-5-(trimethylsilyl)furan-3-yl]ethoxy}silane
CAS 89861-17-6C18H28O2SSi2
3-Methyl-2-(phenylsulfanyl)furan
CAS 90141-37-0C11H10OS
![5-[(2,4-Dinitrophenyl)sulfanyl]furan-2-carbonitrile chemical structure, C11H5N3O5S, CAS 106240-51-1](/s/MWIKYCFUKQGGIT-UHFFFAOYSA-N.svg)
5-[(2,4-Dinitrophenyl)sulfanyl]furan-2-carbonitrile
CAS 106240-51-1C11H5N3O5S
Methyl 5-(p-tolylthio)furan-2-carboxylate
CAS 93104-99-5C13H12O3S
![5-[(4-Methylphenyl)sulfanyl]furan-2-carbonitrile chemical structure, C12H9NOS, CAS 93104-65-5](/s/XIEFSPZFPAGTTI-UHFFFAOYSA-N.svg)
5-[(4-Methylphenyl)sulfanyl]furan-2-carbonitrile
CAS 93104-65-5C12H9NOS
- 5-[(2-Chlorophenyl)thio]-2-furylaldehyde639517-98-9C11H7ClO2S
- 5-[(4-Fluorophenyl)sulfanyl]furan-2-carbaldehyde115192-43-3C11H7FO2S
- 5-(Phenylthio)-2-furansulfonyl chloride166964-27-8C10H7ClO3S2
- 1-(5-(Phenylthio)-2-furyl)ethanone28569-36-0C12H10O2S
- 2-tert-Butyl-5-(phenylthio)furan941270-60-6C14H16OS
- Methyl 4-bromo-5-(phenylthio)furan-2-carboxylate1403564-92-0C12H9BrO3S
- (3R)-3-Amino-3-[5-(phenylsulfanyl)furan-2-yl]propanoic acid1270272-66-6C13H13NO3S
- 2-((4-Methoxyphenyl)thio)furan2476701-38-7C11H10O2S
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(Cn2cccn2)cc1271 chemicals
c1ccc(CN2CCCC2)cc1172 chemicals
O=S(=O)(c1ccccc1)N1CCCC1146 chemicals
c1ccc(Cn2ccnc2)cc1107 chemicals![Scaffold c1ccc(N=c2[nH]ccs2)cc1](/scaffold/OGVGQYZRJXSMGC-UHFFFAOYSA-N/structure.svg)
c1ccc(N=c2[nH]ccs2)cc198 chemicals
O=C1NC(=S)SC1=Cc1ccccc186 chemicals
O=C(c1ccccc1)N1CCCC186 chemicals
O=S(=O)(c1ccccc1)n1ccnc184 chemicals![Scaffold O=C(c1ccccc1)c1cc[nH]c1](/scaffold/DSNSKSWTLGZGAN-UHFFFAOYSA-N/structure.svg)
O=C(c1ccccc1)c1cc[nH]c177 chemicals
c1ccc(Cn2ccnn2)cc177 chemicals
c1ccc(Cc2cncs2)cc175 chemicals
c1ccc(Cn2cccc2)cc163 chemicals