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Murcko scaffold

Ring system with 2 rings and 15 atoms

6 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
6
With full pages
1
Scaffold SMILES

O=C(Nc1cccnc1)c1cnccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cccnc1)c1cnccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

3-Amino-6-bromo-N-pyridin-3-ylpyrazine-2-carboxamide chemical structure, C10H8BrN5O, CAS 486422-03-1
3-Amino-6-bromo-N-pyridin-3-ylpyrazine-2-carboxamide
CAS 486422-03-1C10H8BrN5O
Acdpp hydrochloride chemical structure, C12H14Cl2N6O, CAS 37804-11-8
Acdpp hydrochloride
CAS 37804-11-8C12H14Cl2N6O
Acdpp chemical structure, C12H13ClN6O, CAS 1178093-95-2
Acdpp
CAS 1178093-95-2C12H13ClN6O
3-Amino-N-(4-chloro-3-pyridinyl)-2-pyrazinecarboxamide chemical structure, C10H8ClN5O, CAS 1052706-15-6
3-Amino-N-(4-chloro-3-pyridinyl)-2-pyrazinecarboxamide
CAS 1052706-15-6C10H8ClN5O
6-Methyl-N-(4-methylpyridin-3-yl)pyrazine-2-carboxamide chemical structure, C12H12N4O, CAS 2415634-17-0
6-Methyl-N-(4-methylpyridin-3-yl)pyrazine-2-carboxamide
CAS 2415634-17-0C12H12N4O
N-(6-Methoxypyridin-3-yl)-6-methylpyrazine-2-carboxamide chemical structure, C12H12N4O2, CAS 2415454-61-2
N-(6-Methoxypyridin-3-yl)-6-methylpyrazine-2-carboxamide
CAS 2415454-61-2C12H12N4O2