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Murcko scaffold

Furo(2,3-d)pyrimidine scaffold

90 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
90
With full pages
10
Scaffold SMILES

c1ncc2ccoc2n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Furo(2,3-d)pyrimidine page
Murcko scaffold c1ncc2ccoc2n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 90 chemicals

5,6-Dimethylfuro[2,3-d]pyrimidin-4-amine chemical structure, C8H9N3O, CAS 5117-94-2
5,6-Dimethylfuro[2,3-d]pyrimidin-4-amine
CAS 5117-94-2C8H9N3O
4,6-Dimethylfuro[2,3-d]pyrimidin-2-amine chemical structure, C8H9N3O, CAS 22727-43-1
4,6-Dimethylfuro[2,3-d]pyrimidin-2-amine
CAS 22727-43-1C8H9N3O
4,6-Dimethyl-2-(methylsulfanyl)furo[2,3-d]pyrimidine chemical structure, C9H10N2OS, CAS 22727-34-0
4,6-Dimethyl-2-(methylsulfanyl)furo[2,3-d]pyrimidine
CAS 22727-34-0C9H10N2OS
4-[(4-Amino-5,6-dimethylfuro[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(3-hydroxypropyl)butanamide chemical structure, C15H22N4O3S, CAS 497081-98-8
4-[(4-Amino-5,6-dimethylfuro[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(3-hydroxypropyl)butanamide
CAS 497081-98-8C15H22N4O3S
2-[(4-Amino-5,6-dimethylfuro[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(2-hydroxyethyl)acetamide chemical structure, C12H16N4O3S, CAS 497081-93-3
2-[(4-Amino-5,6-dimethylfuro[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(2-hydroxyethyl)acetamide
CAS 497081-93-3C12H16N4O3S
2-(4-Amino-5,6-dimethylfuro[2,3-d]pyrimidin-2-yl)sulfanyl-N-(3-hydroxypropyl)acetamide chemical structure, C13H18N4O3S, CAS 497081-95-5
2-(4-Amino-5,6-dimethylfuro[2,3-d]pyrimidin-2-yl)sulfanyl-N-(3-hydroxypropyl)acetamide
CAS 497081-95-5C13H18N4O3S
4-(4-Amino-5,6-dimethylfuro[2,3-d]pyrimidin-2-yl)sulfanyl-N-(2-hydroxyethyl)butanamide chemical structure, C14H20N4O3S, CAS 497081-97-7
4-(4-Amino-5,6-dimethylfuro[2,3-d]pyrimidin-2-yl)sulfanyl-N-(2-hydroxyethyl)butanamide
CAS 497081-97-7C14H20N4O3S
Ethyl 4-amino-2-(chloromethyl)-6-methylfuro[2,3-d]pyrimidine-5-carboxylate chemical structure, C11H12ClN3O3, CAS 796067-48-6
Ethyl 4-amino-2-(chloromethyl)-6-methylfuro[2,3-d]pyrimidine-5-carboxylate
CAS 796067-48-6C11H12ClN3O3
Furo(2,3-d)pyrimidin-4-amine, 2-(ethylthio)-5-methyl-, monohydrobromide chemical structure, C9H12BrN3OS, CAS 66505-62-2
Furo(2,3-d)pyrimidin-4-amine, 2-(ethylthio)-5-methyl-, monohydrobromide
CAS 66505-62-2C9H12BrN3OS
Furo(2,3-d)pyrimidin-4-amine, 5-methyl-2-(methylthio)-, monohydrobromide chemical structure, C8H10BrN3OS, CAS 66505-63-3
Furo(2,3-d)pyrimidin-4-amine, 5-methyl-2-(methylthio)-, monohydrobromide
CAS 66505-63-3C8H10BrN3OS
Furo(2,3-d)pyrimidin-4-amine, 5-methyl-2-(2-propenylthio)- chemical structure, C10H11N3OS, CAS 66505-64-4
Furo(2,3-d)pyrimidin-4-amine, 5-methyl-2-(2-propenylthio)-
CAS 66505-64-4C10H11N3OS
N-(5,6-Dimethylfuro[2,3-d]pyrimidin-4-yl)-N',N'-dimethylpropane-1,3-diamine chemical structure, C13H20N4O, CAS 902027-01-4
N-(5,6-Dimethylfuro[2,3-d]pyrimidin-4-yl)-N',N'-dimethylpropane-1,3-diamine
CAS 902027-01-4C13H20N4O
N-(5,6-Dimethylfuro[2,3-d]pyrimidin-4-yl)-N',N'-diethylpropane-1,3-diamine chemical structure, C15H24N4O, CAS 904262-12-0
N-(5,6-Dimethylfuro[2,3-d]pyrimidin-4-yl)-N',N'-diethylpropane-1,3-diamine
CAS 904262-12-0C15H24N4O
2-[(5,6-Dimethylfuro[2,3-d]pyrimidin-4-yl)amino]ethanol chemical structure, C10H13N3O2, CAS 902035-15-8
2-[(5,6-Dimethylfuro[2,3-d]pyrimidin-4-yl)amino]ethanol
CAS 902035-15-8C10H13N3O2
N-(5,6-Dimethylfuro[2,3-d]pyrimidin-4-yl)-N',N'-diethylethane-1,2-diamine chemical structure, C14H22N4O, CAS 902308-51-4
N-(5,6-Dimethylfuro[2,3-d]pyrimidin-4-yl)-N',N'-diethylethane-1,2-diamine
CAS 902308-51-4C14H22N4O
N-(5,6-Dimethylfuro[2,3-d]pyrimidin-4-yl)-N',N'-dimethylethane-1,2-diamine chemical structure, C12H18N4O, CAS 902326-05-0
N-(5,6-Dimethylfuro[2,3-d]pyrimidin-4-yl)-N',N'-dimethylethane-1,2-diamine
CAS 902326-05-0C12H18N4O
3-[(5,6-Dimethylfuro[2,3-d]pyrimidin-4-yl)amino]propan-1-ol chemical structure, C11H15N3O2, CAS 902333-98-6
3-[(5,6-Dimethylfuro[2,3-d]pyrimidin-4-yl)amino]propan-1-ol
CAS 902333-98-6C11H15N3O2
Furo(2,3-d)pyrimidin-4-amine chemical structure, C6H5N3O, CAS 186454-70-6
Furo(2,3-d)pyrimidin-4-amine
CAS 186454-70-6C6H5N3O
5-Methylfuro[2,3-d]pyrimidine-2,4-diamine chemical structure, C7H8N4O, CAS 67194-84-7
5-Methylfuro[2,3-d]pyrimidine-2,4-diamine
CAS 67194-84-7C7H8N4O
(2-(Methylthio)furo[2,3-d]pyrimidin-6-yl)methanol chemical structure, C8H8N2O2S, CAS 649558-78-1
(2-(Methylthio)furo[2,3-d]pyrimidin-6-yl)methanol
CAS 649558-78-1C8H8N2O2S
Furo[2,3-d]pyrimidine-6-methanol, 2-methoxy-4-methyl- chemical structure, C9H10N2O3, CAS 649558-74-7
Furo[2,3-d]pyrimidine-6-methanol, 2-methoxy-4-methyl-
CAS 649558-74-7C9H10N2O3
5-(Chloromethyl)furo[2,3-d]pyrimidine-2,4-diamine chemical structure, C7H7ClN4O, CAS 67194-86-9
5-(Chloromethyl)furo[2,3-d]pyrimidine-2,4-diamine
CAS 67194-86-9C7H7ClN4O
Methyl 2,4-diaminofuro[2,3-d]pyrimidine-6-carboxylate chemical structure, C8H8N4O3, CAS 124738-77-8
Methyl 2,4-diaminofuro[2,3-d]pyrimidine-6-carboxylate
CAS 124738-77-8C8H8N4O3
4-Chloro-5,6-dimethylfuro[2,3-d]pyrimidine chemical structure, C8H7ClN2O, CAS 139370-57-3
4-Chloro-5,6-dimethylfuro[2,3-d]pyrimidine
CAS 139370-57-3C8H7ClN2O