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Murcko scaffold

Ring system with 3 rings and 17 atoms

173 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
173
With full pages
20
Scaffold SMILES

O=c1c2ccccc2ccn1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c2ccccc2ccn1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 173 of 173 chemicals

2-(2,4-Difluorophenyl)-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid chemical structure, C16H9F2NO3, CAS 3030826-43-5
2-(2,4-Difluorophenyl)-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid
CAS 3030826-43-5C16H9F2NO3
2-(4-Fluorophenyl)-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid chemical structure, C16H10FNO3, CAS 3030868-76-6
2-(4-Fluorophenyl)-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid
CAS 3030868-76-6C16H10FNO3
6,7-Difluoro-2-(4-fluorophenyl)-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid chemical structure, C16H8F3NO3, CAS 3030823-29-8
6,7-Difluoro-2-(4-fluorophenyl)-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid
CAS 3030823-29-8C16H8F3NO3
2-(2,4-Difluorophenyl)-6,7-difluoro-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid chemical structure, C16H7F4NO3, CAS 3030839-04-1
2-(2,4-Difluorophenyl)-6,7-difluoro-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid
CAS 3030839-04-1C16H7F4NO3
1-Oxo-2-phenyl-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C16H12N2O2, CAS 3054551-42-4
1-Oxo-2-phenyl-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054551-42-4C16H12N2O2
N,N-Dimethyl-1-oxo-2-phenyl-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C18H16N2O2, CAS 3054617-40-9
N,N-Dimethyl-1-oxo-2-phenyl-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054617-40-9C18H16N2O2
N-Methyl-1-oxo-2-phenyl-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C17H14N2O2, CAS 3054604-48-4
N-Methyl-1-oxo-2-phenyl-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054604-48-4C17H14N2O2
1-Oxo-2-phenyl-N-(propan-2-yl)-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C19H18N2O2, CAS 3054585-12-2
1-Oxo-2-phenyl-N-(propan-2-yl)-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054585-12-2C19H18N2O2
2-(4-Fluorophenyl)-N,N-dimethyl-1-oxo-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C18H15FN2O2, CAS 3054620-37-7
2-(4-Fluorophenyl)-N,N-dimethyl-1-oxo-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054620-37-7C18H15FN2O2
N-Ethyl-1-oxo-2-phenyl-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C18H16N2O2, CAS 3054621-90-5
N-Ethyl-1-oxo-2-phenyl-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054621-90-5C18H16N2O2
2-(4-Fluorophenyl)-1-oxo-N-(propan-2-yl)-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C19H17FN2O2, CAS 3054586-74-9
2-(4-Fluorophenyl)-1-oxo-N-(propan-2-yl)-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054586-74-9C19H17FN2O2
N-Ethyl-2-(4-fluorophenyl)-1-oxo-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C18H15FN2O2, CAS 3054604-72-4
N-Ethyl-2-(4-fluorophenyl)-1-oxo-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054604-72-4C18H15FN2O2
1-Oxo-2-phenyl-N-(2,2,2-trifluoroethyl)-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C18H13F3N2O2, CAS 3054621-74-5
1-Oxo-2-phenyl-N-(2,2,2-trifluoroethyl)-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054621-74-5C18H13F3N2O2
2-(4-Fluorophenyl)-1-oxo-N-(2,2,2-trifluoroethyl)-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C18H12F4N2O2, CAS 3054622-85-1
2-(4-Fluorophenyl)-1-oxo-N-(2,2,2-trifluoroethyl)-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054622-85-1C18H12F4N2O2
N,N-Diethyl-1-oxo-2-phenyl-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C20H20N2O2, CAS 3054569-32-0
N,N-Diethyl-1-oxo-2-phenyl-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054569-32-0C20H20N2O2
1-Oxo-2-phenyl-N-(prop-2-en-1-yl)-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C19H16N2O2, CAS 3054622-69-1
1-Oxo-2-phenyl-N-(prop-2-en-1-yl)-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054622-69-1C19H16N2O2
N,N-Diethyl-2-(4-fluorophenyl)-1-oxo-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C20H19FN2O2, CAS 3054415-88-9
N,N-Diethyl-2-(4-fluorophenyl)-1-oxo-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054415-88-9C20H19FN2O2
2-(4-Fluorophenyl)-1-oxo-N-(prop-2-en-1-yl)-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C19H15FN2O2, CAS 3054554-34-3
2-(4-Fluorophenyl)-1-oxo-N-(prop-2-en-1-yl)-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054554-34-3C19H15FN2O2
1-Oxo-2-phenyl-1,2-dihydroisoquinoline-3-carboxylic acid chemical structure, C16H11NO3, CAS 412336-51-7
1-Oxo-2-phenyl-1,2-dihydroisoquinoline-3-carboxylic acid
CAS 412336-51-7C16H11NO3
1-Oxo-2-phenyl-N-propyl-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C19H18N2O2, CAS 3054595-28-4
1-Oxo-2-phenyl-N-propyl-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054595-28-4C19H18N2O2
2-(4-Fluorophenyl)-1-oxo-N-propyl-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C19H17FN2O2, CAS 3054584-06-1
2-(4-Fluorophenyl)-1-oxo-N-propyl-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054584-06-1C19H17FN2O2
2-(4-Fluorophenyl)-1-oxo-N-(prop-2-yn-1-yl)-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C19H13FN2O2, CAS 3054630-40-6
2-(4-Fluorophenyl)-1-oxo-N-(prop-2-yn-1-yl)-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054630-40-6C19H13FN2O2
N-Methoxy-N-methyl-1-oxo-2-phenyl-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C18H16N2O3, CAS 3054558-95-8
N-Methoxy-N-methyl-1-oxo-2-phenyl-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054558-95-8C18H16N2O3
2-(4-Fluorophenyl)-N-methoxy-N-methyl-1-oxo-1,2-dihydroisoquinoline-3-carboxamide chemical structure, C18H15FN2O3, CAS 3054562-67-0
2-(4-Fluorophenyl)-N-methoxy-N-methyl-1-oxo-1,2-dihydroisoquinoline-3-carboxamide
CAS 3054562-67-0C18H15FN2O3