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Murcko scaffold

Ring system with 2 rings and 10 atoms

71 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
71
With full pages
3
Scaffold SMILES

O=S1(=O)C2CCCC1CC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S1(=O)C2CCCC1CC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 71 chemicals

rac-(1R,3R,5S)-8,8-Dioxo-8lambda6-thiabicyclo(3.2.1)octane-3-carboxylic acid chemical structure, C8H12O4S, CAS 2089246-26-2
rac-(1R,3R,5S)-8,8-Dioxo-8lambda6-thiabicyclo(3.2.1)octane-3-carboxylic acid
CAS 2089246-26-2C8H12O4S
8,8-Dioxo-8lambda6-thiabicyclo[3.2.1]octane-3-carboxylic acid chemical structure, C8H12O4S, CAS 2094523-87-0
8,8-Dioxo-8lambda6-thiabicyclo[3.2.1]octane-3-carboxylic acid
CAS 2094523-87-0C8H12O4S
3-Hydroxy-8lambda6-thiabicyclo[3.2.1]octane-8,8-dione chemical structure, C7H12O3S, CAS 2094363-16-1
3-Hydroxy-8lambda6-thiabicyclo[3.2.1]octane-8,8-dione
CAS 2094363-16-1C7H12O3S
3-(Aminomethyl)-8lambda6-thiabicyclo[3.2.1]octane-8,8-dione hydrochloride chemical structure, C8H16ClNO2S, CAS 2094866-34-7
3-(Aminomethyl)-8lambda6-thiabicyclo[3.2.1]octane-8,8-dione hydrochloride
CAS 2094866-34-7C8H16ClNO2S
3-Amino-8lambda6-thiabicyclo[3.2.1]octane-8,8-dione chemical structure, C7H13NO2S, CAS 1935372-43-2
3-Amino-8lambda6-thiabicyclo[3.2.1]octane-8,8-dione
CAS 1935372-43-2C7H13NO2S
3-Amino-8lambda6-thiabicyclo[3.2.1]octane-8,8-dione hydrochloride chemical structure, C7H14ClNO2S, CAS 2126162-54-5
3-Amino-8lambda6-thiabicyclo[3.2.1]octane-8,8-dione hydrochloride
CAS 2126162-54-5C7H14ClNO2S
3-(Hydroxymethyl)-8lambda6-thiabicyclo[3.2.1]octane-8,8-dione chemical structure, C8H14O3S, CAS 2137631-00-4
3-(Hydroxymethyl)-8lambda6-thiabicyclo[3.2.1]octane-8,8-dione
CAS 2137631-00-4C8H14O3S
3-Methyl-8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octane-3-carboxylic acid chemical structure, C9H14O4S, CAS 2138112-79-3
3-Methyl-8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octane-3-carboxylic acid
CAS 2138112-79-3C9H14O4S
N-({8,8-Dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}methyl)prop-2-enamide chemical structure, C11H17NO3S, CAS 2361656-16-6
N-({8,8-Dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}methyl)prop-2-enamide
CAS 2361656-16-6C11H17NO3S
3-({8,8-Dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}carbamoyl)propanoic acid chemical structure, C11H17NO5S, CAS 2137799-00-7
3-({8,8-Dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}carbamoyl)propanoic acid
CAS 2137799-00-7C11H17NO5S
4-({8,8-Dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}carbamoyl)-3-methylbutanoic acid chemical structure, C13H21NO5S, CAS 2137840-94-7
4-({8,8-Dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}carbamoyl)-3-methylbutanoic acid
CAS 2137840-94-7C13H21NO5S
5-Chloro-N-{8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}pentanamide chemical structure, C12H20ClNO3S, CAS 2137799-01-8
5-Chloro-N-{8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}pentanamide
CAS 2137799-01-8C12H20ClNO3S
3-Chloro-N-{8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}-2,2-dimethylpropanamide chemical structure, C12H20ClNO3S, CAS 2137841-01-9
3-Chloro-N-{8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}-2,2-dimethylpropanamide
CAS 2137841-01-9C12H20ClNO3S
2-[({8,8-Dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}carbamoyl)methoxy]acetic acid chemical structure, C11H17NO6S, CAS 2137747-07-8
2-[({8,8-Dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}carbamoyl)methoxy]acetic acid
CAS 2137747-07-8C11H17NO6S
4-({8,8-Dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}carbamoyl)butanoic acid chemical structure, C12H19NO5S, CAS 2137656-28-9
4-({8,8-Dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}carbamoyl)butanoic acid
CAS 2137656-28-9C12H19NO5S
Ethyl ({8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}carbamoyl)formate chemical structure, C11H17NO5S, CAS 2137747-32-9
Ethyl ({8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}carbamoyl)formate
CAS 2137747-32-9C11H17NO5S
2-Bromo-N-{8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}acetamide chemical structure, C9H14BrNO3S, CAS 2137747-33-0
2-Bromo-N-{8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}acetamide
CAS 2137747-33-0C9H14BrNO3S
4-Chloro-N-{8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}butanamide chemical structure, C11H18ClNO3S, CAS 2137844-39-2
4-Chloro-N-{8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}butanamide
CAS 2137844-39-2C11H18ClNO3S
5-Bromo-N-{8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}pentanamide chemical structure, C12H20BrNO3S, CAS 2138170-13-3
5-Bromo-N-{8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}pentanamide
CAS 2138170-13-3C12H20BrNO3S
2-Chloro-N-{8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}propanamide chemical structure, C10H16ClNO3S, CAS 2138217-03-3
2-Chloro-N-{8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}propanamide
CAS 2138217-03-3C10H16ClNO3S
Ethyl 2-({8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}carbamoyl)acetate chemical structure, C12H19NO5S, CAS 2137844-45-0
Ethyl 2-({8,8-dioxo-8lambda6-thiabicyclo[3.2.1]octan-3-yl}carbamoyl)acetate
CAS 2137844-45-0C12H19NO5S
3-(Propylamino)-8lambda6-thiabicyclo[3.2.1]octane-8,8-dione chemical structure, C10H19NO2S, CAS 2137776-94-2
3-(Propylamino)-8lambda6-thiabicyclo[3.2.1]octane-8,8-dione
CAS 2137776-94-2C10H19NO2S
3-[(2-Methylpropyl)amino]-8lambda6-thiabicyclo[3.2.1]octane-8,8-dione chemical structure, C11H21NO2S, CAS 2137776-96-4
3-[(2-Methylpropyl)amino]-8lambda6-thiabicyclo[3.2.1]octane-8,8-dione
CAS 2137776-96-4C11H21NO2S
3-(Bromomethyl)-8lambda6-thiabicyclo[3.2.1]octane-8,8-dione chemical structure, C8H13BrO2S, CAS 2137717-41-8
3-(Bromomethyl)-8lambda6-thiabicyclo[3.2.1]octane-8,8-dione
CAS 2137717-41-8C8H13BrO2S