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Murcko scaffold

Ring system with 4 rings and 24 atoms

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
14
With full pages
3
Scaffold SMILES

O=C1C=CC(=O)c2nc(-c3cc(-c4ccccc4)ccn3)ccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=CC(=O)c2nc(-c3cc(-c4ccccc4)ccn3)ccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

Streptonigrin chemical structure, C25H22N4O8, CAS 3930-19-6
Streptonigrin
CAS 3930-19-6C25H22N4O8
Methyl 5-amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl-2-pyridinecarboxylate chemical structure, C26H24N4O8, CAS 3398-48-9
Methyl 5-amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl-2-pyridinecarboxylate
CAS 3398-48-9C26H24N4O8
10'-O-Demethylstreptonigrin chemical structure, C24H20N4O8, CAS 105933-56-0
10'-O-Demethylstreptonigrin
CAS 105933-56-0C24H20N4O8
10'-Desmethoxystreptonigrin chemical structure, C24H20N4O7, CAS 136803-89-9
10'-Desmethoxystreptonigrin
CAS 136803-89-9C24H20N4O7
2'-Decarboxy-2'-aminostreptonigrin chemical structure, C24H23N5O6, CAS 143139-76-8
2'-Decarboxy-2'-aminostreptonigrin
CAS 143139-76-8C24H23N5O6
Streptonigrin amide chemical structure, C25H23N5O7, CAS 99520-46-4
Streptonigrin amide
CAS 99520-46-4C25H23N5O7
Streptonigrin carboxamidoethanol chemical structure, C27H27N5O8, CAS 99520-45-3
Streptonigrin carboxamidoethanol
CAS 99520-45-3C27H27N5O8
2-Pyridinecarboxamide, 5-amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-N-(3-(dimethylamino)propyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl- chemical structure, C30H34N6O7, CAS 99520-44-2
2-Pyridinecarboxamide, 5-amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-N-(3-(dimethylamino)propyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl-
CAS 99520-44-2C30H34N6O7
Streptonigrin carboxamidoacetic acid chemical structure, C27H25N5O9, CAS 99533-82-1
Streptonigrin carboxamidoacetic acid
CAS 99533-82-1C27H25N5O9
di-2',8'-O-di-5',5'-N,N-Methylstreptonigrone chemical structure, C28H30N4O7, CAS 140458-71-5
di-2',8'-O-di-5',5'-N,N-Methylstreptonigrone
CAS 140458-71-5C28H30N4O7
7-(1-Methyl-2-oxopropyl)streptonigrin chemical structure, C29H28N4O9, CAS 436142-66-4
7-(1-Methyl-2-oxopropyl)streptonigrin
CAS 436142-66-4C29H28N4O9
Stn-nhnhconh2 chemical structure, C26H25N7O8, CAS 99520-40-8
Stn-nhnhconh2
CAS 99520-40-8C26H25N7O8
4-[[[5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl-2-pyridinyl]carbonyl]amino]butanoic acid chemical structure, C29H29N5O9, CAS 122547-53-9
4-[[[5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl-2-pyridinyl]carbonyl]amino]butanoic acid
CAS 122547-53-9C29H29N5O9
5-Amino-6-(6-amino-5,8-dihydro-7-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl-2-pyridinecarboxylic acid chemical structure, C25H22N4O8, CAS 632-62-2
5-Amino-6-(6-amino-5,8-dihydro-7-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl-2-pyridinecarboxylic acid
CAS 632-62-2C25H22N4O8