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Murcko scaffold

2-[3-(4-Benzylpiperazin-1-yl)-3-oxopropyl]isoindole-1,3-dione scaffold

3 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
3
With full pages
3
Scaffold SMILES

O=C(CCN1C(=O)c2ccccc2C1=O)N1CCN(Cc2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-[3-(4-Benzylpiperazin-1-yl)-3-oxopropyl]isoindole-1,3-dione page
Murcko scaffold O=C(CCN1C(=O)c2ccccc2C1=O)N1CCN(Cc2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 3 of 3 chemicals

2-[3-(4-Benzylpiperazin-1-yl)-3-oxopropyl]isoindole-1,3-dione chemical structure, C22H23N3O3, CAS 331870-14-5
2-[3-(4-Benzylpiperazin-1-yl)-3-oxopropyl]isoindole-1,3-dione
CAS 331870-14-5C22H23N3O3
2-[3-[4-[(2,4-Dichlorophenyl)methyl]piperazin-1-yl]-3-oxopropyl]isoindole-1,3-dione chemical structure, C22H21Cl2N3O3, CAS 421572-96-5
2-[3-[4-[(2,4-Dichlorophenyl)methyl]piperazin-1-yl]-3-oxopropyl]isoindole-1,3-dione
CAS 421572-96-5C22H21Cl2N3O3
2-[3-[4-[(4-Methylphenyl)methyl]piperazin-1-yl]-3-oxopropyl]isoindole-1,3-dione chemical structure, C23H25N3O3, CAS 312525-86-3
2-[3-[4-[(4-Methylphenyl)methyl]piperazin-1-yl]-3-oxopropyl]isoindole-1,3-dione
CAS 312525-86-3C23H25N3O3