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Murcko scaffold

Ring system with 4 rings and 28 atoms

65 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
65
With full pages
5
Scaffold SMILES

O=C(NN=c1[nH]c2ccccc2s1)c1ccc(S(=O)(=O)N2CCCCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=c1[nH]c2ccccc2s1)c1ccc(S(=O)(=O)N2CCCCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 65 chemicals

(Z)-N'-(3-Methylbenzo[d]thiazol-2(3H)-ylidene)-4-(piperidin-1-ylsulfonyl)benzohydrazide chemical structure, C20H22N4O3S2, CAS 302939-20-4
(Z)-N'-(3-Methylbenzo[d]thiazol-2(3H)-ylidene)-4-(piperidin-1-ylsulfonyl)benzohydrazide
CAS 302939-20-4C20H22N4O3S2
N'-(4,6-Dimethyl-1,3-benzothiazol-2-yl)-4-(piperidine-1-sulfonyl)benzohydrazide chemical structure, C21H24N4O3S2, CAS 851987-20-7
N'-(4,6-Dimethyl-1,3-benzothiazol-2-yl)-4-(piperidine-1-sulfonyl)benzohydrazide
CAS 851987-20-7C21H24N4O3S2
N'-(4,6-Dimethylbenzo[d]thiazol-2-yl)-4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzohydrazide chemical structure, C23H28N4O3S2, CAS 851987-30-9
N'-(4,6-Dimethylbenzo[d]thiazol-2-yl)-4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzohydrazide
CAS 851987-30-9C23H28N4O3S2
N'-(4-Methylbenzo[d]thiazol-2-yl)-4-((3-methylpiperidin-1-yl)sulfonyl)benzohydrazide chemical structure, C21H24N4O3S2, CAS 851978-06-8
N'-(4-Methylbenzo[d]thiazol-2-yl)-4-((3-methylpiperidin-1-yl)sulfonyl)benzohydrazide
CAS 851978-06-8C21H24N4O3S2
4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-N'-(4-methylbenzo[d]thiazol-2-yl)benzohydrazide chemical structure, C22H26N4O3S2, CAS 851978-00-2
4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-N'-(4-methylbenzo[d]thiazol-2-yl)benzohydrazide
CAS 851978-00-2C22H26N4O3S2
N'-(4,6-Dimethylbenzo[d]thiazol-2-yl)-4-((3-methylpiperidin-1-yl)sulfonyl)benzohydrazide chemical structure, C22H26N4O3S2, CAS 851987-36-5
N'-(4,6-Dimethylbenzo[d]thiazol-2-yl)-4-((3-methylpiperidin-1-yl)sulfonyl)benzohydrazide
CAS 851987-36-5C22H26N4O3S2
4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-N'-(4-methoxybenzo[d]thiazol-2-yl)benzohydrazide chemical structure, C22H26N4O4S2, CAS 851978-37-5
4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-N'-(4-methoxybenzo[d]thiazol-2-yl)benzohydrazide
CAS 851978-37-5C22H26N4O4S2
N'-(4-Chlorobenzo[d]thiazol-2-yl)-4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzohydrazide chemical structure, C21H23ClN4O3S2, CAS 851979-23-2
N'-(4-Chlorobenzo[d]thiazol-2-yl)-4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzohydrazide
CAS 851979-23-2C21H23ClN4O3S2
N'-(4-Chlorobenzo[d]thiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzohydrazide chemical structure, C20H21ClN4O3S2, CAS 851979-29-8
N'-(4-Chlorobenzo[d]thiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzohydrazide
CAS 851979-29-8C20H21ClN4O3S2
N'-(4-Chlorobenzo[d]thiazol-2-yl)-4-((3-methylpiperidin-1-yl)sulfonyl)benzohydrazide chemical structure, C20H21ClN4O3S2, CAS 851979-30-1
N'-(4-Chlorobenzo[d]thiazol-2-yl)-4-((3-methylpiperidin-1-yl)sulfonyl)benzohydrazide
CAS 851979-30-1C20H21ClN4O3S2
N'-(6-Methylbenzo[d]thiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzohydrazide chemical structure, C21H24N4O3S2, CAS 851979-65-2
N'-(6-Methylbenzo[d]thiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzohydrazide
CAS 851979-65-2C21H24N4O3S2
N'-(5,7-Dimethylbenzo[d]thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzohydrazide chemical structure, C21H24N4O3S2, CAS 851987-51-4
N'-(5,7-Dimethylbenzo[d]thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzohydrazide
CAS 851987-51-4C21H24N4O3S2
N'-(4,6-Difluorobenzo[d]thiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzohydrazide chemical structure, C20H20F2N4O3S2, CAS 851988-42-6
N'-(4,6-Difluorobenzo[d]thiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzohydrazide
CAS 851988-42-6C20H20F2N4O3S2
N'-(4-Methylbenzo[d]thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzohydrazide chemical structure, C20H22N4O3S2, CAS 851977-89-4
N'-(4-Methylbenzo[d]thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzohydrazide
CAS 851977-89-4C20H22N4O3S2
N'-(4-Methylbenzo[d]thiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzohydrazide chemical structure, C21H24N4O3S2, CAS 851978-05-7
N'-(4-Methylbenzo[d]thiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzohydrazide
CAS 851978-05-7C21H24N4O3S2
N'-(4-Methylbenzo[d]thiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzohydrazide chemical structure, C21H24N4O3S2, CAS 851978-07-9
N'-(4-Methylbenzo[d]thiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzohydrazide
CAS 851978-07-9C21H24N4O3S2
4-((2-Ethylpiperidin-1-yl)sulfonyl)-N'-(4-methylbenzo[d]thiazol-2-yl)benzohydrazide chemical structure, C22H26N4O3S2, CAS 851978-15-9
4-((2-Ethylpiperidin-1-yl)sulfonyl)-N'-(4-methylbenzo[d]thiazol-2-yl)benzohydrazide
CAS 851978-15-9C22H26N4O3S2
N'-(4-Methoxybenzo[d]thiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzohydrazide chemical structure, C21H24N4O4S2, CAS 851978-42-2
N'-(4-Methoxybenzo[d]thiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzohydrazide
CAS 851978-42-2C21H24N4O4S2
N'-(4-Methoxybenzo[d]thiazol-2-yl)-4-((3-methylpiperidin-1-yl)sulfonyl)benzohydrazide chemical structure, C21H24N4O4S2, CAS 851978-43-3
N'-(4-Methoxybenzo[d]thiazol-2-yl)-4-((3-methylpiperidin-1-yl)sulfonyl)benzohydrazide
CAS 851978-43-3C21H24N4O4S2
N'-(4-Methoxybenzo[d]thiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzohydrazide chemical structure, C21H24N4O4S2, CAS 851978-44-4
N'-(4-Methoxybenzo[d]thiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzohydrazide
CAS 851978-44-4C21H24N4O4S2
4-((2-Ethylpiperidin-1-yl)sulfonyl)-N'-(4-methoxybenzo[d]thiazol-2-yl)benzohydrazide chemical structure, C22H26N4O4S2, CAS 851978-51-3
4-((2-Ethylpiperidin-1-yl)sulfonyl)-N'-(4-methoxybenzo[d]thiazol-2-yl)benzohydrazide
CAS 851978-51-3C22H26N4O4S2
N'-(4-Ethoxybenzo[d]thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzohydrazide chemical structure, C21H24N4O4S2, CAS 851978-62-6
N'-(4-Ethoxybenzo[d]thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzohydrazide
CAS 851978-62-6C21H24N4O4S2
N'-(4-Fluorobenzo[d]thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzohydrazide chemical structure, C19H19FN4O3S2, CAS 851978-76-2
N'-(4-Fluorobenzo[d]thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzohydrazide
CAS 851978-76-2C19H19FN4O3S2
4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-N'-(4-fluorobenzo[d]thiazol-2-yl)benzohydrazide chemical structure, C21H23FN4O3S2, CAS 851978-86-4
4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-N'-(4-fluorobenzo[d]thiazol-2-yl)benzohydrazide
CAS 851978-86-4C21H23FN4O3S2