Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

1-((Pyrrolidine-1-carbonyl)methyl)piperazine scaffold

14 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 14
Chemicals: 14
With full pages: 5

Scaffold SMILES

O=C(CN1CCNCC1)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 1-((Pyrrolidine-1-carbonyl)methyl)piperazine page

Murcko scaffold O=C(CN1CCNCC1)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

1-((Pyrrolidine-1-carbonyl)methyl)piperazine chemical structure, C10H19N3O, CAS 39890-45-4

1-((Pyrrolidine-1-carbonyl)methyl)piperazine

CAS 39890-45-4C₁₀H₁₉N₃O

2-Chloro-1-{4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]piperazin-1-yl}ethan-1-one chemical structure, C12H20ClN3O2, CAS 885524-13-0

2-Chloro-1-{4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]piperazin-1-yl}ethan-1-one

CAS 885524-13-0C₁₂H₂₀ClN₃O₂

4-[2-Oxo-2-(pyrrolidin-1-yl)ethyl]piperazine-1-carbonyl chloride chemical structure, C11H18ClN3O2, CAS 136539-46-3

4-[2-Oxo-2-(pyrrolidin-1-yl)ethyl]piperazine-1-carbonyl chloride

CAS 136539-46-3C₁₁H₁₈ClN₃O₂

2-Chloro-1-{4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]piperazin-1-yl}ethan-1-one hydrochloride chemical structure, C12H21Cl2N3O2, CAS 1052539-77-1

2-Chloro-1-{4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]piperazin-1-yl}ethan-1-one hydrochloride

CAS 1052539-77-1C₁₂H₂₁Cl₂N₃O₂

2-(Piperazin-1-yl)-1-(pyrrolidin-1-yl)propan-1-one chemical structure, C11H21N3O, CAS 89574-40-3

2-(Piperazin-1-yl)-1-(pyrrolidin-1-yl)propan-1-one

CAS 89574-40-3C₁₁H₂₁N₃O

1-(1-Pyrrolidinylcarbonylmethyl)piperazine hydrochloride chemical structure, C10H20ClN3O, CAS 1198283-51-0

1-(1-Pyrrolidinylcarbonylmethyl)piperazine hydrochloride

CAS 1198283-51-0C₁₀H₂₀ClN₃O

4-(1,1-Dimethyl-2-oxo-2-pyrrolidin-1-yl-ethyl)-piperazine-1-carboxylic acid tert-butyl ester chemical structure, C17H31N3O3, CAS 885698-77-1

4-(1,1-Dimethyl-2-oxo-2-pyrrolidin-1-yl-ethyl)-piperazine-1-carboxylic acid tert-butyl ester

CAS 885698-77-1C₁₇H₃₁N₃O₃

2-(2,2-Dimethylpiperazin-1-yl)-1-pyrrolidin-1-ylethanone chemical structure, C12H23N3O, CAS 1263387-98-9

2-(2,2-Dimethylpiperazin-1-yl)-1-pyrrolidin-1-ylethanone

CAS 1263387-98-9C₁₂H₂₃N₃O

2-(Piperazin-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one dihydrochloride chemical structure, C10H21Cl2N3O, CAS 1182708-84-4

2-(Piperazin-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one dihydrochloride

CAS 1182708-84-4C₁₀H₂₁Cl₂N₃O

2-(4-Aminopiperazin-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one chemical structure, C10H20N4O, CAS 39856-02-5

2-(4-Aminopiperazin-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one

CAS 39856-02-5C₁₀H₂₀N₄O

N-(2-Cyano-3-methylbutan-2-yl)-2-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]acetamide chemical structure, C18H31N5O2, CAS 1623367-18-9

N-(2-Cyano-3-methylbutan-2-yl)-2-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]acetamide

CAS 1623367-18-9C₁₈H₃₁N₅O₂

2-{4-[2-Oxo-2-(pyrrolidin-1-yl)ethyl]piperazin-1-yl}-N-(propan-2-yl)propanamide chemical structure, C16H30N4O2, CAS 2741900-88-7

2-{4-[2-Oxo-2-(pyrrolidin-1-yl)ethyl]piperazin-1-yl}-N-(propan-2-yl)propanamide

CAS 2741900-88-7C₁₆H₃₀N₄O₂

4-[2-Oxo-2-(pyrrolidin-1-yl)ethyl]piperazine-1-sulfonyl chloride chemical structure, C10H18ClN3O3S, CAS 2870660-75-4

4-[2-Oxo-2-(pyrrolidin-1-yl)ethyl]piperazine-1-sulfonyl chloride

CAS 2870660-75-4C₁₀H₁₈ClN₃O₃S

2-(4-Nitrosopiperazin-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one chemical structure, C10H18N4O2, CAS 2870652-88-1

2-(4-Nitrosopiperazin-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one

CAS 2870652-88-1C₁₀H₁₈N₄O₂