CompoundList
Sign in
Murcko scaffold

8-(4-Oxo-4-phenylbutyl)-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one scaffold

29 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
29
With full pages
3
Scaffold SMILES

O=C(CCCN1CCC2(CC1)C(=O)NCN2c1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 8-(4-Oxo-4-phenylbutyl)-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one page
Murcko scaffold O=C(CCCN1CCC2(CC1)C(=O)NCN2c1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 29 of 29 chemicals

Spiperone chemical structure, C23H26FN3O2, CAS 749-02-0
Spiperone
CAS 749-02-0C23H26FN3O2
8-(4-Oxo-4-phenylbutyl)-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one chemical structure, C23H27N3O2, CAS 1054-89-3
8-(4-Oxo-4-phenylbutyl)-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one
CAS 1054-89-3C23H27N3O2
N-Methylspiroperidol chemical structure, C24H28FN3O2, CAS 87539-19-3
N-Methylspiroperidol
CAS 87539-19-3C24H28FN3O2
1,3,8-Triazaspiro(4.5)decan-4-one, 3-acetyl-8-(3-(p-fluorobenzoyl)propyl)-1-phenyl-, hydrochloride chemical structure, C25H29ClFN3O3, CAS 1060-33-9
1,3,8-Triazaspiro(4.5)decan-4-one, 3-acetyl-8-(3-(p-fluorobenzoyl)propyl)-1-phenyl-, hydrochloride
CAS 1060-33-9C25H29ClFN3O3
2'-Iodospiperone chemical structure, C23H25FIN3O2, CAS 103445-60-9
2'-Iodospiperone
CAS 103445-60-9C23H25FIN3O2
4-Azido-N-methylspiperone chemical structure, C24H27FN6O2, CAS 104820-55-5
4-Azido-N-methylspiperone
CAS 104820-55-5C24H27FN6O2
3-N-(2-Fluoroethyl)spiperone chemical structure, C25H29F2N3O2, CAS 106114-42-5
3-N-(2-Fluoroethyl)spiperone
CAS 106114-42-5C25H29F2N3O2
N-(3-Fluoropropyl)spiroperidol chemical structure, C26H31F2N3O2, CAS 106114-44-7
N-(3-Fluoropropyl)spiroperidol
CAS 106114-44-7C26H31F2N3O2
Iodoethylspiperone chemical structure, C25H29FIN3O2, CAS 130482-21-2
Iodoethylspiperone
CAS 130482-21-2C25H29FIN3O2
4-Iodospiperone chemical structure, C23H25FIN3O2, CAS 85562-22-7
4-Iodospiperone
CAS 85562-22-7C23H25FIN3O2
4-Bromospiperone chemical structure, C23H25BrFN3O2, CAS 76139-30-5
4-Bromospiperone
CAS 76139-30-5C23H25BrFN3O2
Fluspiperone chemical structure, C23H25F2N3O2, CAS 54965-22-9
Fluspiperone
CAS 54965-22-9C23H25F2N3O2
4-Aminospiroperidol chemical structure, C23H27FN4O2, CAS 114442-96-5
4-Aminospiroperidol
CAS 114442-96-5C23H27FN4O2
3-(2-Aminoethyl)-8-(3-(4-fluorobenzoyl)propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one chemical structure, C25H34Cl3FN4O2, CAS 125094-03-3
3-(2-Aminoethyl)-8-(3-(4-fluorobenzoyl)propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one
CAS 125094-03-3C25H34Cl3FN4O2
1,3,8-Triazaspiro(4.5)decan-4-one, 8-(3-(p-fluorobenzoyl)propyl)-3-methyl-1-phenyl-, hydrochloride chemical structure, C24H29ClFN3O2, CAS 3725-68-6
1,3,8-Triazaspiro(4.5)decan-4-one, 8-(3-(p-fluorobenzoyl)propyl)-3-methyl-1-phenyl-, hydrochloride
CAS 3725-68-6C24H29ClFN3O2
1,3,8-Triazaspiro(4.5)decan-4-one, 8-(3-(p-(dimethylamino)benzoyl)propyl)-1-phenyl- chemical structure, C25H32N4O2, CAS 102395-57-3
1,3,8-Triazaspiro(4.5)decan-4-one, 8-(3-(p-(dimethylamino)benzoyl)propyl)-1-phenyl-
CAS 102395-57-3C25H32N4O2
1,3,8-Triazaspiro(4.5)decan-4-one, 8-(3-(p-fluorobenzoyl)propyl)-3-isopropyl-1-phenyl-, hydrochloride chemical structure, C26H33ClFN3O2, CAS 102504-74-5
1,3,8-Triazaspiro(4.5)decan-4-one, 8-(3-(p-fluorobenzoyl)propyl)-3-isopropyl-1-phenyl-, hydrochloride
CAS 102504-74-5C26H33ClFN3O2
1,3,8-Triazaspiro(4.5)decan-4-one, 8-(4-(4-fluorophenyl)-4-oxobutyl)-3-(1-methylpropyl)-1-phenyl-, monohydrochloride chemical structure, C27H35ClFN3O2, CAS 102395-53-9
1,3,8-Triazaspiro(4.5)decan-4-one, 8-(4-(4-fluorophenyl)-4-oxobutyl)-3-(1-methylpropyl)-1-phenyl-, monohydrochloride
CAS 102395-53-9C27H35ClFN3O2
1,3,8-Triazaspiro(4,5)decane-3-carboxamide, 8-(3-(p-fluorobenzoyl)propyl)-N-methyl-4-oxo-1-phenyl-, hydrochloride chemical structure, C25H30ClFN4O3, CAS 54286-36-1
1,3,8-Triazaspiro(4,5)decane-3-carboxamide, 8-(3-(p-fluorobenzoyl)propyl)-N-methyl-4-oxo-1-phenyl-, hydrochloride
CAS 54286-36-1C25H30ClFN4O3
Fesp F-18 chemical structure, C25H29F2N3O2, CAS 107340-59-0
Fesp F-18
CAS 107340-59-0C25H29F2N3O2
Mespiperone (11C) chemical structure, C24H28FN3O2, CAS 94153-50-1
Mespiperone (11C)
CAS 94153-50-1C24H28FN3O2
N-(Iodoallyl)spiperone chemical structure, C26H29FIN3O2, CAS 124654-22-4
N-(Iodoallyl)spiperone
CAS 124654-22-4C26H29FIN3O2
Spiperone hydrochloride chemical structure, C23H27ClFN3O2, CAS 2022-29-9
Spiperone hydrochloride
CAS 2022-29-9C23H27ClFN3O2
Mespiperone F-18 chemical structure, C24H28FN3O2, CAS 96203-19-9
Mespiperone F-18
CAS 96203-19-9C24H28FN3O2