CompoundList
Sign in
Murcko scaffold

2-(2,5-Dioxo-1-phenylpyrrolidin-3-yl)sulfanyl-N-naphthalen-2-ylacetamide scaffold

15 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
15
With full pages
2
Scaffold SMILES

O=C(CSC1CC(=O)N(c2ccccc2)C1=O)Nc1ccc2ccccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(2,5-Dioxo-1-phenylpyrrolidin-3-yl)sulfanyl-N-naphthalen-2-ylacetamide page
Murcko scaffold O=C(CSC1CC(=O)N(c2ccccc2)C1=O)Nc1ccc2ccccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

2-[1-(4-Ethoxyphenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl-N-naphthalen-2-ylacetamide chemical structure, C24H22N2O4S, CAS 332126-03-1
2-[1-(4-Ethoxyphenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl-N-naphthalen-2-ylacetamide
CAS 332126-03-1C24H22N2O4S
2-[1-(3-Chlorophenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl-N-naphthalen-2-ylacetamide chemical structure, C22H17ClN2O3S, CAS 332125-92-5
2-[1-(3-Chlorophenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl-N-naphthalen-2-ylacetamide
CAS 332125-92-5C22H17ClN2O3S
4-[3-[2-(Naphthalen-2-ylamino)-2-oxoethyl]sulfanyl-2,5-dioxopyrrolidin-1-yl]benzoic acid chemical structure, C23H18N2O5S, CAS 296771-28-3
4-[3-[2-(Naphthalen-2-ylamino)-2-oxoethyl]sulfanyl-2,5-dioxopyrrolidin-1-yl]benzoic acid
CAS 296771-28-3C23H18N2O5S
2-{[1-(3,4-Dichlorophenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl}-N-(naphthalen-2-yl)acetamide chemical structure, C22H16Cl2N2O3S, CAS 331759-59-2
2-{[1-(3,4-Dichlorophenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl}-N-(naphthalen-2-yl)acetamide
CAS 331759-59-2C22H16Cl2N2O3S
2-{[1-(3-Methoxyphenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl}-N-(naphthalen-2-yl)acetamide chemical structure, C23H20N2O4S, CAS 314038-48-7
2-{[1-(3-Methoxyphenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl}-N-(naphthalen-2-yl)acetamide
CAS 314038-48-7C23H20N2O4S
2-[1-(3,5-Dichlorophenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl-N-naphthalen-2-ylacetamide chemical structure, C22H16Cl2N2O3S, CAS 331759-44-5
2-[1-(3,5-Dichlorophenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl-N-naphthalen-2-ylacetamide
CAS 331759-44-5C22H16Cl2N2O3S
Methyl 4-[3-[2-(naphthalen-2-ylamino)-2-oxoethyl]sulfanyl-2,5-dioxopyrrolidin-1-yl]benzoate chemical structure, C24H20N2O5S, CAS 330865-42-4
Methyl 4-[3-[2-(naphthalen-2-ylamino)-2-oxoethyl]sulfanyl-2,5-dioxopyrrolidin-1-yl]benzoate
CAS 330865-42-4C24H20N2O5S
2-[1-(3-Ethoxyphenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl-N-naphthalen-2-ylacetamide chemical structure, C24H22N2O4S, CAS 332052-97-8
2-[1-(3-Ethoxyphenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl-N-naphthalen-2-ylacetamide
CAS 332052-97-8C24H22N2O4S
2-{[1-(2-Fluorophenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl}-N-(naphthalen-2-yl)acetamide chemical structure, C22H17FN2O3S, CAS 301325-77-9
2-{[1-(2-Fluorophenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl}-N-(naphthalen-2-yl)acetamide
CAS 301325-77-9C22H17FN2O3S
2-[1-(4-Fluorophenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl-N-naphthalen-2-ylacetamide chemical structure, C22H17FN2O3S, CAS 332125-96-9
2-[1-(4-Fluorophenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl-N-naphthalen-2-ylacetamide
CAS 332125-96-9C22H17FN2O3S
2-[1-(3-Bromophenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl-N-naphthalen-2-ylacetamide chemical structure, C22H17BrN2O3S, CAS 327986-72-1
2-[1-(3-Bromophenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl-N-naphthalen-2-ylacetamide
CAS 327986-72-1C22H17BrN2O3S
Ethyl 4-(3-{[2-(naphthalen-2-ylamino)-2-oxoethyl]sulfanyl}-2,5-dioxopyrrolidin-1-yl)benzoate chemical structure, C25H22N2O5S, CAS 330864-74-9
Ethyl 4-(3-{[2-(naphthalen-2-ylamino)-2-oxoethyl]sulfanyl}-2,5-dioxopyrrolidin-1-yl)benzoate
CAS 330864-74-9C25H22N2O5S
2-(2,5-Dioxo-1-phenylpyrrolidin-3-yl)sulfanyl-N-naphthalen-2-ylacetamide chemical structure, C22H18N2O3S, CAS 519045-12-6
2-(2,5-Dioxo-1-phenylpyrrolidin-3-yl)sulfanyl-N-naphthalen-2-ylacetamide
CAS 519045-12-6C22H18N2O3S
2-{[1-(4-Chlorophenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl}-N-(naphthalen-2-yl)acetamide chemical structure, C22H17ClN2O3S, CAS 384351-79-5
2-{[1-(4-Chlorophenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl}-N-(naphthalen-2-yl)acetamide
CAS 384351-79-5C22H17ClN2O3S
2-[[1-[4-Chloro-3-(trifluoromethyl)phenyl]-2,5-dioxo-3-pyrrolidinyl]thio]-N-2-naphthalenylacetamide chemical structure, C23H16ClF3N2O3S, CAS 381673-11-6
2-[[1-[4-Chloro-3-(trifluoromethyl)phenyl]-2,5-dioxo-3-pyrrolidinyl]thio]-N-2-naphthalenylacetamide
CAS 381673-11-6C23H16ClF3N2O3S