Murcko scaffold
Ring system with 4 rings and 32 atoms
16 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 32
- Chemicals
- 16
- With full pages
- 4
Scaffold SMILES
O=C(CSc1nnc(-c2ccccc2)n1-c1ccccc1)NN=CC=Cc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 16 of 16 chemicals
2-((5-(4-Chlorophenyl)-4-(4-methylphenyl)-4H-1,2,4-triazol-3-yl)sulfanyl)-N'-((E,2E)-3-(2-nitrophenyl)-2-propenylidene)acetohydrazide
CAS 307975-53-7C26H21ClN6O3S
![2-[[5-(4-Methoxyphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]-N-[(Z)-[(E)-3-phenylprop-2-enylidene]amino]acetamide chemical structure, C26H23N5O2S, CAS 314289-22-0](/s/ZYVJJWFTZJFKKK-UWRPBMCQSA-N.svg)
2-[[5-(4-Methoxyphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]-N-[(Z)-[(E)-3-phenylprop-2-enylidene]amino]acetamide
CAS 314289-22-0C26H23N5O2S
![N-[(Z)-[(Z)-2-Chloro-3-phenylprop-2-enylidene]amino]-2-[[5-(4-methoxyphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C26H22ClN5O2S, CAS 314288-96-5](/s/HWBLGPRZXUGPQN-CJBNVOHASA-N.svg)
N-[(Z)-[(Z)-2-Chloro-3-phenylprop-2-enylidene]amino]-2-[[5-(4-methoxyphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 314288-96-5C26H22ClN5O2S
![2-[[5-(4-tert-Butylphenyl)-4-(4-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(E)-[(E)-3-phenylprop-2-enylidene]amino]acetamide chemical structure, C30H31N5OS, CAS 488858-21-5](/s/XGONPDWJPQJZDW-SSTMMHSMSA-N.svg)
2-[[5-(4-tert-Butylphenyl)-4-(4-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(E)-[(E)-3-phenylprop-2-enylidene]amino]acetamide
CAS 488858-21-5C30H31N5OS
![2-[[5-(4-tert-Butylphenyl)-4-(4-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(E)-[(Z)-2-chloro-3-phenylprop-2-enylidene]amino]acetamide chemical structure, C30H30ClN5OS, CAS 488803-56-1](/s/NFVRYZAUBLQTEO-SLTHAPGXSA-N.svg)
2-[[5-(4-tert-Butylphenyl)-4-(4-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(E)-[(Z)-2-chloro-3-phenylprop-2-enylidene]amino]acetamide
CAS 488803-56-1C30H30ClN5OS
![N-[(Z)-[(Z)-2-Chloro-3-phenylprop-2-enylidene]amino]-2-[[5-(4-methylphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C26H22ClN5OS, CAS 306752-94-3](/s/UKZPOMTVTLEILD-ZDZWWMTKSA-N.svg)
N-[(Z)-[(Z)-2-Chloro-3-phenylprop-2-enylidene]amino]-2-[[5-(4-methylphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 306752-94-3C26H22ClN5OS
![2-{[4,5-Bis(4-chlorophenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N'-[(E,2E)-3-(2-methoxyphenyl)-2-propenylidene]acetohydrazide chemical structure, C26H21Cl2N5O2S, CAS 489440-95-1](/s/SWDYEUJHWDQWHE-UABMNINZSA-N.svg)
2-{[4,5-Bis(4-chlorophenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N'-[(E,2E)-3-(2-methoxyphenyl)-2-propenylidene]acetohydrazide
CAS 489440-95-1C26H21Cl2N5O2S
![2-[[5-(4-Methylphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]-N-[(Z)-[(E)-3-phenylprop-2-enylidene]amino]acetamide chemical structure, C26H23N5OS, CAS 314287-95-1](/s/LSPKTXQJAAEYRL-UWRPBMCQSA-N.svg)
2-[[5-(4-Methylphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]-N-[(Z)-[(E)-3-phenylprop-2-enylidene]amino]acetamide
CAS 314287-95-1C26H23N5OS
![N'-[(1E,2Z)-2-Bromo-3-phenylprop-2-en-1-ylidene]-2-{[5-(4-methylphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetohydrazide chemical structure, C26H22BrN5OS, CAS 314287-98-4](/s/JOAOVYPNIFOUOA-ZDZWWMTKSA-N.svg)
N'-[(1E,2Z)-2-Bromo-3-phenylprop-2-en-1-ylidene]-2-{[5-(4-methylphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetohydrazide
CAS 314287-98-4C26H22BrN5OS
![N'-[(1E,2E)-3-(2-Methoxyphenyl)prop-2-en-1-ylidene]-2-{[5-(4-methylphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetohydrazide chemical structure, C27H25N5O2S, CAS 314288-01-2](/s/OPZJFZATTYBYAA-BHFAATOSSA-N.svg)
N'-[(1E,2E)-3-(2-Methoxyphenyl)prop-2-en-1-ylidene]-2-{[5-(4-methylphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetohydrazide
CAS 314288-01-2C27H25N5O2S
![2-{[4,5-Bis(4-chlorophenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N'-[(1Z,2Z)-2-chloro-3-phenylprop-2-en-1-ylidene]acetohydrazide chemical structure, C25H18Cl3N5OS, CAS 498544-26-6](/s/FZQREWNAWBVLGA-RHSWHVRTSA-N.svg)
2-{[4,5-Bis(4-chlorophenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N'-[(1Z,2Z)-2-chloro-3-phenylprop-2-en-1-ylidene]acetohydrazide
CAS 498544-26-6C25H18Cl3N5OS
![2-[[5-(4-Methoxyphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]-N-[(Z)-[(E)-2-methyl-3-phenylprop-2-enylidene]amino]acetamide chemical structure, C27H25N5O2S, CAS 314289-09-3](/s/ZMWOASKYCLQGEY-NINPINDZSA-N.svg)
2-[[5-(4-Methoxyphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]-N-[(Z)-[(E)-2-methyl-3-phenylprop-2-enylidene]amino]acetamide
CAS 314289-09-3C27H25N5O2S
![N'-[(E,2Z)-2-Bromo-3-phenyl-2-propenylidene]-2-{[5-(4-chlorophenyl)-4-(4-methylphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetohydrazide chemical structure, C26H21BrClN5OS, CAS 307975-54-8](/s/JVJDZSNLSLCVPH-ZGBFTUMVSA-N.svg)
N'-[(E,2Z)-2-Bromo-3-phenyl-2-propenylidene]-2-{[5-(4-chlorophenyl)-4-(4-methylphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetohydrazide
CAS 307975-54-8C26H21BrClN5OS
N'-((E,2Z)-2-Bromo-3-phenyl-2-propenylidene)-2-((5-(4-tert-butylphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)sulfanyl)acetohydrazide
CAS 307975-58-2C29H28BrN5OS
![2-{[5-(4-Chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N'-[(1E,2E)-2-methyl-3-phenylprop-2-en-1-ylidene]acetohydrazide chemical structure, C26H22ClN5OS, CAS 306757-85-7](/s/YUARXJSCWJBTDZ-SILQRRHJSA-N.svg)
2-{[5-(4-Chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N'-[(1E,2E)-2-methyl-3-phenylprop-2-en-1-ylidene]acetohydrazide
CAS 306757-85-7C26H22ClN5OS
2-((5-(4-tert-Butylphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)sulfanyl)-N'-((E,2E)-3-(2-nitrophenyl)-2-propenylidene)acetohydrazide
CAS 307975-57-1C29H28N6O3S