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Murcko scaffold

Ring system with 2 rings and 15 atoms

10 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
10
With full pages
8
Scaffold SMILES

O=C1NC=CC(C=Cc2ccccc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC=CC(C=Cc2ccccc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

5-Pyrimidinecarboxylicacid,1,2,3,4-tetrahydro-6-methyl-2-oxo-4-(2-phenylethenyl)-,2-propenylester(9CI) chemical structure, C17H18N2O3, CAS 434312-15-9
5-Pyrimidinecarboxylicacid,1,2,3,4-tetrahydro-6-methyl-2-oxo-4-(2-phenylethenyl)-,2-propenylester(9CI)
CAS 434312-15-9C17H18N2O3
Ethyl 6-methyl-2-oxo-4-[(E)-1-phenylprop-1-en-2-yl]-3,4-dihydro-1H-pyrimidine-5-carboxylate chemical structure, C17H20N2O3, CAS 1164454-29-8
Ethyl 6-methyl-2-oxo-4-[(E)-1-phenylprop-1-en-2-yl]-3,4-dihydro-1H-pyrimidine-5-carboxylate
CAS 1164454-29-8C17H20N2O3
Ethyl 6-methyl-2-oxo-4-(2-phenylvinyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate chemical structure, C16H18N2O3, CAS 123629-39-0
Ethyl 6-methyl-2-oxo-4-(2-phenylvinyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
CAS 123629-39-0C16H18N2O3
Methyl 4-[(E)-2-(2-methoxyphenyl)ethenyl]-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate chemical structure, C16H18N2O4, CAS 433255-37-9
Methyl 4-[(E)-2-(2-methoxyphenyl)ethenyl]-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
CAS 433255-37-9C16H18N2O4
2-Oxo-4-styryl-6-methyl-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid methyl ester chemical structure, C15H16N2O3, CAS 1164483-47-9
2-Oxo-4-styryl-6-methyl-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid methyl ester
CAS 1164483-47-9C15H16N2O3
Isopropyl 4-[2-(2-methoxyphenyl)vinyl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C18H22N2O4, CAS 488812-61-9
Isopropyl 4-[2-(2-methoxyphenyl)vinyl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
CAS 488812-61-9C18H22N2O4
2-Methoxyethyl 6-methyl-2-oxo-4-(2-phenylvinyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate chemical structure, C17H20N2O4, CAS 1164483-32-2
2-Methoxyethyl 6-methyl-2-oxo-4-(2-phenylvinyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
CAS 1164483-32-2C17H20N2O4
Ethyl 2-hydroxy-6-[(E)-2-(2-methoxyphenyl)ethenyl]-4-methyl-1,6-dihydropyrimidine-5-carboxylate chemical structure, C17H20N2O4, CAS 433325-44-1
Ethyl 2-hydroxy-6-[(E)-2-(2-methoxyphenyl)ethenyl]-4-methyl-1,6-dihydropyrimidine-5-carboxylate
CAS 433325-44-1C17H20N2O4
2-Methoxyethyl 4-[(E)-2-(2-methoxyphenyl)ethenyl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C18H22N2O5, CAS 690647-14-4
2-Methoxyethyl 4-[(E)-2-(2-methoxyphenyl)ethenyl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
CAS 690647-14-4C18H22N2O5
5-Pyrimidinecarboxylicacid,1,2,3,4-tetrahydro-6-methyl-2-oxo-4-(2-phenylethenyl)-,1-methylethylester(9CI) chemical structure, C17H20N2O3, CAS 498568-38-0
5-Pyrimidinecarboxylicacid,1,2,3,4-tetrahydro-6-methyl-2-oxo-4-(2-phenylethenyl)-,1-methylethylester(9CI)
CAS 498568-38-0C17H20N2O3