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Murcko scaffold

(2-Phenylquinolin-4-yl)(4-(pyridin-2-yl)piperazin-1-yl)methanone scaffold

8 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
30
Chemicals
8
With full pages
1
Scaffold SMILES

O=C(c1cc(-c2ccccc2)nc2ccccc12)N1CCN(c2ccccn2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the (2-Phenylquinolin-4-yl)(4-(pyridin-2-yl)piperazin-1-yl)methanone page
Murcko scaffold O=C(c1cc(-c2ccccc2)nc2ccccc12)N1CCN(c2ccccn2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

[6-Bromo-2-(4-ethoxyphenyl)quinolin-4-yl]-(4-pyridin-2-ylpiperazin-1-yl)methanone chemical structure, C27H25BrN4O2, CAS 445234-46-8
[6-Bromo-2-(4-ethoxyphenyl)quinolin-4-yl]-(4-pyridin-2-ylpiperazin-1-yl)methanone
CAS 445234-46-8C27H25BrN4O2
(2-Phenylquinolin-4-yl)(4-(pyridin-2-yl)piperazin-1-yl)methanone chemical structure, C25H22N4O, CAS 690669-04-6
(2-Phenylquinolin-4-yl)(4-(pyridin-2-yl)piperazin-1-yl)methanone
CAS 690669-04-6C25H22N4O
[2-(2-Methoxyphenyl)quinolin-4-yl]-(4-pyridin-2-ylpiperazin-1-yl)methanone chemical structure, C26H24N4O2, CAS 823831-61-4
[2-(2-Methoxyphenyl)quinolin-4-yl]-(4-pyridin-2-ylpiperazin-1-yl)methanone
CAS 823831-61-4C26H24N4O2
[2-(3-Bromophenyl)-8-methylquinolin-4-yl]-(4-pyridin-2-ylpiperazin-1-yl)methanone chemical structure, C26H23BrN4O, CAS 777868-95-8
[2-(3-Bromophenyl)-8-methylquinolin-4-yl]-(4-pyridin-2-ylpiperazin-1-yl)methanone
CAS 777868-95-8C26H23BrN4O
[2-(2-Chlorophenyl)-4-quinolyl][4-(2-pyridyl)piperazino]methanone chemical structure, C25H21ClN4O, CAS 492429-31-9
[2-(2-Chlorophenyl)-4-quinolyl][4-(2-pyridyl)piperazino]methanone
CAS 492429-31-9C25H21ClN4O
[2-(4-Fluorophenyl)-4-quinolyl][4-(2-pyridyl)piperazino]methanone chemical structure, C25H21FN4O, CAS 1062119-64-5
[2-(4-Fluorophenyl)-4-quinolyl][4-(2-pyridyl)piperazino]methanone
CAS 1062119-64-5C25H21FN4O
[2-(3,4-Dimethoxyphenyl)-4-quinolyl][4-(2-pyridyl)piperazino]methanone chemical structure, C27H26N4O3, CAS 1144488-63-0
[2-(3,4-Dimethoxyphenyl)-4-quinolyl][4-(2-pyridyl)piperazino]methanone
CAS 1144488-63-0C27H26N4O3
[2-(3-Methoxyphenyl)-4-quinolyl][4-(2-pyridyl)piperazino]methanone chemical structure, C26H24N4O2, CAS 1144457-55-5
[2-(3-Methoxyphenyl)-4-quinolyl][4-(2-pyridyl)piperazino]methanone
CAS 1144457-55-5C26H24N4O2