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Murcko scaffold

1,3-Dioxoisoindolin-2-yl cyclobutanecarboxylate scaffold

81 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 18
Chemicals: 81
With full pages: 5

Scaffold SMILES

O=C(ON1C(=O)c2ccccc2C1=O)C1CCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 1,3-Dioxoisoindolin-2-yl cyclobutanecarboxylate page

Murcko scaffold O=C(ON1C(=O)c2ccccc2C1=O)C1CCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 81 chemicals

3-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl) 1-methyl 1-methylcyclobutane-1,3-dicarboxylate chemical structure, C16H15NO6, CAS 2402830-94-6

3-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl) 1-methyl 1-methylcyclobutane-1,3-dicarboxylate

CAS 2402830-94-6C₁₆H₁₅NO₆

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-{[(tert-butoxy)carbonyl]amino}cyclobutane-1-carboxylate chemical structure, C18H20N2O6, CAS 2135459-00-4

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-{[(tert-butoxy)carbonyl]amino}cyclobutane-1-carboxylate

CAS 2135459-00-4C₁₈H₂₀N₂O₆

1,3-Dioxoisoindolin-2-yl 1-methylcyclobutane-1-carboxylate chemical structure, C14H13NO4, CAS 2248326-94-3

1,3-Dioxoisoindolin-2-yl 1-methylcyclobutane-1-carboxylate

CAS 2248326-94-3C₁₄H₁₃NO₄

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-{[(tert-butoxy)carbonyl](methyl)amino}-3,3-difluorocyclobutane-1-carboxylate chemical structure, C19H20F2N2O6, CAS 2248318-80-9

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-{[(tert-butoxy)carbonyl](methyl)amino}-3,3-difluorocyclobutane-1-carboxylate

CAS 2248318-80-9C₁₉H₂₀F₂N₂O₆

1,3-Dioxoisoindolin-2-yl cyclobutanecarboxylate chemical structure, C13H11NO4, CAS 1872262-64-0

1,3-Dioxoisoindolin-2-yl cyclobutanecarboxylate

CAS 1872262-64-0C₁₃H₁₁NO₄

1,3-Dioxoisoindolin-2-yl cis-3-((tert-butoxycarbonyl)amino)cyclobutane-1-carboxylate chemical structure, C18H20N2O6, CAS 2248201-94-5

1,3-Dioxoisoindolin-2-yl cis-3-((tert-butoxycarbonyl)amino)cyclobutane-1-carboxylate

CAS 2248201-94-5C₁₈H₂₀N₂O₆

1-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl) 1-ethyl cyclobutane-1,1-dicarboxylate chemical structure, C16H15NO6, CAS 2248275-31-0

1-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl) 1-ethyl cyclobutane-1,1-dicarboxylate

CAS 2248275-31-0C₁₆H₁₅NO₆

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 3,3-difluorocyclobutane-1-carboxylate chemical structure, C13H9F2NO4, CAS 2248328-40-5

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 3,3-difluorocyclobutane-1-carboxylate

CAS 2248328-40-5C₁₃H₉F₂NO₄

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 3-{[(tert-butoxy)carbonyl](methyl)amino}cyclobutane-1-carboxylate chemical structure, C19H22N2O6, CAS 2248365-71-9

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 3-{[(tert-butoxy)carbonyl](methyl)amino}cyclobutane-1-carboxylate

CAS 2248365-71-9C₁₉H₂₂N₂O₆

1,3-Dioxoisoindolin-2-yl 3,3-dimethylcyclobutane-1-carboxylate chemical structure, C15H15NO4, CAS 2248270-81-5

1,3-Dioxoisoindolin-2-yl 3,3-dimethylcyclobutane-1-carboxylate

CAS 2248270-81-5C₁₅H₁₅NO₄

1,3-Dioxoisoindolin-2-yl 3-methylcyclobutane-1-carboxylate chemical structure, C14H13NO4, CAS 2248320-42-3

1,3-Dioxoisoindolin-2-yl 3-methylcyclobutane-1-carboxylate

CAS 2248320-42-3C₁₄H₁₃NO₄

1,3-Dioxoisoindolin-2-yl 3-fluorocyclobutane-1-carboxylate chemical structure, C13H10FNO4, CAS 2248414-83-5

1,3-Dioxoisoindolin-2-yl 3-fluorocyclobutane-1-carboxylate

CAS 2248414-83-5C₁₃H₁₀FNO₄

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-cyanocyclobutane-1-carboxylate chemical structure, C14H10N2O4, CAS 2248275-10-5

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-cyanocyclobutane-1-carboxylate

CAS 2248275-10-5C₁₄H₁₀N₂O₄

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 2,2-difluorocyclobutane-1-carboxylate chemical structure, C13H9F2NO4, CAS 2248345-74-4

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 2,2-difluorocyclobutane-1-carboxylate

CAS 2248345-74-4C₁₃H₉F₂NO₄

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 2,2-dimethylcyclobutane-1-carboxylate chemical structure, C15H15NO4, CAS 2248363-32-6

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 2,2-dimethylcyclobutane-1-carboxylate

CAS 2248363-32-6C₁₅H₁₅NO₄

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-(methylsulfanyl)cyclobutane-1-carboxylate chemical structure, C14H13NO4S, CAS 2248276-51-7

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-(methylsulfanyl)cyclobutane-1-carboxylate

CAS 2248276-51-7C₁₄H₁₃NO₄S

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-(2-ethoxyethyl)cyclobutane-1-carboxylate chemical structure, C17H19NO5, CAS 2248396-32-7

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-(2-ethoxyethyl)cyclobutane-1-carboxylate

CAS 2248396-32-7C₁₇H₁₉NO₅

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 3-(propan-2-yl)cyclobutane-1-carboxylate chemical structure, C16H17NO4, CAS 2248283-28-3

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 3-(propan-2-yl)cyclobutane-1-carboxylate

CAS 2248283-28-3C₁₆H₁₇NO₄

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-propylcyclobutane-1-carboxylate chemical structure, C16H17NO4, CAS 2248316-59-6

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-propylcyclobutane-1-carboxylate

CAS 2248316-59-6C₁₆H₁₇NO₄

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 3-ethoxycyclobutane-1-carboxylate chemical structure, C15H15NO5, CAS 2248314-57-8

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 3-ethoxycyclobutane-1-carboxylate

CAS 2248314-57-8C₁₅H₁₅NO₅

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 3-ethyl-3-methylcyclobutane-1-carboxylate chemical structure, C16H17NO4, CAS 2248301-11-1

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 3-ethyl-3-methylcyclobutane-1-carboxylate

CAS 2248301-11-1C₁₆H₁₇NO₄

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-cyano-3-methylcyclobutane-1-carboxylate chemical structure, C15H12N2O4, CAS 2248369-96-0

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-cyano-3-methylcyclobutane-1-carboxylate

CAS 2248369-96-0C₁₅H₁₂N₂O₄

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 3-fluoro-3-methylcyclobutane-1-carboxylate chemical structure, C14H12FNO4, CAS 2248407-21-6

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 3-fluoro-3-methylcyclobutane-1-carboxylate

CAS 2248407-21-6C₁₄H₁₂FNO₄

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-methoxycyclobutane-1-carboxylate chemical structure, C14H13NO5, CAS 2248279-19-6

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-methoxycyclobutane-1-carboxylate

CAS 2248279-19-6C₁₄H₁₃NO₅