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Murcko scaffold

3-Phenylglutarimide scaffold

69 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
69
With full pages
11
Scaffold SMILES

O=C1CC(c2ccccc2)CC(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenylglutarimide page
Murcko scaffold O=C1CC(c2ccccc2)CC(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 69 chemicals

4-Methyl-4-phenylpiperidine-2,6-dione chemical structure, C12H13NO2, CAS 14149-32-7
4-Methyl-4-phenylpiperidine-2,6-dione
CAS 14149-32-7C12H13NO2
Glutarimide, 3-ethyl-3-phenyl- chemical structure, C13H15NO2, CAS 2900-50-7
Glutarimide, 3-ethyl-3-phenyl-
CAS 2900-50-7C13H15NO2
3-Phenylglutarimide chemical structure, C11H11NO2, CAS 14149-31-6
3-Phenylglutarimide
CAS 14149-31-6C11H11NO2
N-(4-(4-Ethyl-2,6-dioxo-4-piperidyl)phenyl)acetamide chemical structure, C15H18N2O3, CAS 91828-60-3
N-(4-(4-Ethyl-2,6-dioxo-4-piperidyl)phenyl)acetamide
CAS 91828-60-3C15H18N2O3
Glutarimide, N-allyl-3-phenyl- chemical structure, C14H15NO2, CAS 10259-37-7
Glutarimide, N-allyl-3-phenyl-
CAS 10259-37-7C14H15NO2
2,6-Dioxo-4-phenyl-piperidine-3-carbonitrile chemical structure, C12H10N2O2, CAS 54459-77-7
2,6-Dioxo-4-phenyl-piperidine-3-carbonitrile
CAS 54459-77-7C12H10N2O2
4-Methyl-2,6-dioxo-4-phenylpiperidine-3,5-dicarbonitrile chemical structure, C14H11N3O2, CAS 6936-95-4
4-Methyl-2,6-dioxo-4-phenylpiperidine-3,5-dicarbonitrile
CAS 6936-95-4C14H11N3O2
1-(2-Chloroethyl)-4-(4-methoxyphenyl)piperidine-2,6-dione chemical structure, C14H16ClNO3, CAS 75436-69-0
1-(2-Chloroethyl)-4-(4-methoxyphenyl)piperidine-2,6-dione
CAS 75436-69-0C14H16ClNO3
[4-(4-Methoxyphenyl)-2,6-dioxopiperidin-1-yl]acetic acid chemical structure, C14H15NO5, CAS 76734-06-0
[4-(4-Methoxyphenyl)-2,6-dioxopiperidin-1-yl]acetic acid
CAS 76734-06-0C14H15NO5
4-(2-Methoxyphenyl)-2,6-dioxo-3,5-piperidinedicarbonitrile chemical structure, C14H11N3O3, CAS 73843-58-0
4-(2-Methoxyphenyl)-2,6-dioxo-3,5-piperidinedicarbonitrile
CAS 73843-58-0C14H11N3O3
4-(4-Methoxyphenyl)piperidine-2,6-dione chemical structure, C12H13NO3, CAS 33868-98-3
4-(4-Methoxyphenyl)piperidine-2,6-dione
CAS 33868-98-3C12H13NO3
4-(4-Chlorophenyl)piperidine-2,6-dione chemical structure, C11H10ClNO2, CAS 84803-46-3
4-(4-Chlorophenyl)piperidine-2,6-dione
CAS 84803-46-3C11H10ClNO2
Glutarimide, N-methyl-3-phenyl- chemical structure, C12H13NO2, CAS 54946-26-8
Glutarimide, N-methyl-3-phenyl-
CAS 54946-26-8C12H13NO2
Glutarimide, N-ethyl-3-phenyl- chemical structure, C13H15NO2, CAS 54946-27-9
Glutarimide, N-ethyl-3-phenyl-
CAS 54946-27-9C13H15NO2
(2,6-Dioxo-4-phenyl-piperidin-1-yl)-acetic acid chemical structure, C13H13NO4, CAS 876711-03-4
(2,6-Dioxo-4-phenyl-piperidin-1-yl)-acetic acid
CAS 876711-03-4C13H13NO4
4-(4-Chlorophenyl)-4-methyl-2,6-dioxopiperidine-3,5-dicarbonitrile chemical structure, C14H10ClN3O2, CAS 92161-82-5
4-(4-Chlorophenyl)-4-methyl-2,6-dioxopiperidine-3,5-dicarbonitrile
CAS 92161-82-5C14H10ClN3O2
(±)-Trans-3-ethoxycarbonyl-4(4'-fluorophenyl)piperidin-2,6-dione chemical structure, C14H14FNO4, CAS 109887-51-6
(±)-Trans-3-ethoxycarbonyl-4(4'-fluorophenyl)piperidin-2,6-dione
CAS 109887-51-6C14H14FNO4
4-(4-Fluorophenyl)piperidine-2,6-dione chemical structure, C11H10FNO2, CAS 163631-01-4
4-(4-Fluorophenyl)piperidine-2,6-dione
CAS 163631-01-4C11H10FNO2
4-(3,4-Dimethoxyphenyl)piperidine-2,6-dione chemical structure, C13H15NO4, CAS 42434-75-3
4-(3,4-Dimethoxyphenyl)piperidine-2,6-dione
CAS 42434-75-3C13H15NO4
1,4-Dimethyl-2,6-dioxo-4-phenylpiperidine-3,5-dicarbonitrile chemical structure, C15H13N3O2, CAS 43030-33-7
1,4-Dimethyl-2,6-dioxo-4-phenylpiperidine-3,5-dicarbonitrile
CAS 43030-33-7C15H13N3O2
4-(4-Bromophenyl)piperidine-2,6-dione chemical structure, C11H10BrNO2, CAS 1137-60-6
4-(4-Bromophenyl)piperidine-2,6-dione
CAS 1137-60-6C11H10BrNO2
4-(3-Chlorophenyl)piperidine-2,6-dione chemical structure, C11H10ClNO2, CAS 113675-65-3
4-(3-Chlorophenyl)piperidine-2,6-dione
CAS 113675-65-3C11H10ClNO2
Ethyl 4-(4-fluorophenyl)-1-methyl-2,6-dioxopiperidine-3-carboxylate chemical structure, C15H16FNO4, CAS 202534-94-9
Ethyl 4-(4-fluorophenyl)-1-methyl-2,6-dioxopiperidine-3-carboxylate
CAS 202534-94-9C15H16FNO4
Methyl 4-(4-fluorophenyl)-1-methyl-2,6-dioxopiperidine-3-carboxylate chemical structure, C14H14FNO4, CAS 188302-27-4
Methyl 4-(4-fluorophenyl)-1-methyl-2,6-dioxopiperidine-3-carboxylate
CAS 188302-27-4C14H14FNO4