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Murcko scaffold

Ring system with 4 rings and 22 atoms

39 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
39
With full pages
3
Scaffold SMILES

O=C(Nc1nc2c(s1)CCc1ccccc1-2)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1nc2c(s1)CCc1ccccc1-2)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

N-(4,5-Dihydronaphtho[1,2-d][1,3]thiazol-2-yl)-3-fluorobenzamide chemical structure, C18H13FN2OS, CAS 300541-66-6
N-(4,5-Dihydronaphtho[1,2-d][1,3]thiazol-2-yl)-3-fluorobenzamide
CAS 300541-66-6C18H13FN2OS
N-(4,5-Dihydronaphtho[1,2-d]thiazol-2-yl)-3-methoxybenzamide chemical structure, C19H16N2O2S, CAS 361160-35-2
N-(4,5-Dihydronaphtho[1,2-d]thiazol-2-yl)-3-methoxybenzamide
CAS 361160-35-2C19H16N2O2S
N-(4,5-Dihydronaphtho[1,2-d][1,3]thiazol-2-yl)-4-methoxybenzamide chemical structure, C19H16N2O2S, CAS 361160-47-6
N-(4,5-Dihydronaphtho[1,2-d][1,3]thiazol-2-yl)-4-methoxybenzamide
CAS 361160-47-6C19H16N2O2S
2-Chloro-N-(4,5-dihydrobenzo[e][1,3]benzothiazol-2-yl)benzamide chemical structure, C18H13ClN2OS, CAS 692269-32-2
2-Chloro-N-(4,5-dihydrobenzo[e][1,3]benzothiazol-2-yl)benzamide
CAS 692269-32-2C18H13ClN2OS
N-(4,5-Dihydronaphtho[1,2-d]thiazol-2-yl)-2,6-difluorobenzamide chemical structure, C18H12F2N2OS, CAS 330189-06-5
N-(4,5-Dihydronaphtho[1,2-d]thiazol-2-yl)-2,6-difluorobenzamide
CAS 330189-06-5C18H12F2N2OS
N-(4,5-Dihydronaphtho[1,2-d]thiazol-2-yl)-4-methylbenzamide chemical structure, C19H16N2OS, CAS 313404-69-2
N-(4,5-Dihydronaphtho[1,2-d]thiazol-2-yl)-4-methylbenzamide
CAS 313404-69-2C19H16N2OS
N-(4,5-Dihydro-naphtho[1,2-d]thiazol-2-yl)-3,4,5-trimethoxy-benzamide chemical structure, C21H20N2O4S, CAS 361160-45-4
N-(4,5-Dihydro-naphtho[1,2-d]thiazol-2-yl)-3,4,5-trimethoxy-benzamide
CAS 361160-45-4C21H20N2O4S
N-(4,5-Dihydronaphtho[1,2-d]thiazol-2-yl)-2,6-dimethoxybenzamide chemical structure, C20H18N2O3S, CAS 441289-74-3
N-(4,5-Dihydronaphtho[1,2-d]thiazol-2-yl)-2,6-dimethoxybenzamide
CAS 441289-74-3C20H18N2O3S
N-(4,5-Dihydronaphtho[1,2-d][1,3]thiazol-2-yl)-4-nitrobenzamide chemical structure, C18H13N3O3S, CAS 300541-77-9
N-(4,5-Dihydronaphtho[1,2-d][1,3]thiazol-2-yl)-4-nitrobenzamide
CAS 300541-77-9C18H13N3O3S
4-Bromo-N-{4H,5H-naphtho[1,2-d][1,3]thiazol-2-yl}benzamide chemical structure, C18H13BrN2OS, CAS 377057-36-8
4-Bromo-N-{4H,5H-naphtho[1,2-d][1,3]thiazol-2-yl}benzamide
CAS 377057-36-8C18H13BrN2OS
N-(4,5-Dihydrobenzo[e][1,3]benzothiazol-2-yl)-4-(dimethylsulfamoyl)benzamide chemical structure, C20H19N3O3S2, CAS 313404-68-1
N-(4,5-Dihydrobenzo[e][1,3]benzothiazol-2-yl)-4-(dimethylsulfamoyl)benzamide
CAS 313404-68-1C20H19N3O3S2
N-{4H,5H-naphtho[1,2-d][1,3]thiazol-2-yl}-3-nitrobenzamide chemical structure, C18H13N3O3S, CAS 313404-70-5
N-{4H,5H-naphtho[1,2-d][1,3]thiazol-2-yl}-3-nitrobenzamide
CAS 313404-70-5C18H13N3O3S
N-(4,5-Dihydronaphtho[1,2-d]thiazol-2-yl)-3,5-dimethoxybenzamide chemical structure, C20H18N2O3S, CAS 313405-09-3
N-(4,5-Dihydronaphtho[1,2-d]thiazol-2-yl)-3,5-dimethoxybenzamide
CAS 313405-09-3C20H18N2O3S
N-(4,5-Dihydrobenzo[e][1,3]benzothiazol-2-yl)-2-methoxybenzamide chemical structure, C19H16N2O2S, CAS 361160-30-7
N-(4,5-Dihydrobenzo[e][1,3]benzothiazol-2-yl)-2-methoxybenzamide
CAS 361160-30-7C19H16N2O2S
N-(4,5-Dihydronaphtho[1,2-d]thiazol-2-yl)-4-(N,N-dipropylsulfamoyl)benzamide chemical structure, C24H27N3O3S2, CAS 325988-24-7
N-(4,5-Dihydronaphtho[1,2-d]thiazol-2-yl)-4-(N,N-dipropylsulfamoyl)benzamide
CAS 325988-24-7C24H27N3O3S2
4-Cyano-N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)benzamide chemical structure, C19H13N3OS, CAS 325988-52-1
4-Cyano-N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)benzamide
CAS 325988-52-1C19H13N3OS
2,5-Dichloro-N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)benzamide chemical structure, C18H12Cl2N2OS, CAS 392246-45-6
2,5-Dichloro-N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)benzamide
CAS 392246-45-6C18H12Cl2N2OS
4-Chloro-N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)benzamide chemical structure, C18H13ClN2OS, CAS 353487-78-2
4-Chloro-N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)benzamide
CAS 353487-78-2C18H13ClN2OS
3-Chloro-N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)benzamide chemical structure, C18H13ClN2OS, CAS 378214-69-8
3-Chloro-N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)benzamide
CAS 378214-69-8C18H13ClN2OS
4-Butoxy-N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)benzamide chemical structure, C22H22N2O2S, CAS 476275-92-0
4-Butoxy-N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)benzamide
CAS 476275-92-0C22H22N2O2S
N-(4,5-Dihydronaphtho[1,2-d]thiazol-2-yl)-2-nitrobenzamide chemical structure, C18H13N3O3S, CAS 378200-05-6
N-(4,5-Dihydronaphtho[1,2-d]thiazol-2-yl)-2-nitrobenzamide
CAS 378200-05-6C18H13N3O3S
4-(N,N-Bis(2-cyanoethyl)sulfamoyl)-N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)benzamide chemical structure, C24H21N5O3S2, CAS 476275-05-5
4-(N,N-Bis(2-cyanoethyl)sulfamoyl)-N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)benzamide
CAS 476275-05-5C24H21N5O3S2
3-Bromo-N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)benzamide chemical structure, C18H13BrN2OS, CAS 376625-32-0
3-Bromo-N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)benzamide
CAS 376625-32-0C18H13BrN2OS
4-(N,N-Diallylsulfamoyl)-N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)benzamide chemical structure, C24H23N3O3S2, CAS 441289-93-6
4-(N,N-Diallylsulfamoyl)-N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)benzamide
CAS 441289-93-6C24H23N3O3S2