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Murcko scaffold

Ring system with 5 rings and 24 atoms

14 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
24
Chemicals
14
With full pages
5
Scaffold SMILES

c1ccc(C2CC(N3CCCC3)Oc3cc4c(cc32)OCO4)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C2CC(N3CCCC3)Oc3cc4c(cc32)OCO4)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

1-(7,8-Dihydro-8-(4-methoxyphenyl)-6-methyl-6H-1,3-dioxolo(4,5-g)(1)benzopyran-6-yl)pyrrolidine chemical structure, C22H25NO4, CAS 116385-22-9
1-(7,8-Dihydro-8-(4-methoxyphenyl)-6-methyl-6H-1,3-dioxolo(4,5-g)(1)benzopyran-6-yl)pyrrolidine
CAS 116385-22-9C22H25NO4
1-(7,8-Dihydro-8-(4-methoxyphenyl)-7-methyl-6H-1,3-dioxolo(4,5-g)(1)benzopyran-6-yl)pyrrolidine chemical structure, C22H25NO4, CAS 116385-29-6
1-(7,8-Dihydro-8-(4-methoxyphenyl)-7-methyl-6H-1,3-dioxolo(4,5-g)(1)benzopyran-6-yl)pyrrolidine
CAS 116385-29-6C22H25NO4
1-(8-(2,4-Dimethoxyphenyl)-7,8-dihydro-7-methyl-6H-1,3-dioxolo(4,5-g)(1)benzopyran-6-yl)pyrrolidine chemical structure, C23H27NO5, CAS 116385-34-3
1-(8-(2,4-Dimethoxyphenyl)-7,8-dihydro-7-methyl-6H-1,3-dioxolo(4,5-g)(1)benzopyran-6-yl)pyrrolidine
CAS 116385-34-3C23H27NO5
2-(7,8-Dihydro-6-methyl-6-(1-pyrrolidinyl)-6H-1,3-dioxolo(4,5-g)(1)benzopyran-8-yl)-6-methoxyphenol chemical structure, C22H25NO5, CAS 116408-96-9
2-(7,8-Dihydro-6-methyl-6-(1-pyrrolidinyl)-6H-1,3-dioxolo(4,5-g)(1)benzopyran-8-yl)-6-methoxyphenol
CAS 116408-96-9C22H25NO5
2-(7,8-Dihydro-7-methyl-6-(1-pyrrolidinyl)-6H-1,3-dioxolo(4,5-g)(1)benzopyran-8-yl)-6-methoxyphenol chemical structure, C22H25NO5, CAS 116408-98-1
2-(7,8-Dihydro-7-methyl-6-(1-pyrrolidinyl)-6H-1,3-dioxolo(4,5-g)(1)benzopyran-8-yl)-6-methoxyphenol
CAS 116408-98-1C22H25NO5
Ethyl 6-methyl-6-pyrrolidin-1-yl-8-(3,4,5-trimethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]chromene-7-carboxylate chemical structure, C27H33NO8, CAS 116409-00-8
Ethyl 6-methyl-6-pyrrolidin-1-yl-8-(3,4,5-trimethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]chromene-7-carboxylate
CAS 116409-00-8C27H33NO8
1-(7,8-Dihydro-7-methyl-8-(3,4,5-trimethoxyphenyl)-6H-1,3-dioxolo(4,5-g)(1)benzopyran-6-yl)pyrrolidine chemical structure, C24H29NO6, CAS 116409-04-2
1-(7,8-Dihydro-7-methyl-8-(3,4,5-trimethoxyphenyl)-6H-1,3-dioxolo(4,5-g)(1)benzopyran-6-yl)pyrrolidine
CAS 116409-04-2C24H29NO6
1-(7,8-Dihydro-6,7-dimethyl-8-(3,4,5-trimethoxyphenyl)-6H-1,3-dioxolo(4,5-g)(1)benzopyran-6-yl)pyrrolidine chemical structure, C25H31NO6, CAS 116409-20-2
1-(7,8-Dihydro-6,7-dimethyl-8-(3,4,5-trimethoxyphenyl)-6H-1,3-dioxolo(4,5-g)(1)benzopyran-6-yl)pyrrolidine
CAS 116409-20-2C25H31NO6
1-[6-Methyl-8-(3,4,5-trimethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]chromen-6-yl]pyrrolidine chemical structure, C24H29NO6, CAS 116409-25-7
1-[6-Methyl-8-(3,4,5-trimethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]chromen-6-yl]pyrrolidine
CAS 116409-25-7C24H29NO6
1-(7,8-Dihydro-6-methyl-8-(2,4,6-trimethoxyphenyl)-6H-1,3-dioxolo(4,5-g)(1)benzopyran-6-yl)pyrrolidine chemical structure, C24H29NO6, CAS 117211-97-9
1-(7,8-Dihydro-6-methyl-8-(2,4,6-trimethoxyphenyl)-6H-1,3-dioxolo(4,5-g)(1)benzopyran-6-yl)pyrrolidine
CAS 117211-97-9C24H29NO6
1-(8-(2,4-Dimethoxyphenyl)-7,8-dihydro-6-methyl-6H-1,3-dioxolo(4,5-g)(1)benzopyran-6-yl)pyrrolidine chemical structure, C23H27NO5, CAS 117212-00-7
1-(8-(2,4-Dimethoxyphenyl)-7,8-dihydro-6-methyl-6H-1,3-dioxolo(4,5-g)(1)benzopyran-6-yl)pyrrolidine
CAS 117212-00-7C23H27NO5
1-[8-(2-Ethoxyphenyl)-6,7-dimethyl-7,8-dihydro-6H-[1,3]dioxolo[4,5-g]chromen-6-yl]pyrrolidine chemical structure, C24H29NO4, CAS 1005116-71-1
1-[8-(2-Ethoxyphenyl)-6,7-dimethyl-7,8-dihydro-6H-[1,3]dioxolo[4,5-g]chromen-6-yl]pyrrolidine
CAS 1005116-71-1C24H29NO4
1-[8-(3,4-Dichlorophenyl)-6,7-dimethyl-7,8-dihydro-6H-[1,3]dioxolo[4,5-g]chromen-6-yl]pyrrolidine chemical structure, C22H23Cl2NO3, CAS 1005106-24-0
1-[8-(3,4-Dichlorophenyl)-6,7-dimethyl-7,8-dihydro-6H-[1,3]dioxolo[4,5-g]chromen-6-yl]pyrrolidine
CAS 1005106-24-0C22H23Cl2NO3
1-[8-(4-Bromophenyl)-6,7-dimethyl-7,8-dihydro-6H-[1,3]dioxolo[4,5-g]chromen-6-yl]pyrrolidine chemical structure, C22H24BrNO3, CAS 1005150-37-7
1-[8-(4-Bromophenyl)-6,7-dimethyl-7,8-dihydro-6H-[1,3]dioxolo[4,5-g]chromen-6-yl]pyrrolidine
CAS 1005150-37-7C22H24BrNO3