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Murcko scaffold

2-Cyclohexyl-2,3-dihydro-1H-isoindol-1-one scaffold

28 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
28
With full pages
2
Scaffold SMILES

O=C1c2ccccc2CN1C1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Cyclohexyl-2,3-dihydro-1H-isoindol-1-one page
Murcko scaffold O=C1c2ccccc2CN1C1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

Clorexolone chemical structure, C14H17ClN2O3S, CAS 2127-01-7
Clorexolone
CAS 2127-01-7C14H17ClN2O3S
2-Cyclohexyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid chemical structure, C15H17NO3, CAS 626205-17-2
2-Cyclohexyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid
CAS 626205-17-2C15H17NO3
Butanoic acid,4-[[4-chloro-2,3-dihydro-2-(2-methylcyclohexyl)-1-oxo-1H-isoindol-5-yl]oxy]- chemical structure, C19H24ClNO4, CAS 153144-19-5
Butanoic acid,4-[[4-chloro-2,3-dihydro-2-(2-methylcyclohexyl)-1-oxo-1H-isoindol-5-yl]oxy]-
CAS 153144-19-5C19H24ClNO4
Acetic acid,2-[(4-chloro-2-cyclohexyl-2,3-dihydro-1-oxo-1H-isoindol-5-yl)oxy]- chemical structure, C16H18ClNO4, CAS 153144-23-1
Acetic acid,2-[(4-chloro-2-cyclohexyl-2,3-dihydro-1-oxo-1H-isoindol-5-yl)oxy]-
CAS 153144-23-1C16H18ClNO4
2-Cyclohexyl-2,3-dihydro-1H-isoindol-1-one chemical structure, C14H17NO, CAS 3823-13-0
2-Cyclohexyl-2,3-dihydro-1H-isoindol-1-one
CAS 3823-13-0C14H17NO
2-Cyclohexyl-4-nitro-1-isoindolinone chemical structure, C14H16N2O3, CAS 900015-12-5
2-Cyclohexyl-4-nitro-1-isoindolinone
CAS 900015-12-5C14H16N2O3
4-Amino-2-cyclohexyl-1-isoindolinone chemical structure, C14H18N2O, CAS 882747-51-5
4-Amino-2-cyclohexyl-1-isoindolinone
CAS 882747-51-5C14H18N2O
5-Amino-2-cyclohexyl-2,3-dihydro-1H-isoindol-1-one chemical structure, C14H18N2O, CAS 217493-23-7
5-Amino-2-cyclohexyl-2,3-dihydro-1H-isoindol-1-one
CAS 217493-23-7C14H18N2O
tert-Butyl (1R*,4R*)-4-(1-oxoisoindolin-2-yl)cyclohexylcarbamate chemical structure, C19H26N2O3, CAS 412357-35-8
tert-Butyl (1R*,4R*)-4-(1-oxoisoindolin-2-yl)cyclohexylcarbamate
CAS 412357-35-8C19H26N2O3
2-(trans-4-Aminocyclohexyl)isoindolin-1-one hydrochloride chemical structure, C14H19ClN2O, CAS 412356-10-6
2-(trans-4-Aminocyclohexyl)isoindolin-1-one hydrochloride
CAS 412356-10-6C14H19ClN2O
5-Bromo-2-cyclohexylisoindolin-1-one chemical structure, C14H16BrNO, CAS 735351-81-2
5-Bromo-2-cyclohexylisoindolin-1-one
CAS 735351-81-2C14H16BrNO
5-Bromo-2-(trans-4-hydroxycyclohexyl)isoindolin-1-one chemical structure, C14H16BrNO2, CAS 918331-66-5
5-Bromo-2-(trans-4-hydroxycyclohexyl)isoindolin-1-one
CAS 918331-66-5C14H16BrNO2
1H-Isoindol-1-one,4-chloro-2,3-dihydro-5-methoxy-2-(2-methylcyclohexyl)- chemical structure, C16H20ClNO2, CAS 153144-48-0
1H-Isoindol-1-one,4-chloro-2,3-dihydro-5-methoxy-2-(2-methylcyclohexyl)-
CAS 153144-48-0C16H20ClNO2
1H-Isoindol-1-one,4-chloro-2-cyclohexyl-2,3-dihydro-5-(3-hydroxypropoxy)- chemical structure, C17H22ClNO3, CAS 153144-33-3
1H-Isoindol-1-one,4-chloro-2-cyclohexyl-2,3-dihydro-5-(3-hydroxypropoxy)-
CAS 153144-33-3C17H22ClNO3
1H-Isoindol-1-one,4-chloro-2-cyclohexyl-2,3-dihydro-5-hydroxy- chemical structure, C14H16ClNO2, CAS 153144-30-0
1H-Isoindol-1-one,4-chloro-2-cyclohexyl-2,3-dihydro-5-hydroxy-
CAS 153144-30-0C14H16ClNO2
1H-Isoindol-1-one,4-chloro-2-cyclohexyl-2,3-dihydro-5-methoxy- chemical structure, C15H18ClNO2, CAS 153144-45-7
1H-Isoindol-1-one,4-chloro-2-cyclohexyl-2,3-dihydro-5-methoxy-
CAS 153144-45-7C15H18ClNO2
Acetic acid,2-[(4-chloro-2-cyclohexyl-2,3-dihydro-1-oxo-1H-isoindol-5-yl)oxy]-,ethyl ester chemical structure, C18H22ClNO4, CAS 153144-21-9
Acetic acid,2-[(4-chloro-2-cyclohexyl-2,3-dihydro-1-oxo-1H-isoindol-5-yl)oxy]-,ethyl ester
CAS 153144-21-9C18H22ClNO4
Butanoic acid,4-[(4-chloro-2-cyclohexyl-2,3-dihydro-1-oxo-1H-isoindol-5-yl)oxy]-,ethyl ester chemical structure, C20H26ClNO4, CAS 153144-13-9
Butanoic acid,4-[(4-chloro-2-cyclohexyl-2,3-dihydro-1-oxo-1H-isoindol-5-yl)oxy]-,ethyl ester
CAS 153144-13-9C20H26ClNO4
2-(trans-4-Aminocyclohexyl)-7-fluoroisoindolin-1-one hydrochloride chemical structure, C14H18ClFN2O, CAS 1707367-78-9
2-(trans-4-Aminocyclohexyl)-7-fluoroisoindolin-1-one hydrochloride
CAS 1707367-78-9C14H18ClFN2O
tert-Butyl (1R*,4R*)-4-(7-fluoro-1-oxoisoindolin-2-yl)cyclohexylcarbamate chemical structure, C19H25FN2O3, CAS 1713160-81-6
tert-Butyl (1R*,4R*)-4-(7-fluoro-1-oxoisoindolin-2-yl)cyclohexylcarbamate
CAS 1713160-81-6C19H25FN2O3
2-(trans-4-Aminocyclohexyl)-5-fluoroisoindolin-1-one hydrochloride chemical structure, C14H18ClFN2O, CAS 1707358-57-3
2-(trans-4-Aminocyclohexyl)-5-fluoroisoindolin-1-one hydrochloride
CAS 1707358-57-3C14H18ClFN2O
tert-Butyl (1R*,4R*)-4-(5-fluoro-1-oxoisoindolin-2-yl)cyclohexylcarbamate chemical structure, C19H25FN2O3, CAS 1707367-80-3
tert-Butyl (1R*,4R*)-4-(5-fluoro-1-oxoisoindolin-2-yl)cyclohexylcarbamate
CAS 1707367-80-3C19H25FN2O3
2-(trans-4-Aminocyclohexyl)-4-fluoroisoindolin-1-one hydrochloride chemical structure, C14H18ClFN2O, CAS 1707367-84-7
2-(trans-4-Aminocyclohexyl)-4-fluoroisoindolin-1-one hydrochloride
CAS 1707367-84-7C14H18ClFN2O
tert-Butyl (1R*,4R*)-4-(4-fluoro-1-oxoisoindolin-2-yl)cyclohexylcarbamate chemical structure, C19H25FN2O3, CAS 1707358-61-9
tert-Butyl (1R*,4R*)-4-(4-fluoro-1-oxoisoindolin-2-yl)cyclohexylcarbamate
CAS 1707358-61-9C19H25FN2O3