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Murcko scaffold

Ring system with 2 rings and 15 atoms

16 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
16
With full pages
7
Scaffold SMILES

O=c1ccccn1N=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccccn1N=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

1-(Benzylideneimino)-2,4-dimethyl-5-cyano-6-pyridone chemical structure, C15H13N3O
1-(Benzylideneimino)-2,4-dimethyl-5-cyano-6-pyridone
C15H13N3O
1-[[(2-Hydroxyphenyl)methylene]amino]-4,6-dimethyl-2(1H)-pyridinone chemical structure, C14H14N2O2, CAS 315671-10-4
1-[[(2-Hydroxyphenyl)methylene]amino]-4,6-dimethyl-2(1H)-pyridinone
CAS 315671-10-4C14H14N2O2
1-[(E)-(2-Chloro-5-nitrophenyl)methylideneamino]-4,6-dimethylpyridin-2-one chemical structure, C14H12ClN3O3, CAS 356769-29-4
1-[(E)-(2-Chloro-5-nitrophenyl)methylideneamino]-4,6-dimethylpyridin-2-one
CAS 356769-29-4C14H12ClN3O3
1-[(E)-[4-(Diethylamino)phenyl]methylideneamino]-4,6-dimethylpyridin-2-one chemical structure, C18H23N3O, CAS 327066-11-5
1-[(E)-[4-(Diethylamino)phenyl]methylideneamino]-4,6-dimethylpyridin-2-one
CAS 327066-11-5C18H23N3O
1-(Benzalamino)-2-keto-4,6-dimethyl-nicotinonitrile chemical structure, C15H13N3O, CAS 89814-99-3
1-(Benzalamino)-2-keto-4,6-dimethyl-nicotinonitrile
CAS 89814-99-3C15H13N3O
4,6-Dimethyl-1-[(E)-(3-nitrophenyl)methylideneamino]pyridin-2-one chemical structure, C14H13N3O3, CAS 315671-11-5
4,6-Dimethyl-1-[(E)-(3-nitrophenyl)methylideneamino]pyridin-2-one
CAS 315671-11-5C14H13N3O3
1-[(4-Methoxybenzylidene)amino]-4,6-dimethyl-2(1H)-pyridinone chemical structure, C15H16N2O2, CAS 315671-14-8
1-[(4-Methoxybenzylidene)amino]-4,6-dimethyl-2(1H)-pyridinone
CAS 315671-14-8C15H16N2O2
1-[(4-Methoxybenzylidene)amino]-4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinecarbonitrile chemical structure, C16H15N3O2, CAS 183473-54-3
1-[(4-Methoxybenzylidene)amino]-4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinecarbonitrile
CAS 183473-54-3C16H15N3O2
1-[(E)-(3-Hydroxyphenyl)methylideneamino]-4,6-dimethyl-2-oxopyridine-3-carbonitrile chemical structure, C15H13N3O2, CAS 31558-16-4
1-[(E)-(3-Hydroxyphenyl)methylideneamino]-4,6-dimethyl-2-oxopyridine-3-carbonitrile
CAS 31558-16-4C15H13N3O2
(E)-4-(((3-Cyano-4,6-dimethyl-2-oxopyridin-1(2H)-yl)imino)methyl)-2-methoxyphenyl acetate chemical structure, C18H17N3O4, CAS 31558-13-1
(E)-4-(((3-Cyano-4,6-dimethyl-2-oxopyridin-1(2H)-yl)imino)methyl)-2-methoxyphenyl acetate
CAS 31558-13-1C18H17N3O4
4,6-Dimethyl-1-[(E)-(4-methylsulfanylphenyl)methylideneamino]pyridin-2-one chemical structure, C15H16N2OS, CAS 327066-01-3
4,6-Dimethyl-1-[(E)-(4-methylsulfanylphenyl)methylideneamino]pyridin-2-one
CAS 327066-01-3C15H16N2OS
4,6-Dimethyl-1-[(E)-(4-nitrophenyl)methylideneamino]pyridin-2-one chemical structure, C14H13N3O3, CAS 100868-00-6
4,6-Dimethyl-1-[(E)-(4-nitrophenyl)methylideneamino]pyridin-2-one
CAS 100868-00-6C14H13N3O3
1-({(E)-[4-(Difluoromethoxy)phenyl]methylidene}amino)-4,6-dimethylpyridin-2(1H)-one chemical structure, C15H14F2N2O2, CAS 828278-33-7
1-({(E)-[4-(Difluoromethoxy)phenyl]methylidene}amino)-4,6-dimethylpyridin-2(1H)-one
CAS 828278-33-7C15H14F2N2O2
1-[(2-Hydroxy-5-nitrobenzylidene)amino]-4,6-dimethyl-2(1H)-pyridinone chemical structure, C14H13N3O4, CAS 356769-33-0
1-[(2-Hydroxy-5-nitrobenzylidene)amino]-4,6-dimethyl-2(1H)-pyridinone
CAS 356769-33-0C14H13N3O4
1-[[(E)-(3-Methoxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]amino]-4,6-dimethyl-2-oxopyridine-3-carbonitrile chemical structure, C16H15N3O3, CAS 31558-12-0
1-[[(E)-(3-Methoxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]amino]-4,6-dimethyl-2-oxopyridine-3-carbonitrile
CAS 31558-12-0C16H15N3O3
4,6-Dimethyl-2-oxo-1-[[(E)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]pyridine-3-carbonitrile chemical structure, C15H13N3O2, CAS 31558-18-6
4,6-Dimethyl-2-oxo-1-[[(E)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]pyridine-3-carbonitrile
CAS 31558-18-6C15H13N3O2