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Murcko scaffold

Acmc-1ccs8 scaffold

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
8
With full pages
3
Scaffold SMILES

c1ccc([SiH](c2ccccc2)[SiH](c2ccccc2)c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Acmc-1ccs8 page
Murcko scaffold c1ccc([SiH](c2ccccc2)[SiH](c2ccccc2)c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

1,2-Dimethyl-1,1,2,2-tetraphenyldisilane chemical structure, C26H26Si2, CAS 1172-76-5
1,2-Dimethyl-1,1,2,2-tetraphenyldisilane
CAS 1172-76-5C26H26Si2
1,1,2,2-Tetra(o-tolyl)-1,2-disilanediol chemical structure, C28H30O2Si2, CAS 18858-63-4
1,1,2,2-Tetra(o-tolyl)-1,2-disilanediol
CAS 18858-63-4C28H30O2Si2
Acmc-1ccs8 chemical structure, C24H22Si2, CAS 16343-18-3
Acmc-1ccs8
CAS 16343-18-3C24H22Si2
1,2-Dichloro-1,1,2,2-tetraphenyldisilane chemical structure, C24H20Cl2Si2, CAS 15288-62-7
1,2-Dichloro-1,1,2,2-tetraphenyldisilane
CAS 15288-62-7C24H20Cl2Si2
Tetrakis(2,4,6-trimethylphenyl)disilane-1,2-diol chemical structure, C36H46O2Si2, CAS 88589-60-0
Tetrakis(2,4,6-trimethylphenyl)disilane-1,2-diol
CAS 88589-60-0C36H46O2Si2
1,2-Di-tert-butyl-1,1,2,2-tetraphenyldisilane chemical structure, C32H38Si2, CAS 122131-73-1
1,2-Di-tert-butyl-1,1,2,2-tetraphenyldisilane
CAS 122131-73-1C32H38Si2
1,2-Dibromo-1,1,2,2-tetraphenyldisilane chemical structure, C24H20Br2Si2, CAS 18737-91-2
1,2-Dibromo-1,1,2,2-tetraphenyldisilane
CAS 18737-91-2C24H20Br2Si2
Lithium [diphenyl(trimethylsilyloxy)silyl]-diphenylsilanide chemical structure, C27H29LiOSi3, CAS 823207-35-8
Lithium [diphenyl(trimethylsilyloxy)silyl]-diphenylsilanide
CAS 823207-35-8C27H29LiOSi3