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Murcko scaffold

Ring system with 5 rings and 32 atoms

6 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
32
Chemicals
6
With full pages
1
Scaffold SMILES

O=C1N(Cc2ccc(-c3ccccc3S(=O)(=O)Nc3ccon3)cc2)C=NC12CCCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1N(Cc2ccc(-c3ccccc3S(=O)(=O)Nc3ccon3)cc2)C=NC12CCCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Sparsentan impurity 3 chemical structure, C30H34N4O5S, CAS 254737-96-7
Sparsentan impurity 3
CAS 254737-96-7C30H34N4O5S
Sparsentan chemical structure, C32H40N4O5S, CAS 254740-64-2
Sparsentan
CAS 254740-64-2C32H40N4O5S
4'-((2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl)-N-(4,5-dimethylisoxazol-3-yl)-2'-(ethoxymethyl)-N-(methoxymethyl)-[1,1'-biphenyl]-2-sulfonamide chemical structure, C34H44N4O6S, CAS 1026355-73-6
4'-((2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl)-N-(4,5-dimethylisoxazol-3-yl)-2'-(ethoxymethyl)-N-(methoxymethyl)-[1,1'-biphenyl]-2-sulfonamide
CAS 1026355-73-6C34H44N4O6S
4'-((2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-EN-3-yl)methyl)-N-(4,5-dimethylisoxazol-3-yl)-2'-methyl-[1,1'-biphenyl]-2-sulfonamide chemical structure, C30H36N4O4S, CAS 254741-40-7
4'-((2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-EN-3-yl)methyl)-N-(4,5-dimethylisoxazol-3-yl)-2'-methyl-[1,1'-biphenyl]-2-sulfonamide
CAS 254741-40-7C30H36N4O4S
Sparsentan-d5 chemical structure, C32H40N4O5S, CAS 1801597-09-0
Sparsentan-d5
CAS 1801597-09-0C32H40N4O5S
Sparsentan impurity 2 chemical structure, C32H38N4O6S, CAS 1399412-15-7
Sparsentan impurity 2
CAS 1399412-15-7C32H38N4O6S