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Murcko scaffold

N-[4-(4-Benzylpiperazin-1-yl)phenyl]pyridine-3-carboxamide scaffold

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
5
With full pages
2
Scaffold SMILES

O=C(Nc1ccc(N2CCN(Cc3ccccc3)CC2)cc1)c1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-[4-(4-Benzylpiperazin-1-yl)phenyl]pyridine-3-carboxamide page
Murcko scaffold O=C(Nc1ccc(N2CCN(Cc3ccccc3)CC2)cc1)c1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

N-[4-(4-Benzylpiperazin-1-yl)phenyl]-5-bromopyridine-3-carboxamide chemical structure, C23H23BrN4O, CAS 708240-30-6
N-[4-(4-Benzylpiperazin-1-yl)phenyl]-5-bromopyridine-3-carboxamide
CAS 708240-30-6C23H23BrN4O
N-[4-(4-Benzylpiperazin-1-yl)phenyl]pyridine-3-carboxamide chemical structure, C23H24N4O, CAS 573948-93-3
N-[4-(4-Benzylpiperazin-1-yl)phenyl]pyridine-3-carboxamide
CAS 573948-93-3C23H24N4O
N-{4-[4-(2-Fluorobenzyl)piperazin-1-yl]phenyl}pyridine-3-carboxamide chemical structure, C23H23FN4O, CAS 708989-88-2
N-{4-[4-(2-Fluorobenzyl)piperazin-1-yl]phenyl}pyridine-3-carboxamide
CAS 708989-88-2C23H23FN4O
N-{4-[4-(2-Chlorobenzyl)-1-piperazinyl]phenyl}nicotinamide chemical structure, C23H23ClN4O, CAS 694451-13-3
N-{4-[4-(2-Chlorobenzyl)-1-piperazinyl]phenyl}nicotinamide
CAS 694451-13-3C23H23ClN4O
N-[4-(4-Benzylpiperazin-1-yl)phenyl]-2-(methylsulfanyl)pyridine-3-carboxamide chemical structure, C24H26N4OS, CAS 871322-49-5
N-[4-(4-Benzylpiperazin-1-yl)phenyl]-2-(methylsulfanyl)pyridine-3-carboxamide
CAS 871322-49-5C24H26N4OS