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Murcko scaffold

Ring system with 4 rings and 23 atoms

3 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
3
With full pages
1
Scaffold SMILES

c1ccc(NC2CCNc3ccc(-c4ccccc4)cc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(NC2CCNc3ccc(-c4ccccc4)cc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 3 of 3 chemicals

4-[(2s,4r)-1-Acetyl-4-[(4-Chlorophenyl)amino]-2-Methyl-1,2,3,4-Tetrahydroquinolin-6-Yl]benzoic Acid chemical structure, C25H23ClN2O3, CAS 1300031-52-0
4-[(2s,4r)-1-Acetyl-4-[(4-Chlorophenyl)amino]-2-Methyl-1,2,3,4-Tetrahydroquinolin-6-Yl]benzoic Acid
CAS 1300031-52-0C25H23ClN2O3
Bromodomain inhibitor-8 chemical structure, C26H25ClN2O3, CAS 1300031-70-2
Bromodomain inhibitor-8
CAS 1300031-70-2C26H25ClN2O3
Methyl 4-[[(2S,4R)-6-(3-acetamidophenyl)-1-acetyl-2-methyl-3,4-dihydro-2H-quinolin-4-yl]amino]benzoate chemical structure, C28H29N3O4, CAS 2230675-71-3
Methyl 4-[[(2S,4R)-6-(3-acetamidophenyl)-1-acetyl-2-methyl-3,4-dihydro-2H-quinolin-4-yl]amino]benzoate
CAS 2230675-71-3C28H29N3O4