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Murcko scaffold

3H,4H-Pyrido(2,3-b)pyrazin-3-one scaffold

45 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 11
Chemicals: 45
With full pages: 5

Scaffold SMILES

O=c1cnc2cccnc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 3H,4H-Pyrido(2,3-b)pyrazin-3-one page

Murcko scaffold O=c1cnc2cccnc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 45 of 45 chemicals

Ethyl 3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-2-carboxylate chemical structure, C10H9N3O3, CAS 114097-17-5

Ethyl 3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-2-carboxylate

CAS 114097-17-5C₁₀H₉N₃O₃

Ethyl 4-methyl-3-oxopyrido[2,3-b]pyrazine-2-carboxylate chemical structure, C11H11N3O3, CAS 1471-86-9

Ethyl 4-methyl-3-oxopyrido[2,3-b]pyrazine-2-carboxylate

CAS 1471-86-9C₁₁H₁₁N₃O₃

Pyrido(2,3-b)pyrazin-3(4H)-one, 4-(2-(dimethylamino)ethyl)-2-methyl- chemical structure, C12H16N4O, CAS 86004-86-6

Pyrido(2,3-b)pyrazin-3(4H)-one, 4-(2-(dimethylamino)ethyl)-2-methyl-

CAS 86004-86-6C₁₂H₁₆N₄O

2-(Trifluoromethyl)pyrido[2,3-b]pyrazin-3(4H)-one chemical structure, C8H4F3N3O, CAS 143309-81-3

2-(Trifluoromethyl)pyrido[2,3-b]pyrazin-3(4H)-one

CAS 143309-81-3C₈H₄F₃N₃O

4-Methyl-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-2-carboxylic acid chemical structure, C9H7N3O3, CAS 114163-38-1

4-Methyl-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-2-carboxylic acid

CAS 114163-38-1C₉H₇N₃O₃

2-Chloro-4-methylpyrido[2,3-b]pyrazin-3(4H)-one chemical structure, C8H6ClN3O, CAS 80708-26-5

2-Chloro-4-methylpyrido[2,3-b]pyrazin-3(4H)-one

CAS 80708-26-5C₈H₆ClN₃O

2-Methylpyrido[2,3-b]pyrazin-3(4H)-one chemical structure, C8H7N3O, CAS 128102-80-7

2-Methylpyrido[2,3-b]pyrazin-3(4H)-one

CAS 128102-80-7C₈H₇N₃O

2-Aminopyrido[2,3-b]pyrazin-3(4H)-one chemical structure, C7H6N4O, CAS 190144-15-1

2-Aminopyrido[2,3-b]pyrazin-3(4H)-one

CAS 190144-15-1C₇H₆N₄O

3H,4H-Pyrido(2,3-b)pyrazin-3-one chemical structure, C7H5N3O, CAS 35252-02-9

3H,4H-Pyrido(2,3-b)pyrazin-3-one

CAS 35252-02-9C₇H₅N₃O

2,4-Dimethylpyrido[3,2-b]pyrazin-3(4H)-one chemical structure, C9H9N3O, CAS 1195679-13-0

2,4-Dimethylpyrido[3,2-b]pyrazin-3(4H)-one

CAS 1195679-13-0C₉H₉N₃O

2-Chloro-4-propylpyrido[2,3-b]pyrazin-3(4H)-one chemical structure, C10H10ClN3O, CAS 1170410-91-9

2-Chloro-4-propylpyrido[2,3-b]pyrazin-3(4H)-one

CAS 1170410-91-9C₁₀H₁₀ClN₃O

2-(Propan-2-yl)pyrido[2,3-b]pyrazin-3(4H)-one chemical structure, C10H11N3O, CAS 179123-10-5

2-(Propan-2-yl)pyrido[2,3-b]pyrazin-3(4H)-one

CAS 179123-10-5C₁₀H₁₁N₃O

2,6,8-Trimethylpyrido[2,3-b]pyrazin-3(4H)-one chemical structure, C10H11N3O, CAS 151027-83-7

2,6,8-Trimethylpyrido[2,3-b]pyrazin-3(4H)-one

CAS 151027-83-7C₁₀H₁₁N₃O

[(3-Oxo-4-propyl-3,4-dihydropyrido[2,3-b]pyrazin-2-yl)thio]acetic acid chemical structure, C12H13N3O3S, CAS 1243105-87-4

[(3-Oxo-4-propyl-3,4-dihydropyrido[2,3-b]pyrazin-2-yl)thio]acetic acid

CAS 1243105-87-4C₁₂H₁₃N₃O₃S

[(4-Isobutyl-3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-2-yl)thio]acetic acid chemical structure, C13H15N3O3S, CAS 1242960-73-1

[(4-Isobutyl-3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-2-yl)thio]acetic acid

CAS 1242960-73-1C₁₃H₁₅N₃O₃S

[(4-Ethyl-3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-2-yl)thio]acetic acid chemical structure, C11H11N3O3S, CAS 1242884-38-3

[(4-Ethyl-3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-2-yl)thio]acetic acid

CAS 1242884-38-3C₁₁H₁₁N₃O₃S

7-Bromo-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-2-carboxylic acid chemical structure, C8H4BrN3O3, CAS 38508-43-9

7-Bromo-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-2-carboxylic acid

CAS 38508-43-9C₈H₄BrN₃O₃

4-(2,2-Dimethoxyethyl)-6-methoxypyrido[2,3-b]pyrazin-3(4H)-one chemical structure, C12H15N3O4, CAS 1003945-84-3

4-(2,2-Dimethoxyethyl)-6-methoxypyrido[2,3-b]pyrazin-3(4H)-one

CAS 1003945-84-3C₁₂H₁₅N₃O₄

Pyrido[2,3-b]pyrazine-2-carboxylic acid, 3,4-dihydro-3-oxo- chemical structure, C8H5N3O3, CAS 35188-04-6

Pyrido[2,3-b]pyrazine-2-carboxylic acid, 3,4-dihydro-3-oxo-

CAS 35188-04-6C₈H₅N₃O₃

6-Amino-3-hydroxy-pyrido[2,3-B]pyrazine-2-carboxylic acid chemical structure, C8H6N4O3, CAS 874493-62-6

6-Amino-3-hydroxy-pyrido[2,3-B]pyrazine-2-carboxylic acid

CAS 874493-62-6C₈H₆N₄O₃

7-Bromo-3H,4H-pyrido(2,3-b)pyrazin-3-one chemical structure, C7H4BrN3O, CAS 957107-12-9

7-Bromo-3H,4H-pyrido(2,3-b)pyrazin-3-one

CAS 957107-12-9C₇H₄BrN₃O

6-Amino-3H,4H-pyrido[2,3-b]pyrazin-3-one chemical structure, C7H6N4O, CAS 874493-61-5

6-Amino-3H,4H-pyrido[2,3-b]pyrazin-3-one

CAS 874493-61-5C₇H₆N₄O

(3-Oxopyrido(2,3-b)pyrazin-4(3H)-yl)acetaldehyde chemical structure, C9H7N3O2, CAS 959615-96-4

(3-Oxopyrido(2,3-b)pyrazin-4(3H)-yl)acetaldehyde

CAS 959615-96-4C₉H₇N₃O₂

(6-Methoxy-3-oxopyrido(2,3-b)pyrazin-4(3H)-yl)acetaldehyde chemical structure, C10H9N3O3, CAS 959615-77-1

(6-Methoxy-3-oxopyrido(2,3-b)pyrazin-4(3H)-yl)acetaldehyde

CAS 959615-77-1C₁₀H₉N₃O₃