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Murcko scaffold

Ring system with 6 rings and 31 atoms

8 chemicals on CompoundList share this ring system.

Rings
6
Scaffold atoms
31
Chemicals
8
With full pages
5
Scaffold SMILES

O=C(c1cccc2ccccc12)c1cn2c3c(cccc13)OCC2CN1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1cccc2ccccc12)c1cn2c3c(cccc13)OCC2CN1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

(5-Methyl-3-(morpholinomethyl)-2,3-dihydro-[1,4]oxazino[2,3,4-hi]indol-6-yl)(naphthalen-1-yl)methanone chemical structure, C27H26N2O3, CAS 131513-18-3
(5-Methyl-3-(morpholinomethyl)-2,3-dihydro-[1,4]oxazino[2,3,4-hi]indol-6-yl)(naphthalen-1-yl)methanone
CAS 131513-18-3C27H26N2O3
Win 55212-2 chemical structure, C27H26N2O3, CAS 131543-22-1
Win 55212-2
CAS 131543-22-1C27H26N2O3
WIN-55212-2 mesylate chemical structure, C28H30N2O6S, CAS 131543-23-2
WIN-55212-2 mesylate
CAS 131543-23-2C28H30N2O6S
Methanone, (2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo(1,2,3-de)-1,4-benzoxazin-6-yl)-1-naphthalenyl-, (S)- chemical structure, C27H26N2O3, CAS 131543-24-3
Methanone, (2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo(1,2,3-de)-1,4-benzoxazin-6-yl)-1-naphthalenyl-, (S)-
CAS 131543-24-3C27H26N2O3
R23Dtw852D chemical structure, C27H26N2O3, CAS 263903-88-4
R23Dtw852D
CAS 263903-88-4C27H26N2O3
S(-)-WIN 55,212-3 mesylate salt chemical structure, C28H30N2O6S, CAS 131543-25-4
S(-)-WIN 55,212-3 mesylate salt
CAS 131543-25-4C28H30N2O6S
(5,7-Dibromonaphthalen-1-yl)-[(11R)-2-methyl-11-(morpholin-4-ylmethyl)-9-oxa-1-azatricyclo[6.3.1.04,12]dodeca-2,4(12),5,7-tetraen-3-yl]methanone chemical structure, C27H24Br2N2O3, CAS 131513-21-8
(5,7-Dibromonaphthalen-1-yl)-[(11R)-2-methyl-11-(morpholin-4-ylmethyl)-9-oxa-1-azatricyclo[6.3.1.04,12]dodeca-2,4(12),5,7-tetraen-3-yl]methanone
CAS 131513-21-8C27H24Br2N2O3
(2,3-Dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl)methanone monomethanesulfonate chemical structure, C28H30N2O6S, CAS 137795-17-6
(2,3-Dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl)methanone monomethanesulfonate
CAS 137795-17-6C28H30N2O6S