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Murcko scaffold

Ring system with 3 rings and 17 atoms

43 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
43
With full pages
9
Scaffold SMILES

O=C1CC(c2ccccc2)c2ccccc2O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC(c2ccccc2)c2ccccc2O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 43 of 43 chemicals

7-Hydroxy-4-phenyl-2-chromanone chemical structure, C15H12O3, CAS 6275-80-5
7-Hydroxy-4-phenyl-2-chromanone
CAS 6275-80-5C15H12O3
4-(3,4-Dimethoxyphenyl)-7-methoxy-2-chromanone chemical structure, C18H18O5, CAS 35582-80-0
4-(3,4-Dimethoxyphenyl)-7-methoxy-2-chromanone
CAS 35582-80-0C18H18O5
(S)-7-Methyl-4-phenylchroman-2-one chemical structure, C16H14O2, CAS 1802842-71-2
(S)-7-Methyl-4-phenylchroman-2-one
CAS 1802842-71-2C16H14O2
(4R)-6-Methyl-4-phenyl-3,4-dihydro-2H-1-benzopyran-2-one chemical structure, C16H14O2, CAS 827007-19-2
(4R)-6-Methyl-4-phenyl-3,4-dihydro-2H-1-benzopyran-2-one
CAS 827007-19-2C16H14O2
(4s)-6-Methyl-4-phenylchroman-2-one chemical structure, C16H14O2, CAS 349547-18-8
(4s)-6-Methyl-4-phenylchroman-2-one
CAS 349547-18-8C16H14O2
7,8-Dimethyl-4-phenylchroman-2-one chemical structure, C17H16O2, CAS 331964-82-0
7,8-Dimethyl-4-phenylchroman-2-one
CAS 331964-82-0C17H16O2
7-Methyl-4-phenyl-3,4-dihydrochromen-2-one chemical structure, C16H14O2, CAS 88407-29-8
7-Methyl-4-phenyl-3,4-dihydrochromen-2-one
CAS 88407-29-8C16H14O2
6-Bromo-3,4-dihydro-4-phenyl-2H-1-benzopyran-2-one chemical structure, C15H11BrO2, CAS 156755-23-6
6-Bromo-3,4-dihydro-4-phenyl-2H-1-benzopyran-2-one
CAS 156755-23-6C15H11BrO2
8-Methyl-4-phenyl-3,4-dihydrochromen-2-one chemical structure, C16H14O2, CAS 103391-81-7
8-Methyl-4-phenyl-3,4-dihydrochromen-2-one
CAS 103391-81-7C16H14O2
4-(4-Chlorophenyl)-5,7-dihydroxy-2-chromanone chemical structure, C15H11ClO4, CAS 338417-72-4
4-(4-Chlorophenyl)-5,7-dihydroxy-2-chromanone
CAS 338417-72-4C15H11ClO4
5,7-Dihydroxy-4-phenyl-2-chromanone chemical structure, C15H12O4, CAS 108013-15-6
5,7-Dihydroxy-4-phenyl-2-chromanone
CAS 108013-15-6C15H12O4
6-Methyl-4-phenyl-3,4-dihydrochromen-2-one chemical structure, C16H14O2, CAS 40546-94-9
6-Methyl-4-phenyl-3,4-dihydrochromen-2-one
CAS 40546-94-9C16H14O2
2H-1-Benzopyran-2-one, 3,4-dihydro-6-hydroxy-4-phenyl- chemical structure, C15H12O3, CAS 57322-71-1
2H-1-Benzopyran-2-one, 3,4-dihydro-6-hydroxy-4-phenyl-
CAS 57322-71-1C15H12O3
6-Ethyl-4-phenylchroman-2-one chemical structure, C17H16O2, CAS 405277-43-2
6-Ethyl-4-phenylchroman-2-one
CAS 405277-43-2C17H16O2
6-Chloro-3,4-dihydro-4-phenyl-2H-1-Benzopyran-2-one chemical structure, C15H11ClO2, CAS 73108-72-2
6-Chloro-3,4-dihydro-4-phenyl-2H-1-Benzopyran-2-one
CAS 73108-72-2C15H11ClO2
6-Carboxyl-4-phenyl-3,4-dihydrocoumarin chemical structure, C16H12O4, CAS 356782-33-7
6-Carboxyl-4-phenyl-3,4-dihydrocoumarin
CAS 356782-33-7C16H12O4
3,4-Dihydro-6-methoxy-4-phenyl-2H-1-benzopyran-2-one chemical structure, C16H14O3, CAS 40546-95-0
3,4-Dihydro-6-methoxy-4-phenyl-2H-1-benzopyran-2-one
CAS 40546-95-0C16H14O3
Methyl (4R)-2-oxo-4-phenyl-3,4-dihydro-2H-chromene-6-carboxylate chemical structure, C17H14O4, CAS 854626-79-2
Methyl (4R)-2-oxo-4-phenyl-3,4-dihydro-2H-chromene-6-carboxylate
CAS 854626-79-2C17H14O4
3,4-Dihydro-7-methoxy-4-(4-methoxyphenyl)-2H-1-benzopyran-2-one chemical structure, C17H16O4, CAS 109386-29-0
3,4-Dihydro-7-methoxy-4-(4-methoxyphenyl)-2H-1-benzopyran-2-one
CAS 109386-29-0C17H16O4
3,4-Dihydro-5,7-dimethoxy-4-phenyl-2H-1-benzopyran-2-one chemical structure, C17H16O4, CAS 854897-58-8
3,4-Dihydro-5,7-dimethoxy-4-phenyl-2H-1-benzopyran-2-one
CAS 854897-58-8C17H16O4
2H-1-Benzopyran-2-one, 3,4-dihydro-4-phenyl-, (4R)- chemical structure, C15H12O2, CAS 732250-35-0
2H-1-Benzopyran-2-one, 3,4-dihydro-4-phenyl-, (4R)-
CAS 732250-35-0C15H12O2
(4S)-4-Phenyl-3,4-dihydrochromen-2-one chemical structure, C15H12O2, CAS 61198-52-5
(4S)-4-Phenyl-3,4-dihydrochromen-2-one
CAS 61198-52-5C15H12O2
5,7-Dimethyl-4-phenyl-3,4-dihydro-2H-1-benzopyran-2-one chemical structure, C17H16O2, CAS 75164-84-0
5,7-Dimethyl-4-phenyl-3,4-dihydro-2H-1-benzopyran-2-one
CAS 75164-84-0C17H16O2
6,8-Dimethyl-4-phenyl-3,4-dihydro-2H-1-benzopyran-2-one chemical structure, C17H16O2, CAS 60813-66-3
6,8-Dimethyl-4-phenyl-3,4-dihydro-2H-1-benzopyran-2-one
CAS 60813-66-3C17H16O2