CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 17 atoms

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
5
With full pages
2
Scaffold SMILES

C=C1C2CCC1C(C(=O)Nc1ccccc1)C2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C=C1C2CCC1C(C(=O)Nc1ccccc1)C2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

2-[(4-Ethoxycarbonylphenyl)carbamoyl]-7-propan-2-ylidenebicyclo[2.2.1]heptane-3-carboxylic acid chemical structure, C21H25NO5, CAS 345347-82-2
2-[(4-Ethoxycarbonylphenyl)carbamoyl]-7-propan-2-ylidenebicyclo[2.2.1]heptane-3-carboxylic acid
CAS 345347-82-2C21H25NO5
3-((4-Methoxyphenyl)carbamoyl)-7-(propan-2-ylidene)bicyclo[2.2.1]heptane-2-carboxylic acid chemical structure, C19H23NO4, CAS 489450-04-6
3-((4-Methoxyphenyl)carbamoyl)-7-(propan-2-ylidene)bicyclo[2.2.1]heptane-2-carboxylic acid
CAS 489450-04-6C19H23NO4
3-[(3,5-Dimethylanilino)carbonyl]-7-(1-methylethylidene)bicyclo[2.2.1]heptane-2-carboxylic acid chemical structure, C20H25NO3, CAS 473446-97-8
3-[(3,5-Dimethylanilino)carbonyl]-7-(1-methylethylidene)bicyclo[2.2.1]heptane-2-carboxylic acid
CAS 473446-97-8C20H25NO3
3-[(4-Ethoxyphenyl)carbamoyl]-7-(propan-2-ylidene)bicyclo[2.2.1]heptane-2-carboxylic acid chemical structure, C20H25NO4, CAS 6132-49-6
3-[(4-Ethoxyphenyl)carbamoyl]-7-(propan-2-ylidene)bicyclo[2.2.1]heptane-2-carboxylic acid
CAS 6132-49-6C20H25NO4
2-[(2,5-Dimethoxyphenyl)carbamoyl]-7-propan-2-ylidenebicyclo[2.2.1]heptane-3-carboxylic acid chemical structure, C20H25NO5, CAS 345288-50-8
2-[(2,5-Dimethoxyphenyl)carbamoyl]-7-propan-2-ylidenebicyclo[2.2.1]heptane-3-carboxylic acid
CAS 345288-50-8C20H25NO5