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Murcko scaffold

Ring system with 3 rings and 16 atoms

48 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
48
With full pages
24
Scaffold SMILES

O=C(Nc1ccccc1)C1CC2CCC1C2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)C1CC2CCC1C2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

N-(4-Iodo-2-methylphenyl)bicyclo[2.2.1]heptane-2-carboxamide chemical structure, C15H18INO, CAS 468093-71-2
N-(4-Iodo-2-methylphenyl)bicyclo[2.2.1]heptane-2-carboxamide
CAS 468093-71-2C15H18INO
N-[3-(Trifluoromethyl)phenyl]bicyclo[2.2.1]heptane-2-carboxamide chemical structure, C15H16F3NO, CAS 464923-29-3
N-[3-(Trifluoromethyl)phenyl]bicyclo[2.2.1]heptane-2-carboxamide
CAS 464923-29-3C15H16F3NO
N-[3-(Acetylamino)phenyl]bicyclo[2.2.1]heptane-2-carboxamide chemical structure, C16H20N2O2, CAS 468090-20-2
N-[3-(Acetylamino)phenyl]bicyclo[2.2.1]heptane-2-carboxamide
CAS 468090-20-2C16H20N2O2
N-(2-Methyl-5-sulfamoylphenyl)bicyclo[2.2.1]heptane-2-carboxamide chemical structure, C15H20N2O3S, CAS 468093-55-2
N-(2-Methyl-5-sulfamoylphenyl)bicyclo[2.2.1]heptane-2-carboxamide
CAS 468093-55-2C15H20N2O3S
Ethyl 4-[(bicyclo[2.2.1]hept-2-ylcarbonyl)amino]benzoate chemical structure, C17H21NO3, CAS 468714-43-4
Ethyl 4-[(bicyclo[2.2.1]hept-2-ylcarbonyl)amino]benzoate
CAS 468714-43-4C17H21NO3
N-(3-Chloro-4-fluorophenyl)bicyclo[2.2.1]heptane-2-carboxamide chemical structure, C14H15ClFNO, CAS 468714-26-3
N-(3-Chloro-4-fluorophenyl)bicyclo[2.2.1]heptane-2-carboxamide
CAS 468714-26-3C14H15ClFNO
N-(4-Chloro-2,5-dimethoxyphenyl)bicyclo[2.2.1]heptane-2-carboxamide chemical structure, C16H20ClNO3, CAS 468714-37-6
N-(4-Chloro-2,5-dimethoxyphenyl)bicyclo[2.2.1]heptane-2-carboxamide
CAS 468714-37-6C16H20ClNO3
N-(3,5-Dimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamide chemical structure, C16H21NO, CAS 471289-36-8
N-(3,5-Dimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamide
CAS 471289-36-8C16H21NO
N-(2,4-Difluorophenyl)bicyclo[2.2.1]heptane-2-carboxamide chemical structure, C14H15F2NO, CAS 468744-12-9
N-(2,4-Difluorophenyl)bicyclo[2.2.1]heptane-2-carboxamide
CAS 468744-12-9C14H15F2NO
N-(4-Ethoxyphenyl)bicyclo[2.2.1]heptane-2-carboxamide chemical structure, C16H21NO2, CAS 471290-29-6
N-(4-Ethoxyphenyl)bicyclo[2.2.1]heptane-2-carboxamide
CAS 471290-29-6C16H21NO2
3-[(3-Acetylphenyl)carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid chemical structure, C17H19NO4, CAS 353524-14-8
3-[(3-Acetylphenyl)carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid
CAS 353524-14-8C17H19NO4
3-(4-Acetyl-phenylcarbamoyl)-bicyclo[2.2.1]heptane-2-carboxylic acid chemical structure, C17H19NO4, CAS 353524-11-5
3-(4-Acetyl-phenylcarbamoyl)-bicyclo[2.2.1]heptane-2-carboxylic acid
CAS 353524-11-5C17H19NO4
3-({4-[(2-Methylpropoxy)carbonyl]phenyl}carbamoyl)bicyclo[2.2.1]heptane-2-carboxylic acid chemical structure, C20H25NO5, CAS 499995-33-4
3-({4-[(2-Methylpropoxy)carbonyl]phenyl}carbamoyl)bicyclo[2.2.1]heptane-2-carboxylic acid
CAS 499995-33-4C20H25NO5
3-[(3-Nitrophenyl)carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid chemical structure, C15H16N2O5, CAS 353524-09-1
3-[(3-Nitrophenyl)carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid
CAS 353524-09-1C15H16N2O5
3-[(4-Carboxyphenyl)carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid chemical structure, C16H17NO5, CAS 353524-15-9
3-[(4-Carboxyphenyl)carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid
CAS 353524-15-9C16H17NO5
3-(Phenylcarbamoyl)bicyclo[2.2.1]heptane-2-carboxylic acid chemical structure, C15H17NO3, CAS 488786-12-5
3-(Phenylcarbamoyl)bicyclo[2.2.1]heptane-2-carboxylic acid
CAS 488786-12-5C15H17NO3
3-{[4-(Acetylamino)anilino]carbonyl}bicyclo[2.2.1]heptane-2-carboxylic acid chemical structure, C17H20N2O4, CAS 353524-13-7
3-{[4-(Acetylamino)anilino]carbonyl}bicyclo[2.2.1]heptane-2-carboxylic acid
CAS 353524-13-7C17H20N2O4
2-[(4-Ethoxycarbonylphenyl)carbamoyl]bicyclo[2.2.1]heptane-3-carboxylic acid chemical structure, C18H21NO5, CAS 353524-10-4
2-[(4-Ethoxycarbonylphenyl)carbamoyl]bicyclo[2.2.1]heptane-3-carboxylic acid
CAS 353524-10-4C18H21NO5
N-(4-Fluoro-3-nitrophenyl)bicyclo[2.2.1]heptane-2-carboxamide chemical structure, C14H15FN2O3, CAS 357932-87-7
N-(4-Fluoro-3-nitrophenyl)bicyclo[2.2.1]heptane-2-carboxamide
CAS 357932-87-7C14H15FN2O3
Ethyl 2-[(bicyclo[2.2.1]hept-2-ylcarbonyl)amino]benzoate chemical structure, C17H21NO3, CAS 473444-97-2
Ethyl 2-[(bicyclo[2.2.1]hept-2-ylcarbonyl)amino]benzoate
CAS 473444-97-2C17H21NO3
3-[(2,5-Dimethoxyphenyl)carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid chemical structure, C17H21NO5, CAS 489452-05-3
3-[(2,5-Dimethoxyphenyl)carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid
CAS 489452-05-3C17H21NO5
3-((5-Carboxy-2-methylphenyl)carbamoyl)bicyclo[2.2.1]heptane-2-carboxylic acid chemical structure, C17H19NO5, CAS 318466-18-1
3-((5-Carboxy-2-methylphenyl)carbamoyl)bicyclo[2.2.1]heptane-2-carboxylic acid
CAS 318466-18-1C17H19NO5
3-[(3,4-Dimethoxyanilino)carbonyl]bicyclo[2.2.1]heptane-2-carboxylic acid chemical structure, C17H21NO5, CAS 489451-93-6
3-[(3,4-Dimethoxyanilino)carbonyl]bicyclo[2.2.1]heptane-2-carboxylic acid
CAS 489451-93-6C17H21NO5
3-[(2,4-Dimethoxyphenyl)carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid chemical structure, C17H21NO5, CAS 473446-99-0
3-[(2,4-Dimethoxyphenyl)carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid
CAS 473446-99-0C17H21NO5