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Murcko scaffold

Ring system with 3 rings and 16 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
15
With full pages
7
Scaffold SMILES

O=C(Nc1ccccc1)C1CC2C=CC1O2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)C1CC2C=CC1O2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

2-[(2-Ethylphenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-3-carboxylic acid chemical structure, C16H17NO4, CAS 1005110-92-8
2-[(2-Ethylphenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-3-carboxylic acid
CAS 1005110-92-8C16H17NO4
3-[(2-Methoxy-5-methylanilino)carbonyl]-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid chemical structure, C16H17NO5, CAS 470472-55-0
3-[(2-Methoxy-5-methylanilino)carbonyl]-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid
CAS 470472-55-0C16H17NO5
2-[(3,5-Dimethylphenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-3-carboxylic acid chemical structure, C16H17NO4, CAS 470472-63-0
2-[(3,5-Dimethylphenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-3-carboxylic acid
CAS 470472-63-0C16H17NO4
3-[(3,5-Dichlorophenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid chemical structure, C14H11Cl2NO4, CAS 54888-08-3
3-[(3,5-Dichlorophenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid
CAS 54888-08-3C14H11Cl2NO4
3-[(3-Chloro-4-fluorophenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid chemical structure, C14H11ClFNO4, CAS 473445-19-1
3-[(3-Chloro-4-fluorophenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid
CAS 473445-19-1C14H11ClFNO4
2-[(4-Bromophenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-3-carboxylic acid chemical structure, C14H12BrNO4, CAS 313343-47-4
2-[(4-Bromophenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-3-carboxylic acid
CAS 313343-47-4C14H12BrNO4
2-[(2-Fluorophenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-3-carboxylic acid chemical structure, C14H12FNO4, CAS 431036-01-0
2-[(2-Fluorophenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-3-carboxylic acid
CAS 431036-01-0C14H12FNO4
2-[(4-Butan-2-ylphenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-3-carboxylic acid chemical structure, C18H21NO4, CAS 1005132-94-4
2-[(4-Butan-2-ylphenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-3-carboxylic acid
CAS 1005132-94-4C18H21NO4
3-[(5-Chloro-2-methoxyanilino)carbonyl]-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid chemical structure, C15H14ClNO5, CAS 489407-49-0
3-[(5-Chloro-2-methoxyanilino)carbonyl]-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid
CAS 489407-49-0C15H14ClNO5
2-[(4-Chloro-3-nitrophenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-3-carboxylic acid chemical structure, C14H11ClN2O6, CAS 313343-46-3
2-[(4-Chloro-3-nitrophenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-3-carboxylic acid
CAS 313343-46-3C14H11ClN2O6
3-{[2-(Methoxycarbonyl)anilino]carbonyl}-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid chemical structure, C16H15NO6, CAS 489409-75-8
3-{[2-(Methoxycarbonyl)anilino]carbonyl}-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid
CAS 489409-75-8C16H15NO6
3-{[4-(Acetylsulfamoyl)phenyl]carbamoyl}-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid chemical structure, C16H16N2O7S, CAS 491831-84-6
3-{[4-(Acetylsulfamoyl)phenyl]carbamoyl}-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid
CAS 491831-84-6C16H16N2O7S
3-{[4-(Propoxycarbonyl)anilino]carbonyl}-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid chemical structure, C18H19NO6, CAS 491832-07-6
3-{[4-(Propoxycarbonyl)anilino]carbonyl}-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid
CAS 491832-07-6C18H19NO6
3-{[4-(Dimethylamino)phenyl]carbamoyl}-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid chemical structure, C16H18N2O4, CAS 470472-67-4
3-{[4-(Dimethylamino)phenyl]carbamoyl}-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid
CAS 470472-67-4C16H18N2O4
2-[(4-Ethylphenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-3-carboxylic acid chemical structure, C16H17NO4, CAS 6343-59-5
2-[(4-Ethylphenyl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-3-carboxylic acid
CAS 6343-59-5C16H17NO4