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Murcko scaffold

N-(2-Phenylethyl)pyrazine-2-carboxamide scaffold

63 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
63
With full pages
14
Scaffold SMILES

O=C(NCCc1ccccc1)c1cnccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(2-Phenylethyl)pyrazine-2-carboxamide page
Murcko scaffold O=C(NCCc1ccccc1)c1cnccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 63 chemicals

Bortezomib, (1S,2R)- chemical structure, C19H25BN4O4, CAS 1132709-16-0
Bortezomib, (1S,2R)-
CAS 1132709-16-0C19H25BN4O4
Bortezomib chemical structure, C19H25BN4O4, CAS 179324-69-7
Bortezomib
CAS 179324-69-7C19H25BN4O4
N-[(1S)-1-Benzyl-2-[[(1S)-1-formyl-3-methyl-butyl]amino]-2-oxo-ethyl]pyrazine-2-carboxamide chemical structure, C20H24N4O3, CAS 205393-16-4
N-[(1S)-1-Benzyl-2-[[(1S)-1-formyl-3-methyl-butyl]amino]-2-oxo-ethyl]pyrazine-2-carboxamide
CAS 205393-16-4C20H24N4O3
N-(2-Phenylethyl)pyrazine-2-carboxamide chemical structure, C13H13N3O, CAS 199477-92-4
N-(2-Phenylethyl)pyrazine-2-carboxamide
CAS 199477-92-4C13H13N3O
N-[2-(3,4-Dimethoxyphenyl)ethyl]pyrazine-2-carboxamide chemical structure, C15H17N3O3, CAS 543685-45-6
N-[2-(3,4-Dimethoxyphenyl)ethyl]pyrazine-2-carboxamide
CAS 543685-45-6C15H17N3O3
N-(3-Fluorophenethyl)pyrazine-2-carboxamide chemical structure, C13H12FN3O, CAS 606132-08-5
N-(3-Fluorophenethyl)pyrazine-2-carboxamide
CAS 606132-08-5C13H12FN3O
N-(2-Fluorophenethyl)pyrazine-2-carboxamide chemical structure, C13H12FN3O, CAS 606132-09-6
N-(2-Fluorophenethyl)pyrazine-2-carboxamide
CAS 606132-09-6C13H12FN3O
N-(4-Fluorophenethyl)pyrazine-2-carboxamide chemical structure, C13H12FN3O, CAS 606132-11-0
N-(4-Fluorophenethyl)pyrazine-2-carboxamide
CAS 606132-11-0C13H12FN3O
Pyrazinecarboxamide, 5-methyl-N-(2-phenylethyl)- chemical structure, C14H15N3O, CAS 591254-76-1
Pyrazinecarboxamide, 5-methyl-N-(2-phenylethyl)-
CAS 591254-76-1C14H15N3O
5-Methyl-N-[2-[4-(trifluoromethyl)phenyl]ethyl]pyrazine-2-carboxamide chemical structure, C15H14F3N3O, CAS 867282-36-8
5-Methyl-N-[2-[4-(trifluoromethyl)phenyl]ethyl]pyrazine-2-carboxamide
CAS 867282-36-8C15H14F3N3O
N-[2-(3,4-Dimethoxyphenyl)ethyl]-N,5-dimethylpyrazine-2-carboxamide chemical structure, C17H21N3O3, CAS 923856-20-6
N-[2-(3,4-Dimethoxyphenyl)ethyl]-N,5-dimethylpyrazine-2-carboxamide
CAS 923856-20-6C17H21N3O3
4-(2-(5-Methylpyrazine-2-carboxamido)ethyl)benzenesulfonamide chemical structure, C14H16N4O3S, CAS 33288-71-0
4-(2-(5-Methylpyrazine-2-carboxamido)ethyl)benzenesulfonamide
CAS 33288-71-0C14H16N4O3S
Methyl N-(pyrazine-2-carbonyl)phenylalaninate chemical structure, C15H15N3O3
Methyl N-(pyrazine-2-carbonyl)phenylalaninate
C15H15N3O3
(S)-Methyl 3-phenyl-2-(pyrazine-2-carboxamido)propanoate chemical structure, C15H15N3O3, CAS 73058-37-4
(S)-Methyl 3-phenyl-2-(pyrazine-2-carboxamido)propanoate
CAS 73058-37-4C15H15N3O3
Methyl ((4-(2-(((5-methylpyrazin-2-yl)carbonyl)amino)ethyl)phenyl)sulfonyl)carbamate chemical structure, C16H18N4O5S, CAS 33288-74-3
Methyl ((4-(2-(((5-methylpyrazin-2-yl)carbonyl)amino)ethyl)phenyl)sulfonyl)carbamate
CAS 33288-74-3C16H18N4O5S
N-Des(cyclohexylaminocarbonyl)-N-acetyl Glipizide chemical structure, C16H18N4O4S, CAS 104838-12-2
N-Des(cyclohexylaminocarbonyl)-N-acetyl Glipizide
CAS 104838-12-2C16H18N4O4S
N-(Pyrazinylcarbonyl)-L-phenylalanine chemical structure, C14H13N3O3, CAS 114457-94-2
N-(Pyrazinylcarbonyl)-L-phenylalanine
CAS 114457-94-2C14H13N3O3
3-(4-Hydroxyphenyl)-2-(pyrazin-2-ylformamido)propanoic acid chemical structure, C14H13N3O4, CAS 1396980-05-4
3-(4-Hydroxyphenyl)-2-(pyrazin-2-ylformamido)propanoic acid
CAS 1396980-05-4C14H13N3O4
N-(Pyrazine-2-yl-carbonyl)-L-phenylalanine chemical structure, C14H13N3O3, CAS 1093959-75-1
N-(Pyrazine-2-yl-carbonyl)-L-phenylalanine
CAS 1093959-75-1C14H13N3O3
N-[2-(4-Chlorophenyl)ethyl]-5-methylpyrazine-2-carboxamide chemical structure, C14H14ClN3O, CAS 1007831-83-5
N-[2-(4-Chlorophenyl)ethyl]-5-methylpyrazine-2-carboxamide
CAS 1007831-83-5C14H14ClN3O
N-[2-[4-Chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide chemical structure, C14H14ClN3O3S, CAS 66376-00-9
N-[2-[4-Chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide
CAS 66376-00-9C14H14ClN3O3S
((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid chemical structure, C19H25BN4O4, CAS 1132709-14-8
((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid
CAS 1132709-14-8C19H25BN4O4
3-Amino-N-[2-(4-chlorophenyl)ethyl]-2-pyrazinecarboxamide chemical structure, C13H13ClN4O, CAS 1030178-97-2
3-Amino-N-[2-(4-chlorophenyl)ethyl]-2-pyrazinecarboxamide
CAS 1030178-97-2C13H13ClN4O
Ethyl (4-{2-[(5-methylpyrazine-2-carbonyl)amino]ethyl}benzene-1-sulfonyl)carbamate chemical structure, C17H20N4O5S, CAS 1076198-09-8
Ethyl (4-{2-[(5-methylpyrazine-2-carbonyl)amino]ethyl}benzene-1-sulfonyl)carbamate
CAS 1076198-09-8C17H20N4O5S