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Murcko scaffold

3,5-Diphenyl-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazole scaffold

213 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
213
With full pages
9
Scaffold SMILES

O=S(=O)(c1ccccc1)N1N=C(c2ccccc2)CC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3,5-Diphenyl-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazole page
Murcko scaffold O=S(=O)(c1ccccc1)N1N=C(c2ccccc2)CC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 213 chemicals

1-[(4-Methylphenyl)sulfonyl]-3,5-diphenyl-4,5-dihydro-1H-pyrazole chemical structure, C22H20N2O2S, CAS 20409-91-0
1-[(4-Methylphenyl)sulfonyl]-3,5-diphenyl-4,5-dihydro-1H-pyrazole
CAS 20409-91-0C22H20N2O2S
5-(4-Methoxyphenyl)-3-phenyl-1-tosyl-4,5-dihydro-1H-pyrazole chemical structure, C23H22N2O3S, CAS 361170-78-7
5-(4-Methoxyphenyl)-3-phenyl-1-tosyl-4,5-dihydro-1H-pyrazole
CAS 361170-78-7C23H22N2O3S
3-(4-Methoxyphenyl)-1-[(4-methylphenyl)sulfonyl]-5-(3-nitrophenyl)-4,5-dihydro-1H-pyrazole chemical structure, C23H21N3O5S, CAS 330202-25-0
3-(4-Methoxyphenyl)-1-[(4-methylphenyl)sulfonyl]-5-(3-nitrophenyl)-4,5-dihydro-1H-pyrazole
CAS 330202-25-0C23H21N3O5S
3,5-Bis(4-methoxyphenyl)-2-(4-methylphenyl)sulfonyl-3,4-dihydropyrazole chemical structure, C24H24N2O4S, CAS 313398-39-9
3,5-Bis(4-methoxyphenyl)-2-(4-methylphenyl)sulfonyl-3,4-dihydropyrazole
CAS 313398-39-9C24H24N2O4S
2-(Benzenesulfonyl)-5-(4-bromophenyl)-3-(4-methylphenyl)-3,4-dihydropyrazole chemical structure, C22H19BrN2O2S, CAS 377761-91-6
2-(Benzenesulfonyl)-5-(4-bromophenyl)-3-(4-methylphenyl)-3,4-dihydropyrazole
CAS 377761-91-6C22H19BrN2O2S
3-(3,4-Dimethoxyphenyl)-1-(phenylsulfonyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazole chemical structure, C24H24N2O4S, CAS 383893-26-3
3-(3,4-Dimethoxyphenyl)-1-(phenylsulfonyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazole
CAS 383893-26-3C24H24N2O4S
4-[2-(Benzenesulfonyl)-5-(4-chlorophenyl)-3,4-dihydropyrazol-3-yl]-N,N-dimethylaniline chemical structure, C23H22ClN3O2S, CAS 488118-98-5
4-[2-(Benzenesulfonyl)-5-(4-chlorophenyl)-3,4-dihydropyrazol-3-yl]-N,N-dimethylaniline
CAS 488118-98-5C23H22ClN3O2S
3,5-Diphenyl-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazole chemical structure, C21H18N2O2S, CAS 70958-23-5
3,5-Diphenyl-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazole
CAS 70958-23-5C21H18N2O2S
N-[3-[2-(Benzenesulfonyl)-3-(2-methylphenyl)-3,4-dihydropyrazol-5-yl]phenyl]ethanesulfonamide chemical structure, C24H25N3O4S2, CAS 714263-25-9
N-[3-[2-(Benzenesulfonyl)-3-(2-methylphenyl)-3,4-dihydropyrazol-5-yl]phenyl]ethanesulfonamide
CAS 714263-25-9C24H25N3O4S2
N-(4-(5-(3-Fluorophenyl)-1-tosyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C24H24FN3O4S2, CAS 714263-28-2
N-(4-(5-(3-Fluorophenyl)-1-tosyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 714263-28-2C24H24FN3O4S2
N-[3-[2-(Benzenesulfonyl)-3-(2-methylphenyl)-3,4-dihydropyrazol-5-yl]phenyl]methanesulfonamide chemical structure, C23H23N3O4S2, CAS 832684-22-7
N-[3-[2-(Benzenesulfonyl)-3-(2-methylphenyl)-3,4-dihydropyrazol-5-yl]phenyl]methanesulfonamide
CAS 832684-22-7C23H23N3O4S2
N-[4-[2-(4-Methoxyphenyl)sulfonyl-3-(2-methylphenyl)-3,4-dihydropyrazol-5-yl]phenyl]methanesulfonamide chemical structure, C24H25N3O5S2, CAS 833430-19-6
N-[4-[2-(4-Methoxyphenyl)sulfonyl-3-(2-methylphenyl)-3,4-dihydropyrazol-5-yl]phenyl]methanesulfonamide
CAS 833430-19-6C24H25N3O5S2
N-(3-(1-((4-Chlorophenyl)sulfonyl)-5-(2-fluorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C22H19ClFN3O4S2, CAS 833435-08-8
N-(3-(1-((4-Chlorophenyl)sulfonyl)-5-(2-fluorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 833435-08-8C22H19ClFN3O4S2
N-(4-(1-((4-Fluorophenyl)sulfonyl)-5-(3-nitrophenyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C23H21FN4O6S2, CAS 833437-69-7
N-(4-(1-((4-Fluorophenyl)sulfonyl)-5-(3-nitrophenyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 833437-69-7C23H21FN4O6S2
N-(3-(1-((4-Fluorophenyl)sulfonyl)-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C22H20FN3O4S2, CAS 833438-56-5
N-(3-(1-((4-Fluorophenyl)sulfonyl)-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 833438-56-5C22H20FN3O4S2
N-(3-(1-((4-Methoxyphenyl)sulfonyl)-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C23H23N3O5S2, CAS 833442-91-4
N-(3-(1-((4-Methoxyphenyl)sulfonyl)-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 833442-91-4C23H23N3O5S2
N-(4-(1-((4-Chlorophenyl)sulfonyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C23H21ClFN3O4S2, CAS 833443-73-5
N-(4-(1-((4-Chlorophenyl)sulfonyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 833443-73-5C23H21ClFN3O4S2
N-(3-(1-((4-Chlorophenyl)sulfonyl)-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C23H22ClN3O4S2, CAS 835893-24-8
N-(3-(1-((4-Chlorophenyl)sulfonyl)-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 835893-24-8C23H22ClN3O4S2
N-(4-(1-((4-Fluorophenyl)sulfonyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C24H24FN3O5S2, CAS 838381-07-0
N-(4-(1-((4-Fluorophenyl)sulfonyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 838381-07-0C24H24FN3O5S2
N-(4-(1-((4-Chlorophenyl)sulfonyl)-5-(o-tolyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C23H22ClN3O4S2, CAS 838395-33-8
N-(4-(1-((4-Chlorophenyl)sulfonyl)-5-(o-tolyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 838395-33-8C23H22ClN3O4S2
N-(4-(5-(2-Fluorophenyl)-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C22H20FN3O4S2, CAS 838811-63-5
N-(4-(5-(2-Fluorophenyl)-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 838811-63-5C22H20FN3O4S2
N-(4-(5-(3-Fluorophenyl)-1-tosyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C23H22FN3O4S2, CAS 838849-72-2
N-(4-(5-(3-Fluorophenyl)-1-tosyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 838849-72-2C23H22FN3O4S2
N-(4-(1-((4-Fluorophenyl)sulfonyl)-5-(o-tolyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C24H24FN3O4S2, CAS 838849-88-0
N-(4-(1-((4-Fluorophenyl)sulfonyl)-5-(o-tolyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 838849-88-0C24H24FN3O4S2
3,5-Bis(4-methoxyphenyl)-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazole chemical structure, C23H22N2O4S, CAS 76973-47-2
3,5-Bis(4-methoxyphenyl)-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazole
CAS 76973-47-2C23H22N2O4S