Murcko scaffold
10-[(Piperidin-3-yl)methyl]-10H-phenothiazine scaffold
20 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 21
- Chemicals
- 20
- With full pages
- 3
Scaffold SMILES
c1ccc2c(c1)Sc1ccccc1N2CC1CCCNC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 20 of 20 chemicals
Pecazine
CAS 60-89-9C19H22N2S
10H-Phenothiazine, 10-((1-methyl-3-piperidinyl)methyl)-, hydrochloride (1:1)
CAS 2975-36-2C19H23ClN2S
Phenothiazine, 10-((N-butyl-3-piperidyl)methyl)-
CAS 63833-97-6C22H28N2S
Phenothiazine, 10-((N-ethyl-3-piperidyl)methyl)-
CAS 63834-09-3C20H24N2S
Phenothiazine, 10-((N-isopropyl-3-piperidyl)methyl)-
CAS 63834-10-6C21H26N2S
Phenothiazine, 10-((N-propyl-3-piperidyl)methyl)-
CAS 63834-17-3C21H26N2S
Phenothiazine, 2-chloro-10-(1-methyl-3-piperidylmethyl)-
CAS 3689-38-1C19H21ClN2S
Mepazine acetate
CAS 24360-97-2C21H26N2O2S
Phenothiazine, 3-methoxy-10-((1-methyl-3-piperidyl)methyl)-
CAS 101976-48-1C20H24N2OS
![10-[[(3R)-1-Methylpiperidin-3-yl]methyl]phenothiazine chemical structure, C19H22N2S, CAS 1460240-93-0](/s/CBHCDHNUZWWAPP-OAHLLOKOSA-N.svg)
10-[[(3R)-1-Methylpiperidin-3-yl]methyl]phenothiazine
CAS 1460240-93-0C19H22N2S
Mepazine, (S)-
CAS 1460240-94-1C19H22N2S
![10-[(1,3-Dimethyl-3-piperidyl)methyl]phenothiazine chemical structure, C20H25ClN2S, CAS 66230-33-9](/s/MYUWOJBSKBWECL-UHFFFAOYSA-N.svg)
10-[(1,3-Dimethyl-3-piperidyl)methyl]phenothiazine
CAS 66230-33-9C20H25ClN2S
Mepazine hydrochloride monohydrate
CAS 6146-88-9C19H25ClN2OS
![10-[(Piperidin-3-yl)methyl]-10H-phenothiazine chemical structure, C18H20N2S, CAS 89929-25-9](/s/LWYCSDJJCQEQAF-UHFFFAOYSA-N.svg)
10-[(Piperidin-3-yl)methyl]-10H-phenothiazine
CAS 89929-25-9C18H20N2S
![10-[(Piperidin-3-yl)methyl]-10H-phenothiazin-1-ol chemical structure, C18H20N2OS, CAS 89907-40-4](/s/CUHYRYQKHKZJMY-UHFFFAOYSA-N.svg)
10-[(Piperidin-3-yl)methyl]-10H-phenothiazin-1-ol
CAS 89907-40-4C18H20N2OS
![10-[(1-Methylpiperidin-3-yl)methyl]-10H-phenothiazin-1-ol chemical structure, C19H22N2OS, CAS 89907-42-6](/s/NKTFCQQTFZFARJ-UHFFFAOYSA-N.svg)
10-[(1-Methylpiperidin-3-yl)methyl]-10H-phenothiazin-1-ol
CAS 89907-42-6C19H22N2OS
Mepazine hydrochloride, (R)-
CAS 1460240-95-2C19H23ClN2S
Mepazine hydrochloride, (S)-
CAS 1460240-96-3C19H23ClN2S
10-(3-Piperidinylmethyl)-10H-phenothiazine hydrochloride
CAS 2206264-84-6C18H21ClN2S
3-(10H-Phenothiazin-10-ylmethyl)-1-piperidinecarboximidamide hydrochloride
CAS 2203070-83-9C19H23ClN4S
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(Nc2c3ccccc3nc3ccccc23)cc180 chemicals
O=C1c2ccccc2C(=Cc2ccccc2)c2ccccc2110 chemicals
O=C(c1ccccc1)N1c2ccccc2Sc2ccccc214 chemicals
c1ccc2c(c1)Sc1ccccc1C2CC1CCCNC14 chemicals
O=C(N1CCCCC1)N1c2ccccc2Sc2ccccc214 chemicals
c1ccc(Cc2c3ccccc3cc3ccccc23)cc13 chemicals
O=C(C1c2ccccc2Oc2ccccc21)N1CCCCC13 chemicals
O=c1c2ccccc2n(Cc2ccccc2)c2ccccc122 chemicals
c1ccc(Oc2c3ccccc3nc3ccccc23)cc12 chemicals
O=c1cccc2n(CC3=CCCCC3)c3ccccc3nc1-22 chemicals
O=C(N1CCOCC1)N1c2ccccc2Sc2ccccc212 chemicals
c1ccc2c(CN3CCNCC3)c3ccccc3cc2c12 chemicals