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Murcko scaffold

Ring system with 4 rings and 23 atoms

4 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
4
With full pages
2
Scaffold SMILES

c1cncc(-c2nccc(N3CCc4ccccc4CC3)n2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cncc(-c2nccc(N3CCc4ccccc4CC3)n2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

3-[[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)-4-pyrimidinyl]amino]propanoic acid chemical structure, C22H23N5O2, CAS 1394854-52-4
3-[[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)-4-pyrimidinyl]amino]propanoic acid
CAS 1394854-52-4C22H23N5O2
Ethyl 3-[[2-pyridin-3-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate chemical structure, C24H27N5O2, CAS 1394854-51-3
Ethyl 3-[[2-pyridin-3-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate
CAS 1394854-51-3C24H27N5O2
GSK J5 HCl chemical structure, C24H28ClN5O2, CAS 1797983-32-4
GSK J5 HCl
CAS 1797983-32-4C24H28ClN5O2
GSK-J2 sodium salt chemical structure, C22H23N5NaO2, CAS 2108665-15-0
GSK-J2 sodium salt
CAS 2108665-15-0C22H23N5NaO2