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Murcko scaffold

1-Phenylpyrimidine-2,4,6(1H,3H,5H)-trione scaffold

72 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 15
Chemicals: 72
With full pages: 27

Scaffold SMILES

O=C1CC(=O)N(c2ccccc2)C(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 1-Phenylpyrimidine-2,4,6(1H,3H,5H)-trione page

Murcko scaffold O=C1CC(=O)N(c2ccccc2)C(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 72 chemicals

Phetharbital chemical structure, C14H16N2O3, CAS 357-67-5

CAS 357-67-5C₁₄H₁₆N₂O₃

Barbituric acid, 5-allyl-1-phenyl- chemical structure, C13H12N2O3, CAS 786-56-1

Barbituric acid, 5-allyl-1-phenyl-

CAS 786-56-1C₁₃H₁₂N₂O₃

5-Allyl-5-(beta-hydroxypropyl)-N-phenylbarbituric acid chemical structure, C16H18N2O4, CAS 14305-83-0

5-Allyl-5-(beta-hydroxypropyl)-N-phenylbarbituric acid

CAS 14305-83-0C₁₆H₁₈N₂O₄

Barbituric acid, 5-butyl-1-phenyl- chemical structure, C14H16N2O3, CAS 18160-14-0

Barbituric acid, 5-butyl-1-phenyl-

CAS 18160-14-0C₁₄H₁₆N₂O₃

1-4-Dimethylaminophenyl-5-allyl-5-(beta-hydroxypropyl)barbituric acid chemical structure, C18H23N3O4, CAS 33074-61-2

1-4-Dimethylaminophenyl-5-allyl-5-(beta-hydroxypropyl)barbituric acid

CAS 33074-61-2C₁₈H₂₃N₃O₄

Barbituric acid, 1-(p-chlorophenyl)-5,5-diethyl- chemical structure, C14H15ClN2O3, CAS 66940-50-9

Barbituric acid, 1-(p-chlorophenyl)-5,5-diethyl-

CAS 66940-50-9C₁₄H₁₅ClN₂O₃

Barbituric acid, 5,5-diethyl-1-(p-ethoxyphenyl)- chemical structure, C16H20N2O4, CAS 66940-84-9

Barbituric acid, 5,5-diethyl-1-(p-ethoxyphenyl)-

CAS 66940-84-9C₁₆H₂₀N₂O₄

Barbituric acid, 5,5-diethyl-1-(p-methoxyphenyl)- chemical structure, C15H18N2O4, CAS 66940-92-9

Barbituric acid, 5,5-diethyl-1-(p-methoxyphenyl)-

CAS 66940-92-9C₁₅H₁₈N₂O₄

Barbituric acid, 1-(p-bromophenyl)-5,5-diethyl- chemical structure, C14H15BrN2O3, CAS 66942-13-0

Barbituric acid, 1-(p-bromophenyl)-5,5-diethyl-

CAS 66942-13-0C₁₄H₁₅BrN₂O₃

Barbituric acid, 5-ethyl-5-isobutyl-1-phenyl- chemical structure, C16H20N2O3, CAS 66968-50-1

Barbituric acid, 5-ethyl-5-isobutyl-1-phenyl-

CAS 66968-50-1C₁₆H₂₀N₂O₃

Barbituric acid, 5-ethyl-5-isopentyl-1-phenyl- chemical structure, C17H22N2O3, CAS 66968-55-6

Barbituric acid, 5-ethyl-5-isopentyl-1-phenyl-

CAS 66968-55-6C₁₇H₂₂N₂O₃

5-Butyl-5-ethyl-6-hydroxy-3-phenylpyrimidine-2,4(3H,5H)-dione chemical structure, C16H20N2O3, CAS 67050-28-6

5-Butyl-5-ethyl-6-hydroxy-3-phenylpyrimidine-2,4(3H,5H)-dione

CAS 67050-28-6C₁₆H₂₀N₂O₃

5-Ethyl-6-hydroxy-3-phenyl-5-propylpyrimidine-2,4(3H,5H)-dione chemical structure, C15H18N2O3, CAS 67114-24-3

5-Ethyl-6-hydroxy-3-phenyl-5-propylpyrimidine-2,4(3H,5H)-dione

CAS 67114-24-3C₁₅H₁₈N₂O₃

Barbituric acid, 5,5-diethyl-1-(p-tolyl)- chemical structure, C15H18N2O3, CAS 69766-58-1

Barbituric acid, 5,5-diethyl-1-(p-tolyl)-

CAS 69766-58-1C₁₅H₁₈N₂O₃

5-(Dimethylamino)-3-(4-ethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione chemical structure, C14H17N3O4, CAS 92440-69-2

5-(Dimethylamino)-3-(4-ethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione

CAS 92440-69-2C₁₄H₁₇N₃O₄

Barbituric acid, 5-(diethylamino)-1-(p-ethoxyphenyl)- chemical structure, C16H21N3O4, CAS 93150-57-3

Barbituric acid, 5-(diethylamino)-1-(p-ethoxyphenyl)-

CAS 93150-57-3C₁₆H₂₁N₃O₄

2,4,6(1H,3H,5H)-Pyrimidinetrione, 1-(3-chlorophenyl)-3-methyl- chemical structure, C11H9ClN2O3, CAS 1983-34-2

2,4,6(1H,3H,5H)-Pyrimidinetrione, 1-(3-chlorophenyl)-3-methyl-

CAS 1983-34-2C₁₁H₉ClN₂O₃

5-Ethyl-1-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione chemical structure, C12H12N2O3, CAS 5419-00-1

5-Ethyl-1-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione

CAS 5419-00-1C₁₂H₁₂N₂O₃

Barbituric acid, 5-(3-hydroxybutyl)-1-phenyl- chemical structure, C14H16N2O4, CAS 17148-45-7

Barbituric acid, 5-(3-hydroxybutyl)-1-phenyl-

CAS 17148-45-7C₁₄H₁₆N₂O₄

Barbituric acid, 5-methyl-1-phenyl- chemical structure, C11H10N2O3, CAS 19011-60-0

Barbituric acid, 5-methyl-1-phenyl-

CAS 19011-60-0C₁₁H₁₀N₂O₃

Barbituric acid, 1-phenyl-5-propyl- chemical structure, C13H14N2O3, CAS 19011-62-2

Barbituric acid, 1-phenyl-5-propyl-

CAS 19011-62-2C₁₃H₁₄N₂O₃

6-Hydroxy-5-(3-oxobutyl)-3-phenylpyrimidine-2,4(3H,5H)-dione chemical structure, C14H14N2O4, CAS 20942-22-7

6-Hydroxy-5-(3-oxobutyl)-3-phenylpyrimidine-2,4(3H,5H)-dione

CAS 20942-22-7C₁₄H₁₄N₂O₄

Barbituric acid, 5-(4-hydroxybutyl)-1-phenyl- chemical structure, C14H16N2O4, CAS 21367-95-3

Barbituric acid, 5-(4-hydroxybutyl)-1-phenyl-

CAS 21367-95-3C₁₄H₁₆N₂O₄

1-Phenylpyrimidine-2,4,6(1H,3H,5H)-trione chemical structure, C10H8N2O3, CAS 15018-50-5

1-Phenylpyrimidine-2,4,6(1H,3H,5H)-trione

CAS 15018-50-5C₁₀H₈N₂O₃