Murcko scaffold
Dibenzyl ether scaffold
228 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 15
- Chemicals
- 228
- With full pages
- 4
Scaffold SMILES
c1ccc(COCc2ccccc2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 228 chemicals
1,1'-((Oxybis(methylene))bis(5-chloro-2-hydroxy-3,1-phenylene))diethanone
CAS 50525-73-0C18H16Cl2O5
![4,4'-[Oxybis(methylene)]bisbenzoic acid chemical structure, C16H14O5, CAS 55255-64-6](/s/VBMVMQFIJODWIZ-UHFFFAOYSA-N.svg)
4,4'-[Oxybis(methylene)]bisbenzoic acid
CAS 55255-64-6C16H14O5
2-Benzyloxymethyl-5-chlorobenzaldehyde
CAS 104454-08-2C15H13ClO2
![3-[(Benzyloxy)methyl]aniline chemical structure, C14H15NO, CAS 117401-77-1](/s/YNGZKYBHLZBSRH-UHFFFAOYSA-N.svg)
3-[(Benzyloxy)methyl]aniline
CAS 117401-77-1C14H15NO
![N-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-formamide chemical structure, C16H13Cl4NO2, CAS 911805-54-4](/s/FNCVZCLFBSGWSC-UHFFFAOYSA-N.svg)
N-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-formamide
CAS 911805-54-4C16H13Cl4NO2
![1,1'-[Oxybis(methylene)]bis(pentabromobenzene) chemical structure, C14H4Br10O, CAS 497107-13-8](/s/GYYJNXRFVBJOEW-UHFFFAOYSA-N.svg)
1,1'-[Oxybis(methylene)]bis(pentabromobenzene)
CAS 497107-13-8C14H4Br10O
![1,1'-[Oxybis(methylene)]bis(3,4,5-trimethoxybenzene) chemical structure, C20H26O7, CAS 68299-87-6](/s/RNIYRJCVGUZXSH-UHFFFAOYSA-N.svg)
1,1'-[Oxybis(methylene)]bis(3,4,5-trimethoxybenzene)
CAS 68299-87-6C20H26O7
![1,1'-[Oxybis(methylene)]bis(2-methylbenzene) chemical structure, C16H18O, CAS 51555-88-5](/s/LRKLFZPYIDPEHV-UHFFFAOYSA-N.svg)
1,1'-[Oxybis(methylene)]bis(2-methylbenzene)
CAS 51555-88-5C16H18O
DI-(4-Vinylbenzyl)ether
CAS 115444-35-4C18H18O
(4-((Benzyloxy)methyl)phenyl)methanamine
CAS 953899-70-2C15H17NO
![{2-[(Benzyloxy)methyl]phenyl}methanamine chemical structure, C15H17NO, CAS 954577-97-0](/s/QSIRNNPYPDJFBS-UHFFFAOYSA-N.svg)
{2-[(Benzyloxy)methyl]phenyl}methanamine
CAS 954577-97-0C15H17NO
![{3-[(Benzyloxy)methyl]phenyl}methanamine chemical structure, C15H17NO, CAS 954582-86-6](/s/YSCFZTBGWPBNLY-UHFFFAOYSA-N.svg)
{3-[(Benzyloxy)methyl]phenyl}methanamine
CAS 954582-86-6C15H17NO
![2-[(Benzyloxy)methyl]aniline chemical structure, C14H15NO, CAS 1016498-66-0](/s/FEZQBNAKAKTQFJ-UHFFFAOYSA-N.svg)
2-[(Benzyloxy)methyl]aniline
CAS 1016498-66-0C14H15NO
![1,1'-[Oxybis(methylene)]bis[4-(trifluoromethyl)benzene] chemical structure, C16H12F6O, CAS 162404-64-0](/s/LDGRTPLGYXKHRQ-UHFFFAOYSA-N.svg)
1,1'-[Oxybis(methylene)]bis[4-(trifluoromethyl)benzene]
CAS 162404-64-0C16H12F6O
![{3-[(Benzyloxy)methyl]-4-methoxyphenyl}methanamine chemical structure, C16H19NO2, CAS 897094-84-7](/s/MYEPIBMRMZQPDH-UHFFFAOYSA-N.svg)
{3-[(Benzyloxy)methyl]-4-methoxyphenyl}methanamine
CAS 897094-84-7C16H19NO2
![2-[(1-Phenylethoxy)methyl]aniline chemical structure, C15H17NO, CAS 1016513-16-8](/s/XRMAQZGKUXPPSS-UHFFFAOYSA-N.svg)
2-[(1-Phenylethoxy)methyl]aniline
CAS 1016513-16-8C15H17NO
Benzeneethanamine,3-chloro-b-(phenylmethoxy)-
CAS 90470-30-7C15H16ClNO
Bis(3,5-dimethylbenzyl)ether
CAS 27129-88-0C18H22O
![4-[(Phenylmethoxy)methyl]benzaldehyde chemical structure, C15H14O2, CAS 216384-72-4](/s/WDOACPFJZBNRPJ-UHFFFAOYSA-N.svg)
4-[(Phenylmethoxy)methyl]benzaldehyde
CAS 216384-72-4C15H14O2
4,4'-(Oxybis(methylene))dianiline
CAS 96727-43-4C14H16N2O
![1,1'-[Oxybis(methylene-4,1-phenylene)]di(ethan-1-one) chemical structure, C18H18O3, CAS 142495-24-7](/s/PFMVPBWNSIMQMI-UHFFFAOYSA-N.svg)
1,1'-[Oxybis(methylene-4,1-phenylene)]di(ethan-1-one)
CAS 142495-24-7C18H18O3
![4,4'-[Oxybis(methylene)]bis[2-methoxyphenol] chemical structure, C16H18O5, CAS 2880-61-7](/s/LSKFRYMLGSVAPL-UHFFFAOYSA-N.svg)
4,4'-[Oxybis(methylene)]bis[2-methoxyphenol]
CAS 2880-61-7C16H18O5
(4-((Benzyloxy)methyl)phenyl)boronic acid
CAS 163680-70-4C14H15BO3
Bis(2,3,6-tribromo-4,5-dihydroxybenzyl) ether
CAS 52897-70-8C14H8Br6O5
- 4-[(Phenylmethoxy)methyl]benzoic acid22714-44-9C15H14O3
- 3-[(Phenylmethoxy)methyl]benzoic acid1016891-82-9C15H14O3
- 2-[[(3-Methoxyphenyl)methoxy]methyl]benzenemethanamine1016819-91-2C16H19NO2
- 3-((Benzyloxy)methyl)benzonitrile1016847-73-6C15H13NO
- Terrestrol B1005338-77-1C14H13ClO5
- Terrestrol C1005338-78-2C14H14O5
- 3-{[(4-Methoxyphenyl)methoxy]methyl}aniline1021042-81-8C15H17NO2
- 2-((Benzyloxy)methyl)benzoic acid119367-89-4C15H14O3
- 2-(2-Chloro-benzyloxymethyl)-benzoic acid1154953-86-2C15H13ClO3
- Bis-(3-bromo-2-fluorobenzyl)ether1186195-12-9C14H10Br2F2O
- 2-(2-Methyl-benzyloxymethyl)-benzoic acid353747-88-3C16H16O3
- 2-(2-Methyl-benzyloxymethyl)-benzoic acid methyl ester1171923-18-4C17H18O3
- 2-(2-Chloro-benzyloxymethyl)-benzoic acid methyl ester1171923-29-7C16H15ClO3
- 2-(2-Chloro-benzyloxymethyl)-6-methoxy-benzoic acid1171923-40-2C16H15ClO4
- 2-Methoxy-N-methyl-6-(2-methyl-benzyloxymethyl)-benzamide1171923-43-5C18H21NO3
- 2-Methoxy-6-(2-methyl-benzyloxymethyl)-benzoic acid1171923-46-8C17H18O4
- 2-Methoxy-6-(2-methyl-benzyloxymethyl)-benzoic acid ethyl ester1171923-49-1C19H22O4
- 2-(2,4-Dimethyl-benzyloxymethyl)-6-methoxy-benzoic acid1171923-51-5C18H20O4
- 2-(4-Chloro-benzyloxymethyl)-6-methoxy-benzoic acid1171923-53-7C16H15ClO4
- 2-(3,4-Dichloro-benzyloxymethyl)-6-methoxy-benzoic acid1171923-58-2C16H14Cl2O4
- 2-(2,4-Dichloro-benzyloxymethyl)-6-methoxy-benzoic acid1171923-61-7C16H14Cl2O4
- 2-(5-tert-Butyl-2-methyl-benzyloxymethyl)-6-methoxy-benzoic acid1171923-64-0C21H26O4
- 2-(3,4-Dichloro-benzyloxymethyl)-6-methoxy-benzoic acid methyl ester1171923-68-4C17H16Cl2O4
- 2-(2-Chloro-benzyloxymethyl)-6-methoxy-benzoic acid methyl ester1171923-79-7C17H17ClO4
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(C=Cc1ccccc1)c1ccccc193 chemicals
O=C(Nc1ccccc1)Nc1ccccc136 chemicals
O=C(CCc1ccccc1)c1ccccc136 chemicals
c1ccc(CNCc2ccccc2)cc123 chemicals
O=C(NCc1ccccc1)c1ccccc120 chemicalsOc1ccccc1](/scaffold/OGBPILLJZSJJRC-UHFFFAOYSA-N/structure.svg)
O=[PH](Oc1ccccc1)Oc1ccccc119 chemicals
c1ccc(CCOc2ccccc2)cc118 chemicals
O=C(CC(=O)c1ccccc1)c1ccccc113 chemicals
O=C(OCc1ccccc1)c1ccccc113 chemicals
O=C(OCc1ccccc1)N1CCCCC113 chemicals
O=C(Cc1ccccc1)Nc1ccccc111 chemicals
c1ccc(CCCN2CCOCC2)cc110 chemicals