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Murcko scaffold

1-[(6-Phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl)methyl]-1H-benzimidazole scaffold

15 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
24
Chemicals
15
With full pages
3
Scaffold SMILES

c1ccc(-c2nn3c(Cn4cnc5ccccc54)nnc3s2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-[(6-Phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl)methyl]-1H-benzimidazole page
Murcko scaffold c1ccc(-c2nn3c(Cn4cnc5ccccc54)nnc3s2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

3-(Benzimidazol-1-ylmethyl)-6-(2-chlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C17H11ClN6S, CAS 825605-05-8
3-(Benzimidazol-1-ylmethyl)-6-(2-chlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 825605-05-8C17H11ClN6S
3-(Benzimidazol-1-ylmethyl)-6-(3-chlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C17H11ClN6S, CAS 791805-94-2
3-(Benzimidazol-1-ylmethyl)-6-(3-chlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 791805-94-2C17H11ClN6S
3-(Benzimidazol-1-ylmethyl)-6-(2,4-dichlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C17H10Cl2N6S, CAS 825605-09-2
3-(Benzimidazol-1-ylmethyl)-6-(2,4-dichlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 825605-09-2C17H10Cl2N6S
1-[(6-Phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl)methyl]-1H-benzimidazole chemical structure, C17H12N6S, CAS 791806-34-3
1-[(6-Phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl)methyl]-1H-benzimidazole
CAS 791806-34-3C17H12N6S
3-(Benzimidazol-1-ylmethyl)-6-(3-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C18H14N6OS, CAS 791805-96-4
3-(Benzimidazol-1-ylmethyl)-6-(3-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 791805-96-4C18H14N6OS
3-(Benzimidazol-1-ylmethyl)-6-(4-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C18H14N6OS, CAS 791805-97-5
3-(Benzimidazol-1-ylmethyl)-6-(4-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 791805-97-5C18H14N6OS
3-(Benzimidazol-1-ylmethyl)-6-(3,4-dimethoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C19H16N6O2S, CAS 791805-98-6
3-(Benzimidazol-1-ylmethyl)-6-(3,4-dimethoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 791805-98-6C19H16N6O2S
3-(Benzimidazol-1-ylmethyl)-6-(4-tert-butylphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C21H20N6S, CAS 791805-91-9
3-(Benzimidazol-1-ylmethyl)-6-(4-tert-butylphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 791805-91-9C21H20N6S
3-(Benzimidazol-1-ylmethyl)-6-(2-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C18H14N6OS, CAS 825605-11-6
3-(Benzimidazol-1-ylmethyl)-6-(2-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 825605-11-6C18H14N6OS
1-{[6-(2,5-Dichlorophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]methyl}-1H-benzimidazole chemical structure, C17H10Cl2N6S, CAS 825605-10-5
1-{[6-(2,5-Dichlorophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]methyl}-1H-benzimidazole
CAS 825605-10-5C17H10Cl2N6S
3-(Benzimidazol-1-ylmethyl)-6-(4-methylphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C18H14N6S, CAS 876712-40-2
3-(Benzimidazol-1-ylmethyl)-6-(4-methylphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 876712-40-2C18H14N6S
3-(Benzimidazol-1-ylmethyl)-6-(3-fluorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C17H11FN6S, CAS 825605-08-1
3-(Benzimidazol-1-ylmethyl)-6-(3-fluorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 825605-08-1C17H11FN6S
3-(Benzimidazol-1-ylmethyl)-6-(4-fluorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C17H11FN6S, CAS 791805-95-3
3-(Benzimidazol-1-ylmethyl)-6-(4-fluorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 791805-95-3C17H11FN6S
3-(Benzimidazol-1-ylmethyl)-6-(4-chlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C17H11ClN6S, CAS 825605-06-9
3-(Benzimidazol-1-ylmethyl)-6-(4-chlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 825605-06-9C17H11ClN6S
1-{[6-(3-Bromo-4-fluorophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]methyl}-2-methyl-1H-benzimidazole chemical structure, C18H12BrFN6S, CAS 929816-68-2
1-{[6-(3-Bromo-4-fluorophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]methyl}-2-methyl-1H-benzimidazole
CAS 929816-68-2C18H12BrFN6S