Murcko scaffold
Ring system with 4 rings and 31 atoms
18 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 31
- Chemicals
- 18
- With full pages
- 5
Scaffold SMILES
O=C(COc1ccccc1)Nc1ccc(N2CCN(C(=O)c3ccccc3)CC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 18 of 18 chemicals
![N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(2-chlorophenoxy)acetamide chemical structure, C25H24ClN3O3, CAS 426220-87-3](/s/HUCFCNNWKPUVBP-UHFFFAOYSA-N.svg)
N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(2-chlorophenoxy)acetamide
CAS 426220-87-3C25H24ClN3O3
![N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(4-tert-butylphenoxy)acetamide chemical structure, C29H33N3O3, CAS 428469-10-7](/s/HWXRWNKOHRYZHS-UHFFFAOYSA-N.svg)
N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(4-tert-butylphenoxy)acetamide
CAS 428469-10-7C29H33N3O3
![N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(4-bromophenoxy)acetamide chemical structure, C25H24BrN3O3, CAS 428497-56-7](/s/XXZDAWRBWIVEIR-UHFFFAOYSA-N.svg)
N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(4-bromophenoxy)acetamide
CAS 428497-56-7C25H24BrN3O3
![N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(2,3-dimethylphenoxy)acetamide chemical structure, C27H29N3O3, CAS 832682-40-3](/s/RRFVCMMVXLYIDV-UHFFFAOYSA-N.svg)
N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(2,3-dimethylphenoxy)acetamide
CAS 832682-40-3C27H29N3O3
![N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(2-bromo-4,6-dimethylphenoxy)acetamide chemical structure, C27H28BrN3O3, CAS 662153-38-0](/s/KVOZALULSYNUDV-UHFFFAOYSA-N.svg)
N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(2-bromo-4,6-dimethylphenoxy)acetamide
CAS 662153-38-0C27H28BrN3O3
![2-(4-Chloro-3,5-dimethylphenoxy)-N-{4-[4-(phenylcarbonyl)piperazin-1-yl]phenyl}acetamide chemical structure, C27H28ClN3O3, CAS 428466-09-5](/s/JEZVBIWEJKURFX-UHFFFAOYSA-N.svg)
2-(4-Chloro-3,5-dimethylphenoxy)-N-{4-[4-(phenylcarbonyl)piperazin-1-yl]phenyl}acetamide
CAS 428466-09-5C27H28ClN3O3
![N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(4-methoxyphenoxy)acetamide chemical structure, C26H27N3O4, CAS 426220-40-8](/s/DBAUVEXOPDBPBZ-UHFFFAOYSA-N.svg)
N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(4-methoxyphenoxy)acetamide
CAS 426220-40-8C26H27N3O4
![N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(4-nitrophenoxy)acetamide chemical structure, C25H24N4O5, CAS 428486-22-0](/s/VGPOVARWIZKPCY-UHFFFAOYSA-N.svg)
N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(4-nitrophenoxy)acetamide
CAS 428486-22-0C25H24N4O5
![N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(2,4-dichlorophenoxy)acetamide chemical structure, C25H23Cl2N3O3, CAS 428496-11-1](/s/KXPJQAFMDXEWPN-UHFFFAOYSA-N.svg)
N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(2,4-dichlorophenoxy)acetamide
CAS 428496-11-1C25H23Cl2N3O3
![N-[4-[4-(4-Methylbenzoyl)piperazin-1-yl]phenyl]-2-(4-nitrophenoxy)acetamide chemical structure, C26H26N4O5, CAS 642419-05-4](/s/FSOVHGFQOAOJLP-UHFFFAOYSA-N.svg)
N-[4-[4-(4-Methylbenzoyl)piperazin-1-yl]phenyl]-2-(4-nitrophenoxy)acetamide
CAS 642419-05-4C26H26N4O5
![2-(2-Chlorophenoxy)-N-[4-[4-(4-methylbenzoyl)piperazin-1-yl]phenyl]acetamide chemical structure, C26H26ClN3O3, CAS 642419-13-4](/s/GOKJEFBYSJADTN-UHFFFAOYSA-N.svg)
2-(2-Chlorophenoxy)-N-[4-[4-(4-methylbenzoyl)piperazin-1-yl]phenyl]acetamide
CAS 642419-13-4C26H26ClN3O3
![N-[4-[4-(2-Methylbenzoyl)piperazin-1-yl]phenyl]-2-(2-methylphenoxy)acetamide chemical structure, C27H29N3O3, CAS 642427-04-1](/s/NYIVUSNNMCOXPJ-UHFFFAOYSA-N.svg)
N-[4-[4-(2-Methylbenzoyl)piperazin-1-yl]phenyl]-2-(2-methylphenoxy)acetamide
CAS 642427-04-1C27H29N3O3
![2-(2,3-Dimethylphenoxy)-N-[4-[4-(4-methylbenzoyl)piperazin-1-yl]phenyl]acetamide chemical structure, C28H31N3O3, CAS 642419-37-2](/s/VUPMLYVDELMVGH-UHFFFAOYSA-N.svg)
2-(2,3-Dimethylphenoxy)-N-[4-[4-(4-methylbenzoyl)piperazin-1-yl]phenyl]acetamide
CAS 642419-37-2C28H31N3O3
![2-(4-Chlorophenoxy)-N-[4-[4-(2-methylbenzoyl)piperazin-1-yl]phenyl]acetamide chemical structure, C26H26ClN3O3, CAS 642427-02-9](/s/LOEPXYVPWJHHMH-UHFFFAOYSA-N.svg)
2-(4-Chlorophenoxy)-N-[4-[4-(2-methylbenzoyl)piperazin-1-yl]phenyl]acetamide
CAS 642427-02-9C26H26ClN3O3
![N-[4-[4-(4-Methylbenzoyl)piperazin-1-yl]phenyl]-2-(2-methylphenoxy)acetamide chemical structure, C27H29N3O3, CAS 689748-96-7](/s/XIZBVAXPDNAUGL-UHFFFAOYSA-N.svg)
N-[4-[4-(4-Methylbenzoyl)piperazin-1-yl]phenyl]-2-(2-methylphenoxy)acetamide
CAS 689748-96-7C27H29N3O3
![N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(4-propan-2-ylphenoxy)acetamide chemical structure, C28H31N3O3, CAS 832679-96-6](/s/IPLDKTBTTKQCMF-UHFFFAOYSA-N.svg)
N-[4-(4-Benzoylpiperazin-1-yl)phenyl]-2-(4-propan-2-ylphenoxy)acetamide
CAS 832679-96-6C28H31N3O3
![2-(3,4-Dimethylphenoxy)-N-[4-[4-(2-methylbenzoyl)piperazin-1-yl]phenyl]acetamide chemical structure, C28H31N3O3, CAS 689743-21-3](/s/QVRSYPMPRXRHGC-UHFFFAOYSA-N.svg)
2-(3,4-Dimethylphenoxy)-N-[4-[4-(2-methylbenzoyl)piperazin-1-yl]phenyl]acetamide
CAS 689743-21-3C28H31N3O3
![N-[4-(4-Benzoylpiperazin-1-yl)-3-chlorophenyl]-2-(4-methoxyphenoxy)acetamide chemical structure, C26H26ClN3O4, CAS 839692-80-7](/s/XNPJVVJWSJESDM-UHFFFAOYSA-N.svg)
N-[4-(4-Benzoylpiperazin-1-yl)-3-chlorophenyl]-2-(4-methoxyphenoxy)acetamide
CAS 839692-80-7C26H26ClN3O4
Related scaffolds
Same ring framework with different atoms or bond orders
