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Murcko scaffold

Ring system with 4 rings and 32 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
32
Chemicals
9
With full pages
9
Scaffold SMILES

O=C(CNC(=O)c1ccccc1)NN=Cc1cn(-c2ccccc2)nc1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNC(=O)c1ccccc1)NN=Cc1cn(-c2ccccc2)nc1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

N-(2-(2-((3-(4-Methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)-4-propoxybenzamide chemical structure, C29H29N5O3, CAS 881683-56-3
N-(2-(2-((3-(4-Methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)-4-propoxybenzamide
CAS 881683-56-3C29H29N5O3
4-Methoxy-N-(2-(2-((3-(4-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C27H25N5O3, CAS 881683-67-6
4-Methoxy-N-(2-(2-((3-(4-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)benzamide
CAS 881683-67-6C27H25N5O3
N-(2-(2-((3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)-4-methoxybenzamide chemical structure, C26H22FN5O3, CAS 881839-98-1
N-(2-(2-((3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)-4-methoxybenzamide
CAS 881839-98-1C26H22FN5O3
N-(2-(2-((3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)-4-propoxybenzamide chemical structure, C28H26FN5O3, CAS 881840-06-8
N-(2-(2-((3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)-4-propoxybenzamide
CAS 881840-06-8C28H26FN5O3
4-Methyl-N-(2-(2-((3-(4-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C27H25N5O2, CAS 881840-10-4
4-Methyl-N-(2-(2-((3-(4-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)benzamide
CAS 881840-10-4C27H25N5O2
3,4-Dichloro-N-(2-(2-((3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C25H18Cl2FN5O2, CAS 881402-89-7
3,4-Dichloro-N-(2-(2-((3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)benzamide
CAS 881402-89-7C25H18Cl2FN5O2
3-Bromo-N-(2-(2-((3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C25H19BrFN5O2, CAS 881403-32-3
3-Bromo-N-(2-(2-((3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)benzamide
CAS 881403-32-3C25H19BrFN5O2
N-(2-(2-((3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)-3,4-dimethoxybenzamide chemical structure, C27H24FN5O4, CAS 881664-56-8
N-(2-(2-((3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)-3,4-dimethoxybenzamide
CAS 881664-56-8C27H24FN5O4
4-Fluoro-N-(2-(2-((3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C25H19F2N5O2, CAS 881664-87-5
4-Fluoro-N-(2-(2-((3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazino)-2-oxoethyl)benzamide
CAS 881664-87-5C25H19F2N5O2