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Murcko scaffold

Ring system with 4 rings and 29 atoms

26 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
29
Chemicals
26
With full pages
6
Scaffold SMILES

O=C(CN(c1ccccc1)S(=O)(=O)c1ccccc1)Nc1ccc2c(c1)OCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CN(c1ccccc1)S(=O)(=O)c1ccccc1)Nc1ccc2c(c1)OCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

N-(1,3-Benzodioxol-5-yl)-2-(3,5-dichloro-N-(4-methylphenyl)sulfonylanilino)acetamide chemical structure, C22H18Cl2N2O5S, CAS 361199-55-5
N-(1,3-Benzodioxol-5-yl)-2-(3,5-dichloro-N-(4-methylphenyl)sulfonylanilino)acetamide
CAS 361199-55-5C22H18Cl2N2O5S
N-(1,3-Benzodioxol-5-yl)-2-(3,4-dimethoxy-N-(4-methylphenyl)sulfonylanilino)acetamide chemical structure, C24H24N2O7S, CAS 496937-67-8
N-(1,3-Benzodioxol-5-yl)-2-(3,4-dimethoxy-N-(4-methylphenyl)sulfonylanilino)acetamide
CAS 496937-67-8C24H24N2O7S
N-(1,3-Benzodioxol-5-yl)-2-(N-(4-methoxyphenyl)sulfonylanilino)acetamide chemical structure, C22H20N2O6S, CAS 428446-52-0
N-(1,3-Benzodioxol-5-yl)-2-(N-(4-methoxyphenyl)sulfonylanilino)acetamide
CAS 428446-52-0C22H20N2O6S
N-(1,3-Benzodioxol-5-yl)-2-(2-methyl-N-(4-methylphenyl)sulfonylanilino)acetamide chemical structure, C23H22N2O5S, CAS 335211-29-5
N-(1,3-Benzodioxol-5-yl)-2-(2-methyl-N-(4-methylphenyl)sulfonylanilino)acetamide
CAS 335211-29-5C23H22N2O5S
N-(1,3-Benzodioxol-5-yl)-2-(3,4-dimethyl-N-(4-methylphenyl)sulfonylanilino)acetamide chemical structure, C24H24N2O5S, CAS 425683-11-0
N-(1,3-Benzodioxol-5-yl)-2-(3,4-dimethyl-N-(4-methylphenyl)sulfonylanilino)acetamide
CAS 425683-11-0C24H24N2O5S
N-(1,3-Benzodioxol-5-yl)-2-{2,4-dimethyl[(4-methylphenyl)sulfonyl]anilino}acetamide chemical structure, C24H24N2O5S, CAS 6386-99-8
N-(1,3-Benzodioxol-5-yl)-2-{2,4-dimethyl[(4-methylphenyl)sulfonyl]anilino}acetamide
CAS 6386-99-8C24H24N2O5S
N-(1,3-Benzodioxol-5-yl)-2-[2,5-dimethyl(phenylsulfonyl)anilino]acetamide chemical structure, C23H22N2O5S, CAS 398520-86-0
N-(1,3-Benzodioxol-5-yl)-2-[2,5-dimethyl(phenylsulfonyl)anilino]acetamide
CAS 398520-86-0C23H22N2O5S
2-[N-(Benzenesulfonyl)-3-methylanilino]-N-(1,3-benzodioxol-5-yl)acetamide chemical structure, C22H20N2O5S, CAS 425666-54-2
2-[N-(Benzenesulfonyl)-3-methylanilino]-N-(1,3-benzodioxol-5-yl)acetamide
CAS 425666-54-2C22H20N2O5S
N-(1,3-Benzodioxol-5-yl)-2-(3-chloro-N-(4-methylphenyl)sulfonylanilino)acetamide chemical structure, C22H19ClN2O5S, CAS 367915-04-6
N-(1,3-Benzodioxol-5-yl)-2-(3-chloro-N-(4-methylphenyl)sulfonylanilino)acetamide
CAS 367915-04-6C22H19ClN2O5S
N-(1,3-Benzodioxol-5-yl)-2-{4-ethoxy[(4-methylphenyl)sulfonyl]anilino}acetamide chemical structure, C24H24N2O6S, CAS 333745-55-4
N-(1,3-Benzodioxol-5-yl)-2-{4-ethoxy[(4-methylphenyl)sulfonyl]anilino}acetamide
CAS 333745-55-4C24H24N2O6S
N-(1,3-Benzodioxol-5-yl)-2-[3-chloro(phenylsulfonyl)anilino]acetamide chemical structure, C21H17ClN2O5S, CAS 501913-28-6
N-(1,3-Benzodioxol-5-yl)-2-[3-chloro(phenylsulfonyl)anilino]acetamide
CAS 501913-28-6C21H17ClN2O5S
2-[N-(Benzenesulfonyl)-5-chloro-2-methoxyanilino]-N-(1,3-benzodioxol-5-yl)acetamide chemical structure, C22H19ClN2O6S, CAS 333745-53-2
2-[N-(Benzenesulfonyl)-5-chloro-2-methoxyanilino]-N-(1,3-benzodioxol-5-yl)acetamide
CAS 333745-53-2C22H19ClN2O6S
2-[N-(Benzenesulfonyl)-5-chloro-2-methylanilino]-N-(1,3-benzodioxol-5-yl)acetamide chemical structure, C22H19ClN2O5S, CAS 333745-97-4
2-[N-(Benzenesulfonyl)-5-chloro-2-methylanilino]-N-(1,3-benzodioxol-5-yl)acetamide
CAS 333745-97-4C22H19ClN2O5S
2-[N-(Benzenesulfonyl)-3-(trifluoromethyl)anilino]-N-(1,3-benzodioxol-5-yl)acetamide chemical structure, C22H17F3N2O5S, CAS 428487-07-4
2-[N-(Benzenesulfonyl)-3-(trifluoromethyl)anilino]-N-(1,3-benzodioxol-5-yl)acetamide
CAS 428487-07-4C22H17F3N2O5S
N-(1,3-Benzodioxol-5-yl)-2-(2-ethyl-N-(4-methylphenyl)sulfonylanilino)acetamide chemical structure, C24H24N2O5S, CAS 333747-66-3
N-(1,3-Benzodioxol-5-yl)-2-(2-ethyl-N-(4-methylphenyl)sulfonylanilino)acetamide
CAS 333747-66-3C24H24N2O5S
2-[N-(Benzenesulfonyl)-4-chloro-2-methylanilino]-N-(1,3-benzodioxol-5-yl)acetamide chemical structure, C22H19ClN2O5S, CAS 412919-89-2
2-[N-(Benzenesulfonyl)-4-chloro-2-methylanilino]-N-(1,3-benzodioxol-5-yl)acetamide
CAS 412919-89-2C22H19ClN2O5S
N-(1,3-Benzodioxol-5-yl)-2-(N-(4-methylphenyl)sulfonylanilino)acetamide chemical structure, C22H20N2O5S, CAS 333747-91-4
N-(1,3-Benzodioxol-5-yl)-2-(N-(4-methylphenyl)sulfonylanilino)acetamide
CAS 333747-91-4C22H20N2O5S
N-(1,3-Benzodioxol-5-yl)-2-(N-(3,4-dimethoxyphenyl)sulfonyl-3,5-dimethylanilino)acetamide chemical structure, C25H26N2O7S, CAS 428501-90-0
N-(1,3-Benzodioxol-5-yl)-2-(N-(3,4-dimethoxyphenyl)sulfonyl-3,5-dimethylanilino)acetamide
CAS 428501-90-0C25H26N2O7S
N-(1,3-Benzodioxol-5-yl)-2-(4-chloro-N-(4-methoxyphenyl)sulfonylanilino)acetamide chemical structure, C22H19ClN2O6S, CAS 432538-17-5
N-(1,3-Benzodioxol-5-yl)-2-(4-chloro-N-(4-methoxyphenyl)sulfonylanilino)acetamide
CAS 432538-17-5C22H19ClN2O6S
N-(1,3-Benzodioxol-5-yl)-2-(2,3-dimethyl-N-(4-methylphenyl)sulfonylanilino)acetamide chemical structure, C24H24N2O5S, CAS 532432-97-6
N-(1,3-Benzodioxol-5-yl)-2-(2,3-dimethyl-N-(4-methylphenyl)sulfonylanilino)acetamide
CAS 532432-97-6C24H24N2O5S
2-[N-(Benzenesulfonyl)-3-nitroanilino]-N-(1,3-benzodioxol-5-yl)acetamide chemical structure, C21H17N3O7S, CAS 357323-34-3
2-[N-(Benzenesulfonyl)-3-nitroanilino]-N-(1,3-benzodioxol-5-yl)acetamide
CAS 357323-34-3C21H17N3O7S
N-(1,3-Benzodioxol-5-yl)-2-(N-(4-methoxyphenyl)sulfonyl-4-methylanilino)acetamide chemical structure, C23H22N2O6S, CAS 432002-63-6
N-(1,3-Benzodioxol-5-yl)-2-(N-(4-methoxyphenyl)sulfonyl-4-methylanilino)acetamide
CAS 432002-63-6C23H22N2O6S
N-(1,3-Benzodioxol-5-yl)-2-(N-(4-fluorophenyl)sulfonylanilino)acetamide chemical structure, C21H17FN2O5S, CAS 831212-75-0
N-(1,3-Benzodioxol-5-yl)-2-(N-(4-fluorophenyl)sulfonylanilino)acetamide
CAS 831212-75-0C21H17FN2O5S
N-(1,3-Benzodioxol-5-yl)-2-(3-chloro-4-methoxy-N-(4-methylphenyl)sulfonylanilino)acetamide chemical structure, C23H21ClN2O6S, CAS 6492-62-2
N-(1,3-Benzodioxol-5-yl)-2-(3-chloro-4-methoxy-N-(4-methylphenyl)sulfonylanilino)acetamide
CAS 6492-62-2C23H21ClN2O6S