CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 26 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
10
With full pages
4
Scaffold SMILES

O=C(Nc1ccccc1N1CCNCC1)c1ccc(-c2ccccc2)o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1N1CCNCC1)c1ccc(-c2ccccc2)o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-[2-(4-Methylpiperazin-1-yl)phenyl]-5-(3-nitrophenyl)furan-2-carboxamide chemical structure, C22H22N4O4, CAS 717894-95-6
N-[2-(4-Methylpiperazin-1-yl)phenyl]-5-(3-nitrophenyl)furan-2-carboxamide
CAS 717894-95-6C22H22N4O4
5-(4-Bromophenyl)-N-[2-(4-methylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C22H22BrN3O2, CAS 792946-11-3
5-(4-Bromophenyl)-N-[2-(4-methylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 792946-11-3C22H22BrN3O2
N-[2-(4-Acetylpiperazin-1-yl)phenyl]-5-(2,4-dichlorophenyl)furan-2-carboxamide chemical structure, C23H21Cl2N3O3, CAS 831249-29-7
N-[2-(4-Acetylpiperazin-1-yl)phenyl]-5-(2,4-dichlorophenyl)furan-2-carboxamide
CAS 831249-29-7C23H21Cl2N3O3
5-(4-Chlorophenyl)-N-[2-(4-propanoylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C24H24ClN3O3, CAS 693830-04-5
5-(4-Chlorophenyl)-N-[2-(4-propanoylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 693830-04-5C24H24ClN3O3
5-(4-Bromophenyl)-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]furan-2-carboxamide chemical structure, C25H26BrN3O3, CAS 847478-19-7
5-(4-Bromophenyl)-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]furan-2-carboxamide
CAS 847478-19-7C25H26BrN3O3
5-(4-Chlorophenyl)-N-[5-chloro-2-(4-propanoylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C24H23Cl2N3O3, CAS 831244-52-1
5-(4-Chlorophenyl)-N-[5-chloro-2-(4-propanoylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 831244-52-1C24H23Cl2N3O3
N-[2-(4-Acetylpiperazin-1-yl)phenyl]-5-(3-nitrophenyl)furan-2-carboxamide chemical structure, C23H22N4O5, CAS 792946-38-4
N-[2-(4-Acetylpiperazin-1-yl)phenyl]-5-(3-nitrophenyl)furan-2-carboxamide
CAS 792946-38-4C23H22N4O5
5-(4-Chlorophenyl)-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C22H22ClN3O4S, CAS 1010859-78-5
5-(4-Chlorophenyl)-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 1010859-78-5C22H22ClN3O4S
5-(4-Chlorophenyl)-N-[2-(4-isobutyryl-1-piperazinyl)phenyl]-2-furamide chemical structure, C25H26ClN3O3, CAS 724449-27-8
5-(4-Chlorophenyl)-N-[2-(4-isobutyryl-1-piperazinyl)phenyl]-2-furamide
CAS 724449-27-8C25H26ClN3O3
Methyl 3-[[5-(4-chlorophenyl)furan-2-carbonyl]amino]-4-(4-methylpiperazin-1-yl)benzoate chemical structure, C24H24ClN3O4, CAS 892201-13-7
Methyl 3-[[5-(4-chlorophenyl)furan-2-carbonyl]amino]-4-(4-methylpiperazin-1-yl)benzoate
CAS 892201-13-7C24H24ClN3O4