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Murcko scaffold

2-(Morpholin-4-ylmethyl)-4,5-diphenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione scaffold

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
6
With full pages
1
Scaffold SMILES

S=c1n(CN2CCOCC2)nc(-c2ccccc2)n1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Morpholin-4-ylmethyl)-4,5-diphenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione page
Murcko scaffold S=c1n(CN2CCOCC2)nc(-c2ccccc2)n1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

5-(4-Bromophenyl)-4-(4-ethoxyphenyl)-2-(4-morpholinylmethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione chemical structure, C21H23BrN4O2S, CAS 397291-09-7
5-(4-Bromophenyl)-4-(4-ethoxyphenyl)-2-(4-morpholinylmethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione
CAS 397291-09-7C21H23BrN4O2S
2-(Morpholin-4-ylmethyl)-4,5-diphenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione chemical structure, C19H20N4OS, CAS 56807-58-0
2-(Morpholin-4-ylmethyl)-4,5-diphenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione
CAS 56807-58-0C19H20N4OS
5-(3,4-Dimethoxyphenyl)-2-(morpholin-4-ylmethyl)-4-phenyl-1,2,4-triazole-3-thione chemical structure, C21H24N4O3S, CAS 311796-96-0
5-(3,4-Dimethoxyphenyl)-2-(morpholin-4-ylmethyl)-4-phenyl-1,2,4-triazole-3-thione
CAS 311796-96-0C21H24N4O3S
5-(2-Chlorophenyl)-2-(morpholin-4-ylmethyl)-4-phenyl-1,2,4-triazole-3-thione chemical structure, C19H19ClN4OS, CAS 311774-65-9
5-(2-Chlorophenyl)-2-(morpholin-4-ylmethyl)-4-phenyl-1,2,4-triazole-3-thione
CAS 311774-65-9C19H19ClN4OS
5-(4-Methoxyphenyl)-2-(morpholin-4-ylmethyl)-4-phenyl-1,2,4-triazole-3-thione chemical structure, C20H22N4O2S, CAS 5602-29-9
5-(4-Methoxyphenyl)-2-(morpholin-4-ylmethyl)-4-phenyl-1,2,4-triazole-3-thione
CAS 5602-29-9C20H22N4O2S
5-(4-Chlorophenyl)-2,4-dihydro-2-(4-morpholinylmethyl)-4-phenyl-3H-1,2,4-triazole-3-thione chemical structure, C19H19ClN4OS, CAS 189372-26-7
5-(4-Chlorophenyl)-2,4-dihydro-2-(4-morpholinylmethyl)-4-phenyl-3H-1,2,4-triazole-3-thione
CAS 189372-26-7C19H19ClN4OS