Murcko scaffold
8-Benzyl-8-azabicyclo[3.2.1]octane scaffold
48 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 15
- Chemicals
- 48
- With full pages
- 2
Scaffold SMILES
c1ccc(CN2C3CCCC2CC3)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 48 chemicals
![8-Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine chemical structure, C14H20N2, CAS 76272-36-1](/s/TZWXPIKAEAYGPF-AGUYFDCRSA-N.svg)
8-Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine
CAS 76272-36-1C14H20N2
![N-((1R,3s,5S)-8-Benzyl-8-azabicyclo[3.2.1]octan-3-yl)isobutyramide chemical structure, C18H26N2O, CAS 376348-67-3](/s/ABOGULQHPLDMLL-ALOPSCKCSA-N.svg)
N-((1R,3s,5S)-8-Benzyl-8-azabicyclo[3.2.1]octan-3-yl)isobutyramide
CAS 376348-67-3C18H26N2O
![N-(8-Benzyl-8-aza-bicyclo[3.2.1]octan-3-yl)isobutyramide chemical structure, C18H26N2O, CAS 1160844-31-4](/s/ABOGULQHPLDMLL-UHFFFAOYSA-N.svg)
N-(8-Benzyl-8-aza-bicyclo[3.2.1]octan-3-yl)isobutyramide
CAS 1160844-31-4C18H26N2O
8-Benzyl-8-azabicyclo(3.2.1)octan-3-amine
CAS 96901-92-7C14H20N2
![8-Benzyl-8-azabicyclo[3.2.1]octane chemical structure, C14H19N, CAS 19079-79-9](/s/MVSNFUWCTULLSI-UHFFFAOYSA-N.svg)
8-Benzyl-8-azabicyclo[3.2.1]octane
CAS 19079-79-9C14H19N
![8-Benzyl-8-azabicyclo[3.2.1]octan-3-ol chemical structure, C14H19NO, CAS 3804-68-0](/s/HCBGIBWAPOFRKI-UHFFFAOYSA-N.svg)
8-Benzyl-8-azabicyclo[3.2.1]octan-3-ol
CAS 3804-68-0C14H19NO
N-Benzylnortropine
CAS 18717-73-2C14H19NO
![tert-Butyl (8-benzyl-8-azabicyclo[3.2.1]octan-3-yl)carbamate chemical structure, C19H28N2O2, CAS 287114-24-3](/s/CMJXLUWENNOYSU-UHFFFAOYSA-N.svg)
tert-Butyl (8-benzyl-8-azabicyclo[3.2.1]octan-3-yl)carbamate
CAS 287114-24-3C19H28N2O2
![8-Benzyl-N-methyl-8-azabicyclo[3.2.1]octan-3-amine chemical structure, C15H22N2, CAS 1334149-59-5](/s/HLTSXIQQDWKWBM-UHFFFAOYSA-N.svg)
8-Benzyl-N-methyl-8-azabicyclo[3.2.1]octan-3-amine
CAS 1334149-59-5C15H22N2
![8-Benzyl-8-azabicyclo[3.2.1]octane-3-carboxylic acid chemical structure, C15H19NO2, CAS 1209251-15-9](/s/DUBXJYDLYSDKOX-UHFFFAOYSA-N.svg)
8-Benzyl-8-azabicyclo[3.2.1]octane-3-carboxylic acid
CAS 1209251-15-9C15H19NO2
![(8-Benzyl-8-azabicyclo[3.2.1]octan-3-yl)methanamine chemical structure, C15H22N2, CAS 223570-84-1](/s/AKNRJMCMMROJED-UHFFFAOYSA-N.svg)
(8-Benzyl-8-azabicyclo[3.2.1]octan-3-yl)methanamine
CAS 223570-84-1C15H22N2
![8-Benzyl-8-azabicyclo[3.2.1]octane-3-carbonitrile chemical structure, C15H18N2, CAS 185985-38-0](/s/LLRRVHBPMZWOQV-UHFFFAOYSA-N.svg)
8-Benzyl-8-azabicyclo[3.2.1]octane-3-carbonitrile
CAS 185985-38-0C15H18N2
![Methyl 8-benzyl-8-azabicyclo[3.2.1]octane-3-carboxylate chemical structure, C16H21NO2, CAS 179022-42-5](/s/BZZQILCSEHKVBQ-UHFFFAOYSA-N.svg)
Methyl 8-benzyl-8-azabicyclo[3.2.1]octane-3-carboxylate
CAS 179022-42-5C16H21NO2
![1,1-Dimethylethyl N-[[8-(phenylmethyl)-8-azabicyclo[3.2.1]oct-3-yl]methyl]carbamate chemical structure, C20H30N2O2, CAS 871727-13-8](/s/AAWVOEWJHMNAJC-UHFFFAOYSA-N.svg)
1,1-Dimethylethyl N-[[8-(phenylmethyl)-8-azabicyclo[3.2.1]oct-3-yl]methyl]carbamate
CAS 871727-13-8C20H30N2O2
![8-Benzyl-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-8-ium chloride chemical structure, C15H22ClNO, CAS 17812-44-1](/s/RJSBZWOWLKKJQJ-UHFFFAOYSA-M.svg)
8-Benzyl-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-8-ium chloride
CAS 17812-44-1C15H22ClNO
![8-(3-Chloro-5-fluorobenzyl)-3-((methylamino)methyl)-8-aza-bicyclo[3.2.1]octan-3-ol chemical structure, C16H22ClFN2O, CAS 1222541-20-9](/s/BKKAPFQCJDVXQI-UHFFFAOYSA-N.svg)
8-(3-Chloro-5-fluorobenzyl)-3-((methylamino)methyl)-8-aza-bicyclo[3.2.1]octan-3-ol
CAS 1222541-20-9C16H22ClFN2O
![{8-Benzyl-8-azabicyclo[3.2.1]octan-3-yl}methanol chemical structure, C15H21NO, CAS 1209122-81-5](/s/NNUVOEBIDCULPG-UHFFFAOYSA-N.svg)
{8-Benzyl-8-azabicyclo[3.2.1]octan-3-yl}methanol
CAS 1209122-81-5C15H21NO
![8-Benzyl-3-hydrazinyl-8-azabicyclo[3.2.1]octane chemical structure, C14H21N3, CAS 1209814-34-5](/s/AVKOTGVIMWVXLA-UHFFFAOYSA-N.svg)
8-Benzyl-3-hydrazinyl-8-azabicyclo[3.2.1]octane
CAS 1209814-34-5C14H21N3
![8-Benzyl-3-(trifluoromethyl)-8-azabicyclo[3.2.1]octan-3-ol chemical structure, C15H18F3NO, CAS 1251925-32-2](/s/BVMLMRWOGJTNKB-UHFFFAOYSA-N.svg)
8-Benzyl-3-(trifluoromethyl)-8-azabicyclo[3.2.1]octan-3-ol
CAS 1251925-32-2C15H18F3NO
![8-Benzyl-8-azabicyclo[3.2.1]octane-3-carboxylic acid hydrochloride chemical structure, C15H20ClNO2, CAS 1311316-62-7](/s/YGYQDLPUNUNLFC-UHFFFAOYSA-N.svg)
8-Benzyl-8-azabicyclo[3.2.1]octane-3-carboxylic acid hydrochloride
CAS 1311316-62-7C15H20ClNO2
![8-{[4-(Methylsulfanyl)phenyl]methyl}-8-azabicyclo[3.2.1]octan-3-ol chemical structure, C15H21NOS, CAS 1272110-09-4](/s/WENMCAHVZIVJSZ-UHFFFAOYSA-N.svg)
8-{[4-(Methylsulfanyl)phenyl]methyl}-8-azabicyclo[3.2.1]octan-3-ol
CAS 1272110-09-4C15H21NOS
![3-(1,1-Dimethylethyl)-8-(phenylmethyl)-8-azabicyclo[3.2.1]octan-3-ol chemical structure, C18H27NO, CAS 1058166-29-2](/s/BCTVUWWAOHNKJS-UHFFFAOYSA-N.svg)
3-(1,1-Dimethylethyl)-8-(phenylmethyl)-8-azabicyclo[3.2.1]octan-3-ol
CAS 1058166-29-2C18H27NO
![8-Benzyl-3-methyl-8-azabicyclo[3.2.1]octan-3-ol chemical structure, C15H21NO, CAS 1058166-28-1](/s/JJEDXOPZTSQJJJ-UHFFFAOYSA-N.svg)
8-Benzyl-3-methyl-8-azabicyclo[3.2.1]octan-3-ol
CAS 1058166-28-1C15H21NO
![8-[(4-Bromophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-ol chemical structure, C14H18BrNO, CAS 1200131-62-9](/s/JFFJLNFTSQSKKB-UHFFFAOYSA-N.svg)
8-[(4-Bromophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-ol
CAS 1200131-62-9C14H18BrNO
- 8-{[4-(Trifluoromethyl)phenyl]methyl}-8-azabicyclo[3.2.1]octan-3-ol1408884-42-3C15H18F3NO
- 8-[(2-Chlorophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-ol1267495-82-8C14H18ClNO
- 8-[(3-Fluorophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-ol1410582-76-1C14H18FNO
- 8-[(4-Fluorophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-ol652148-00-0C14H18FNO
- 8-{[4-(Trifluoromethoxy)phenyl]methyl}-8-azabicyclo[3.2.1]octan-3-ol1485508-82-4C15H18F3NO2
- 8-[(2,5-Dimethylphenyl)methyl]-8-azabicyclo[3.2.1]octan-3-ol1487098-88-3C16H23NO
- 3-Amino-8-benzyl-8-azabicyclo[3.2.1]octane-3-carbonitrile142838-94-6C15H19N3
- (3-Endo)-8-benzyl-8-azabicyclo[3.2.1]octan-3-amine tetrahydrochloride hydrate612483-03-1C14H24Cl2N2O
- (3-Exo)-8-[(3,4-dichlorophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-amine76272-42-9C14H18Cl2N2
- 8-Benzyl-2-hydroxy-8-azabicyclo[3.2.1]octane-6-carbonitrile1909336-94-2C15H18N2O
- 8-Benzyl-8-azabicyclo[3.2.1]octan-3-amine hydrochloride1415560-32-5C14H21ClN2
- 3-Bromo-8-[(4-fluorophenyl)methyl]-8-azabicyclo[3.2.1]octane1514360-27-0C14H17BrFN
- (8-Benzyl-8-azabicyclo[3.2.1]octan-3-yl)acetonitrile1252572-63-6C16H20N2
- Methyl 2-exo-(8-benzyl-6,6-difluoro-8-azabicyclo[3.2.1]octan-3-yl)acetate1630906-57-8C17H21F2NO2
- (3-Endo)-N-allyl-8-benzyl-8-azabicyclo[3.2.1]octan-3-amine2197052-62-1C17H24N2
- N-Allyl-8-benzyl-8-azabicyclo[3.2.1]octan-3-amine1882352-79-5C17H24N2
- Benzyltropine hclC15H23ClNO+
- Wdx8749qpd1361964-33-1C20H30N4O
- 8-[(2-Chloro-3-methoxyphenyl)methyl]-8-azabicyclo[3.2.1]octan-3-ol2320381-54-0C15H20ClNO2
- (2-{3-[(8-Benzyl-8-azabicyclo[3.2.1]octan-3-yl)imino]-2-methylpropyl}hydrazinyl)acetic acid1185384-11-5C20H30N4O2
- N'-[3-(8-Benzyl-8-azabicyclo[3.2.1]octan-3-yl)-2-methylpropyl]acetohydrazide1184819-27-9C20H31N3O
- 2-[(8-Benzyl-8-azabicyclo[3.2.1]octan-3-yl)amino]-N'-(2-methylpropylidene)acetohydrazide1181208-30-9C20H30N4O
- 3-(8-Benzyl-8-azabicyclo[3.2.1]octan-2-yl)-2-methylpropanamide1184934-44-8C18H26N2O
- ((1S,2R,5S)-8-((R)-1-Phenylethyl)-8-azabicyclo[3.2.1]octan-2-yl)methanol2624127-18-8C16H23NO
Related scaffolds
Same ring framework with different atoms or bond orders
