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Murcko scaffold

Ring system with 2 rings and 7 atoms

11 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
7
Chemicals
11
With full pages
3
Scaffold SMILES

O=C1NCC2OC12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NCC2OC12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

6-Oxa-3-azabicyclo(3.1.0)hexane-1-carboxylic acid, 5-ethyl-4-hydroxy-4-methyl-2-oxo-, methyl ester chemical structure, C9H13NO5, CAS 142438-63-9
6-Oxa-3-azabicyclo(3.1.0)hexane-1-carboxylic acid, 5-ethyl-4-hydroxy-4-methyl-2-oxo-, methyl ester
CAS 142438-63-9C9H13NO5
Fusarin C chemical structure, C23H29NO7, CAS 79748-81-5
Fusarin C
CAS 79748-81-5C23H29NO7
Fusarin PM(sub 1) chemical structure, C22H27NO7, CAS 114661-56-2
Fusarin PM(sub 1)
CAS 114661-56-2C22H27NO7
Epolactaene chemical structure, C21H27NO6, CAS 167782-17-4
Epolactaene
CAS 167782-17-4C21H27NO6
tert-Butyl (2E,3E,5E,9E)-2-ethylidene-11-[(1R,5R)-4-hydroxy-4-methyl-2-oxo-6-oxa-3-azabicyclo[3.1.0]hexan-1-yl]-4,10-dimethyl-11-oxoundeca-3,5,9-trienoate chemical structure, C24H33NO6, CAS 634589-47-2
tert-Butyl (2E,3E,5E,9E)-2-ethylidene-11-[(1R,5R)-4-hydroxy-4-methyl-2-oxo-6-oxa-3-azabicyclo[3.1.0]hexan-1-yl]-4,10-dimethyl-11-oxoundeca-3,5,9-trienoate
CAS 634589-47-2C24H33NO6
4,5-Dimethyl-3,4-epoxy-5-hydroxy-3-(methylcarbonyl)-gamma-butyrolactam chemical structure, C8H11NO5, CAS 142438-62-8
4,5-Dimethyl-3,4-epoxy-5-hydroxy-3-(methylcarbonyl)-gamma-butyrolactam
CAS 142438-62-8C8H11NO5
3,4-Epoxy-5-hydroxy-5-isopropyl-3-(methoxycarbonyl)-4-methyl-gamma-butyrolactam chemical structure, C10H15NO5, CAS 142457-04-3
3,4-Epoxy-5-hydroxy-5-isopropyl-3-(methoxycarbonyl)-4-methyl-gamma-butyrolactam
CAS 142457-04-3C10H15NO5
(5Z)-Fusarin C chemical structure, C23H29NO7, CAS 194152-45-9
(5Z)-Fusarin C
CAS 194152-45-9C23H29NO7
(1R,5R)-6-Oxa-3-azabicyclo[3.1.0]hexan-2-one chemical structure, C4H5NO2, CAS 220812-15-7
(1R,5R)-6-Oxa-3-azabicyclo[3.1.0]hexan-2-one
CAS 220812-15-7C4H5NO2
Fusarin X chemical structure, C23H29NO8, CAS 145569-98-8
Fusarin X
CAS 145569-98-8C23H29NO8
(7Z)-Fusarin C chemical structure, C23H29NO7, CAS 90987-21-6
(7Z)-Fusarin C
CAS 90987-21-6C23H29NO7