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Murcko scaffold

Ring system with 3 rings and 19 atoms

82 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
82
With full pages
18
Scaffold SMILES

O=C(C=Cc1cccs1)Nc1nc2ccccc2s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1cccs1)Nc1nc2ccccc2s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 82 chemicals

(E)-N-(6-Nitro-1,3-benzothiazol-2-yl)-3-thiophen-2-ylprop-2-enamide chemical structure, C14H9N3O3S2, CAS 476308-19-7
(E)-N-(6-Nitro-1,3-benzothiazol-2-yl)-3-thiophen-2-ylprop-2-enamide
CAS 476308-19-7C14H9N3O3S2
(E)-N-(1,3-Benzothiazol-2-yl)-3-thiophen-2-ylprop-2-enamide chemical structure, C14H10N2OS2, CAS 378775-48-5
(E)-N-(1,3-Benzothiazol-2-yl)-3-thiophen-2-ylprop-2-enamide
CAS 378775-48-5C14H10N2OS2
(E)-N-(6-Chlorobenzo[d]thiazol-2-yl)-3-(thiophen-2-yl)acrylamide chemical structure, C14H9ClN2OS2, CAS 392323-02-3
(E)-N-(6-Chlorobenzo[d]thiazol-2-yl)-3-(thiophen-2-yl)acrylamide
CAS 392323-02-3C14H9ClN2OS2
(E)-N-(6-Methoxybenzo[d]thiazol-2-yl)-3-(thiophen-2-yl)acrylamide chemical structure, C15H12N2O2S2, CAS 392323-01-2
(E)-N-(6-Methoxybenzo[d]thiazol-2-yl)-3-(thiophen-2-yl)acrylamide
CAS 392323-01-2C15H12N2O2S2
(2E)-N-(6-Bromo-1,3-benzothiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide chemical structure, C14H9BrN2OS2, CAS 476307-91-2
(2E)-N-(6-Bromo-1,3-benzothiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide
CAS 476307-91-2C14H9BrN2OS2
2-Cyano-N-(6-methoxy-1,3-benzothiazol-2-yl)-3-(2-thienyl)acrylamide chemical structure, C16H11N3O2S2, CAS 354562-27-9
2-Cyano-N-(6-methoxy-1,3-benzothiazol-2-yl)-3-(2-thienyl)acrylamide
CAS 354562-27-9C16H11N3O2S2
(2E,NE)-N-(6-bromo-3-ethylbenzo[d]thiazol-2(3H)-ylidene)-3-(5-nitrothiophen-2-yl)acrylamide chemical structure, C16H12BrN3O3S2, CAS 865544-52-1
(2E,NE)-N-(6-bromo-3-ethylbenzo[d]thiazol-2(3H)-ylidene)-3-(5-nitrothiophen-2-yl)acrylamide
CAS 865544-52-1C16H12BrN3O3S2
(E)-N-(4,6-Difluorobenzo[d]thiazol-2-yl)-3-(thiophen-2-yl)acrylamide chemical structure, C14H8F2N2OS2, CAS 862807-14-5
(E)-N-(4,6-Difluorobenzo[d]thiazol-2-yl)-3-(thiophen-2-yl)acrylamide
CAS 862807-14-5C14H8F2N2OS2
(2E,NZ)-N-(3-ethyl-4-fluorobenzo[d]thiazol-2(3H)-ylidene)-3-(thiophen-2-yl)acrylamide chemical structure, C16H13FN2OS2, CAS 851080-03-0
(2E,NZ)-N-(3-ethyl-4-fluorobenzo[d]thiazol-2(3H)-ylidene)-3-(thiophen-2-yl)acrylamide
CAS 851080-03-0C16H13FN2OS2
(E)-N-(4-Fluorobenzo[d]thiazol-2-yl)-3-(thiophen-2-yl)acrylamide chemical structure, C14H9FN2OS2, CAS 862807-23-6
(E)-N-(4-Fluorobenzo[d]thiazol-2-yl)-3-(thiophen-2-yl)acrylamide
CAS 862807-23-6C14H9FN2OS2
(E)-N-(4-Methoxy-7-methylbenzo[d]thiazol-2-yl)-3-(thiophen-2-yl)acrylamide chemical structure, C16H14N2O2S2, CAS 862807-59-8
(E)-N-(4-Methoxy-7-methylbenzo[d]thiazol-2-yl)-3-(thiophen-2-yl)acrylamide
CAS 862807-59-8C16H14N2O2S2
(E)-N-(4,7-Dimethoxybenzo[d]thiazol-2-yl)-3-(thiophen-2-yl)acrylamide chemical structure, C16H14N2O3S2, CAS 862807-71-4
(E)-N-(4,7-Dimethoxybenzo[d]thiazol-2-yl)-3-(thiophen-2-yl)acrylamide
CAS 862807-71-4C16H14N2O3S2
N-(4-Chloro-3-ethyl-1,3-benzothiazol-2(3H)-ylidene)-3-(5-nitrothiophen-2-yl)prop-2-enamide chemical structure, C16H12ClN3O3S2, CAS 6285-25-2
N-(4-Chloro-3-ethyl-1,3-benzothiazol-2(3H)-ylidene)-3-(5-nitrothiophen-2-yl)prop-2-enamide
CAS 6285-25-2C16H12ClN3O3S2
(E)-Methyl 2-(3-(thiophen-2-yl)acrylamido)benzo[d]thiazole-6-carboxylate chemical structure, C16H12N2O3S2, CAS 864860-53-7
(E)-Methyl 2-(3-(thiophen-2-yl)acrylamido)benzo[d]thiazole-6-carboxylate
CAS 864860-53-7C16H12N2O3S2
(E)-N-(4-Methoxybenzo[d]thiazol-2-yl)-3-(5-nitrothiophen-2-yl)acrylamide chemical structure, C15H11N3O4S2, CAS 476319-99-0
(E)-N-(4-Methoxybenzo[d]thiazol-2-yl)-3-(5-nitrothiophen-2-yl)acrylamide
CAS 476319-99-0C15H11N3O4S2
(E)-N-(5,7-Dimethylbenzo[d]thiazol-2-yl)-3-(thiophen-2-yl)acrylamide chemical structure, C16H14N2OS2, CAS 896676-75-8
(E)-N-(5,7-Dimethylbenzo[d]thiazol-2-yl)-3-(thiophen-2-yl)acrylamide
CAS 896676-75-8C16H14N2OS2
(E)-N-(6-Nitrobenzo[d]thiazol-2-yl)-3-(5-nitrothiophen-2-yl)acrylamide chemical structure, C14H8N4O5S2, CAS 477547-85-6
(E)-N-(6-Nitrobenzo[d]thiazol-2-yl)-3-(5-nitrothiophen-2-yl)acrylamide
CAS 477547-85-6C14H8N4O5S2
(2E,NE)-N-(3,6-dimethylbenzo[d]thiazol-2(3H)-ylidene)-3-(thiophen-2-yl)acrylamide chemical structure, C16H14N2OS2, CAS 477294-94-3
(2E,NE)-N-(3,6-dimethylbenzo[d]thiazol-2(3H)-ylidene)-3-(thiophen-2-yl)acrylamide
CAS 477294-94-3C16H14N2OS2
(2E,NZ)-N-(6-chloro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(thiophen-2-yl)acrylamide chemical structure, C15H11ClN2OS2, CAS 476317-84-7
(2E,NZ)-N-(6-chloro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(thiophen-2-yl)acrylamide
CAS 476317-84-7C15H11ClN2OS2
(2E,NZ)-N-(6-chloro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(5-nitrothiophen-2-yl)acrylamide chemical structure, C15H10ClN3O3S2, CAS 476317-85-8
(2E,NZ)-N-(6-chloro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(5-nitrothiophen-2-yl)acrylamide
CAS 476317-85-8C15H10ClN3O3S2
(2E,NZ)-N-(3,6-dimethylbenzo[d]thiazol-2(3H)-ylidene)-3-(5-nitrothiophen-2-yl)acrylamide chemical structure, C16H13N3O3S2, CAS 477547-73-2
(2E,NZ)-N-(3,6-dimethylbenzo[d]thiazol-2(3H)-ylidene)-3-(5-nitrothiophen-2-yl)acrylamide
CAS 477547-73-2C16H13N3O3S2
(2E,NZ)-N-(3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(5-nitrothiophen-2-yl)acrylamide chemical structure, C15H11N3O3S2, CAS 477547-78-7
(2E,NZ)-N-(3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(5-nitrothiophen-2-yl)acrylamide
CAS 477547-78-7C15H11N3O3S2
(E)-N-[6-Acetamido-3-(2-methoxyethyl)-1,3-benzothiazol-2-ylidene]-3-thiophen-2-ylprop-2-enamide chemical structure, C19H19N3O3S2, CAS 1164518-03-9
(E)-N-[6-Acetamido-3-(2-methoxyethyl)-1,3-benzothiazol-2-ylidene]-3-thiophen-2-ylprop-2-enamide
CAS 1164518-03-9C19H19N3O3S2
(2E,NZ)-N-(6-chloro-3-(2-ethoxyethyl)benzo[d]thiazol-2(3H)-ylidene)-3-(thiophen-2-yl)acrylamide chemical structure, C18H17ClN2O2S2, CAS 865162-56-7
(2E,NZ)-N-(6-chloro-3-(2-ethoxyethyl)benzo[d]thiazol-2(3H)-ylidene)-3-(thiophen-2-yl)acrylamide
CAS 865162-56-7C18H17ClN2O2S2